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Page 1
Both Nitro Groups Are Essential for High Antitubercular Activity of 3,5-Dinitrobenzylsulfanyl Tetrazoles and 1,3,4-Oxadiazoles through the Deazaflavin-Dependent Nitroreductase Activation Pathway.
Karabanovich G, Fabiánová V, Vocat A, Dušek J, Valášková L, Stolaříková J, Kitson RRA, Pávek P, Vávrová K, Djaout K, Mikušová K, Baulard AR, Cole ST, Korduláková J, Roh J. Karabanovich G, et al. Among authors: dusek j. J Med Chem. 2024 Jan 11;67(1):81-109. doi: 10.1021/acs.jmedchem.3c00925. Epub 2023 Dec 29. J Med Chem. 2024. PMID: 38157261 Free PMC article.
Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase.
Karabanovich G, Dušek J, Savková K, Pavliš O, Pávková I, Korábečný J, Kučera T, Kočová Vlčková H, Huszár S, Konyariková Z, Konečná K, Jand'ourek O, Stolaříková J, Korduláková J, Vávrová K, Pávek P, Klimešová V, Hrabálek A, Mikušová K, Roh J. Karabanovich G, et al. Among authors: dusek j. J Med Chem. 2019 Sep 12;62(17):8115-8139. doi: 10.1021/acs.jmedchem.9b00912. Epub 2019 Aug 22. J Med Chem. 2019. PMID: 31393122
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure.
Mejdrová I, Dušek J, Škach K, Stefela A, Skoda J, Chalupský K, Dohnalová K, Pavkova I, Kronenberger T, Rashidian A, Smutná L, Duchoslav V, Smutny T, Pávek P, Nencka R. Mejdrová I, et al. Among authors: dusek j. J Med Chem. 2023 Feb 23;66(4):2422-2456. doi: 10.1021/acs.jmedchem.2c01140. Epub 2023 Feb 9. J Med Chem. 2023. PMID: 36756805 Free PMC article.
Comparison of HepaRG and HepG2 cell lines to model mitochondrial respiratory adaptations in non‑alcoholic fatty liver disease.
Maseko TE, Elkalaf M, Peterová E, Lotková H, Staňková P, Melek J, Dušek J, Žádníková P, Čížková D, Bezrouk A, Pávek P, Červinková Z, Kučera O. Maseko TE, et al. Among authors: dusek j. Int J Mol Med. 2024 Feb;53(2):18. doi: 10.3892/ijmm.2023.5342. Epub 2024 Jan 8. Int J Mol Med. 2024. PMID: 38186319 Free PMC article.
Filling the Blank Space: Branched 4-Nonylphenol Isomers Are Responsible for Robust Constitutive Androstane Receptor (CAR) Activation by Nonylphenol.
Rashidian A, Dušek J, Drastik M, Smutná L, Fritsche K, Braeuning A, Pijnenburg D, van Beuningen R, Honkakoski P, Poso A, Kronenberger T, Pavek P. Rashidian A, et al. Among authors: dusek j. Environ Sci Technol. 2024 Apr 23;58(16):6913-6923. doi: 10.1021/acs.est.3c10096. Epub 2024 Apr 9. Environ Sci Technol. 2024. PMID: 38593436
540 results