Bowles KM - Search Results

1

Acute myeloid leukemia-driven IL-3-dependent upregulation of BCL2 in non-malignant hematopoietic stem and progenitor cells increases venetoclax-induced cytopenias.

Fowler-Shorten DJ, Maynard RS, Hampton K, Altera A, Markham M, Ehikioya M, Wojtowicz EE, Bowles KM, Rushworth SA, Hellmich C. Fowler-Shorten DJ, et al. Among authors: bowles km. Haematologica. 2024 May 1;109(5):1576-1581. doi: 10.3324/haematol.2023.283944. Haematologica. 2024. PMID: 38186347 Free PMC article. No abstract available.

2

NF-kappaB-inhibited acute myeloid leukemia cells are rescued from apoptosis by heme oxygenase-1 induction.

Rushworth SA, Bowles KM, Raninga P, MacEwan DJ. Rushworth SA, et al. Among authors: bowles km. Cancer Res. 2010 Apr 1;70(7):2973-83. doi: 10.1158/0008-5472.CAN-09-3407. Epub 2010 Mar 23. Cancer Res. 2010. PMID: 20332229

3

High basal nuclear levels of Nrf2 in acute myeloid leukemia reduces sensitivity to proteasome inhibitors.

Rushworth SA, Bowles KM, MacEwan DJ. Rushworth SA, et al. Among authors: bowles km. Cancer Res. 2011 Mar 1;71(5):1999-2009. doi: 10.1158/0008-5472.CAN-10-3018. Epub 2011 Jan 6. Cancer Res. 2011. PMID: 21212410

4

FLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanism.

Rushworth SA, Zaitseva L, Langa S, Bowles KM, MacEwan DJ. Rushworth SA, et al. Among authors: bowles km. Oncotarget. 2010 Sep;1(5):359-366. doi: 10.18632/oncotarget.168. Oncotarget. 2010. PMID: 21307400 Free PMC article.

5

Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1.

Heasman SA, Zaitseva L, Bowles KM, Rushworth SA, Macewan DJ. Heasman SA, et al. Among authors: bowles km. Oncotarget. 2011 Sep;2(9):658-68. doi: 10.18632/oncotarget.321. Oncotarget. 2011. PMID: 21911919 Free PMC article.

6

Bortezomib induces heme oxygenase-1 expression in multiple myeloma.

Barrera LN, Rushworth SA, Bowles KM, MacEwan DJ. Barrera LN, et al. Among authors: bowles km. Cell Cycle. 2012 Jun 15;11(12):2248-52. doi: 10.4161/cc.20343. Epub 2012 Jun 15. Cell Cycle. 2012. PMID: 22617388 Free PMC article.

7

BTK inhibitor ibrutinib is cytotoxic to myeloma and potently enhances bortezomib and lenalidomide activities through NF-κB.

Rushworth SA, Bowles KM, Barrera LN, Murray MY, Zaitseva L, MacEwan DJ. Rushworth SA, et al. Among authors: bowles km. Cell Signal. 2013 Jan;25(1):106-12. doi: 10.1016/j.cellsig.2012.09.008. Epub 2012 Sep 11. Cell Signal. 2013. PMID: 22975686

8

The high Nrf2 expression in human acute myeloid leukemia is driven by NF-κB and underlies its chemo-resistance.

Rushworth SA, Zaitseva L, Murray MY, Shah NM, Bowles KM, MacEwan DJ. Rushworth SA, et al. Among authors: bowles km. Blood. 2012 Dec 20;120(26):5188-98. doi: 10.1182/blood-2012-04-422121. Epub 2012 Oct 17. Blood. 2012. PMID: 23077289 Free article.

9

Attenuation of dexamethasone-induced cell death in multiple myeloma is mediated by miR-125b expression.

Murray MY, Rushworth SA, Zaitseva L, Bowles KM, Macewan DJ. Murray MY, et al. Among authors: bowles km. Cell Cycle. 2013 Jul 1;12(13):2144-53. doi: 10.4161/cc.25251. Epub 2013 Jun 11. Cell Cycle. 2013. PMID: 23759586 Free PMC article.

10

Understanding the role of NRF2-regulated miRNAs in human malignancies.

Shah NM, Rushworth SA, Murray MY, Bowles KM, MacEwan DJ. Shah NM, et al. Among authors: bowles km. Oncotarget. 2013 Aug;4(8):1130-42. doi: 10.18632/oncotarget.1181. Oncotarget. 2013. PMID: 24029073 Free PMC article. Review.

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