Toba S - Search Results

1

Combination therapy with oral antiviral and anti-inflammatory drugs improves the efficacy of delayed treatment in a COVID-19 hamster model.

Sasaki M, Sugi T, Iida S, Hirata Y, Kusakabe S, Konishi K, Itakura Y, Tabata K, Kishimoto M, Kobayashi H, Ariizumi T, Intaruck K, Nobori H, Toba S, Sato A, Matsuno K, Yamagishi J, Suzuki T, Hall WW, Orba Y, Sawa H. Sasaki M, et al. Among authors: toba s. EBioMedicine. 2024 Jan;99:104950. doi: 10.1016/j.ebiom.2023.104950. Epub 2023 Dec 30. EBioMedicine. 2024. PMID: 38159532 Free PMC article.

2

Identification of Compound-B, a novel anti-dengue virus agent targeting the non-structural protein 4A.

Nobori H, Toba S, Yoshida R, Hall WW, Orba Y, Sawa H, Sato A. Nobori H, et al. Among authors: toba s. Antiviral Res. 2018 Jul;155:60-66. doi: 10.1016/j.antiviral.2018.05.003. Epub 2018 May 11. Antiviral Res. 2018. PMID: 29758236

3

Inhibition of avian-origin influenza A(H7N9) virus by the novel cap-dependent endonuclease inhibitor baloxavir marboxil.

Taniguchi K, Ando Y, Nobori H, Toba S, Noshi T, Kobayashi M, Kawai M, Yoshida R, Sato A, Shishido T, Naito A, Matsuno K, Okamatsu M, Sakoda Y, Kida H. Taniguchi K, et al. Among authors: toba s. Sci Rep. 2019 Mar 5;9(1):3466. doi: 10.1038/s41598-019-39683-4. Sci Rep. 2019. PMID: 30837531 Free PMC article.

4

Identification of quinolone derivatives as effective anti-Dengue virus agents.

Nobori H, Uemura K, Toba S, Sanaki T, Shishido T, Hall WW, Orba Y, Sawa H, Sato A. Nobori H, et al. Among authors: toba s. Antiviral Res. 2020 Dec;184:104969. doi: 10.1016/j.antiviral.2020.104969. Epub 2020 Nov 4. Antiviral Res. 2020. PMID: 33160000

5

SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells.

Sasaki M, Uemura K, Sato A, Toba S, Sanaki T, Maenaka K, Hall WW, Orba Y, Sawa H. Sasaki M, et al. Among authors: toba s. PLoS Pathog. 2021 Jan 21;17(1):e1009233. doi: 10.1371/journal.ppat.1009233. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33476327 Free PMC article.

6

MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2.

Uemura K, Sasaki M, Sanaki T, Toba S, Takahashi Y, Orba Y, Hall WW, Maenaka K, Sawa H, Sato A. Uemura K, et al. Among authors: toba s. Sci Rep. 2021 Mar 8;11(1):5376. doi: 10.1038/s41598-021-84882-7. Sci Rep. 2021. PMID: 33686154 Free PMC article.

7

SARS-CoV-2 Bearing a Mutation at the S1/S2 Cleavage Site Exhibits Attenuated Virulence and Confers Protective Immunity.

Sasaki M, Toba S, Itakura Y, Chambaro HM, Kishimoto M, Tabata K, Intaruck K, Uemura K, Sanaki T, Sato A, Hall WW, Orba Y, Sawa H. Sasaki M, et al. Among authors: toba s. mBio. 2021 Aug 31;12(4):e0141521. doi: 10.1128/mBio.01415-21. Epub 2021 Aug 24. mBio. 2021. PMID: 34425707 Free PMC article.

8

Air-liquid interphase culture confers SARS-CoV-2 susceptibility to A549 alveolar epithelial cells.

Sasaki M, Kishimoto M, Itakura Y, Tabata K, Intaruck K, Uemura K, Toba S, Sanaki T, Sato A, Hall WW, Orba Y, Sawa H. Sasaki M, et al. Among authors: toba s. Biochem Biophys Res Commun. 2021 Nov 5;577:146-151. doi: 10.1016/j.bbrc.2021.09.015. Epub 2021 Sep 10. Biochem Biophys Res Commun. 2021. PMID: 34517212 Free PMC article.

9

5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2.

Uemura K, Nobori H, Sato A, Sanaki T, Toba S, Sasaki M, Murai A, Saito-Tarashima N, Minakawa N, Orba Y, Kariwa H, Hall WW, Sawa H, Matsuda A, Maenaka K. Uemura K, et al. Among authors: toba s. iScience. 2021 Oct 22;24(10):103120. doi: 10.1016/j.isci.2021.103120. Epub 2021 Sep 11. iScience. 2021. PMID: 34541466 Free PMC article.

10

Characterization of the In Vitro and In Vivo Efficacy of Baloxavir Marboxil against H5 Highly Pathogenic Avian Influenza Virus Infection.

Taniguchi K, Ando Y, Kobayashi M, Toba S, Nobori H, Sanaki T, Noshi T, Kawai M, Yoshida R, Sato A, Shishido T, Naito A, Matsuno K, Okamatsu M, Sakoda Y, Kida H. Taniguchi K, et al. Among authors: toba s. Viruses. 2022 Jan 8;14(1):111. doi: 10.3390/v14010111. Viruses. 2022. PMID: 35062315 Free PMC article.

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