Synthesis, H2S releasing properties, antiviral and antioxidant activities and acute cardiac effects of nucleoside 5'-dithioacetates.
Bege M, Lovas M, Priksz D, Bernát B, Bereczki I, Kattoub RG, Kajtár R, Eskeif S, Novák L, Hodek J, Weber J, Herczegh P, Lekli I, Borbás A.
Bege M, et al.
Sci Rep. 2025 Jan 22;15(1):2876. doi: 10.1038/s41598-025-85351-1.
Sci Rep. 2025.
PMID: 39843902
The antioxidant activity of 5'-thionucleosides is significantly higher than that of trolox, but lower than that of ascorbic acid, while intact dithioacetates have no remarkable antioxidant effect. In human Calu cells, the guanosine derivative showed a moderate anti- …
The antioxidant activity of 5'-thionucleosides is significantly higher than that of trolox, but lower than that of ascorbic acid …