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Page 1
Discovery of Potent, Orally Bioavailable, Tricyclic NLRP3 Inhibitors.
Velcicky J, Janser P, Gommermann N, Brenneisen S, Ilic S, Vangrevelinghe E, Stiefl N, Boettcher A, Arnold C, Malinverni C, Dawson J, Murgasova R, Desrayaud S, Beltz K, Hinniger A, Dekker C, Farady CJ, Mackay A. Velcicky J, et al. Among authors: dekker c. J Med Chem. 2024 Jan 25;67(2):1544-1562. doi: 10.1021/acs.jmedchem.3c02098. Epub 2024 Jan 4. J Med Chem. 2024. PMID: 38175811
Discovery of NP3-253, a Potent Brain Penetrant Inhibitor of the NLRP3 Inflammasome.
Mackay A, Velcicky J, Gommermann N, Mattes H, Janser P, Wright M, Dubois C, Brenneisen S, Ilic S, Vangrevelinghe E, Stiefl N, Boettcher A, Schoenboerner M, Vogelsanger M, Muller-Bentz S, Kamke M, Rubert J, Kauffmann M, Desrayaud S, Trunzer M, Srinivas H, Hinniger A, von Burg N, Beltz K, Dekker C, Farady CJ. Mackay A, et al. Among authors: dekker c. J Med Chem. 2024 Dec 12;67(23):20780-20798. doi: 10.1021/acs.jmedchem.4c02350. Epub 2024 Nov 22. J Med Chem. 2024. PMID: 39574318
A phospho-harmonic orchestra plays the NLRP3 score.
Bornancin F, Dekker C. Bornancin F, et al. Among authors: dekker c. Front Immunol. 2023 Nov 3;14:1281607. doi: 10.3389/fimmu.2023.1281607. eCollection 2023. Front Immunol. 2023. PMID: 38022631 Free PMC article. Review.
Synchronization of E. coli Bacteria Moving in Coupled Microwells.
Japaridze A, Struijk V, Swamy K, Rosłoń I, Shoshani O, Dekker C, Alijani F. Japaridze A, et al. Among authors: dekker c. Small. 2024 Nov 25:e2407832. doi: 10.1002/smll.202407832. Online ahead of print. Small. 2024. PMID: 39584392
DNA supercoiling enhances DNA condensation by ParB proteins.
Martin-Gonzalez A, Tišma M, Analikwu BT, Barth A, Janissen R, Antar H, Kemps G, Gruber S, Dekker C. Martin-Gonzalez A, et al. Among authors: dekker c. Nucleic Acids Res. 2024 Nov 27;52(21):13255-13268. doi: 10.1093/nar/gkae936. Nucleic Acids Res. 2024. PMID: 39441069 Free PMC article.
Addendum: Directing Min protein patterns with advective bulk flow.
Meindlhumer S, Brauns F, Finžgar JR, Kerssemakers J, Dekker C, Frey E. Meindlhumer S, et al. Among authors: dekker c. Nat Commun. 2024 Aug 2;15(1):6522. doi: 10.1038/s41467-024-50256-6. Nat Commun. 2024. PMID: 39095392 Free PMC article. No abstract available.
536 results