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A fluorescent splice-switching mouse model enables high-throughput, sensitive quantification of antisense oligonucleotide delivery and activity.
Byrnes AE, Roudnicky F, Gogineni A, Soung AL, Xiong M, Hayne M, Heaster-Ford T, Shatz-Binder W, Dominguez SL, Imperio J, Gierke S, Roberts J, Guo J, Ghosh S, Yu C, Roose-Girma M, Elstrott J, Easton A, Hoogenraad CC. Byrnes AE, et al. Among authors: heaster ford t. Cell Rep Methods. 2024 Jan 22;4(1):100673. doi: 10.1016/j.crmeth.2023.100673. Epub 2024 Jan 2. Cell Rep Methods. 2024. PMID: 38171361 Free PMC article.