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Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma.
Hamel AR, Yan W, Rouhana JM, Monovarfeshani A, Jiang X, Mehta PA, Advani J, Luo Y, Liang Q, Rajasundaram S, Shrivastava A, Duchinski K, Mantena S, Wang J, van Zyl T, Pasquale LR, Swaroop A, Gharahkhani P, Khawaja AP, MacGregor S; International Glaucoma Genetics Consortium (IGGC); Chen R, Vitart V, Sanes JR, Wiggs JL, Segrè AV. Hamel AR, et al. Among authors: chen r. Nat Commun. 2024 Jan 9;15(1):396. doi: 10.1038/s41467-023-44380-y. Nat Commun. 2024. PMID: 38195602 Free PMC article.
Transcript isoforms of Reep6 have distinct functions in the retina.
Liang Q, Wu N, Zaneveld S, Liu H, Fu S, Wang K, Bertrand R, Wang J, Li Y, Chen R. Liang Q, et al. Among authors: chen r. Hum Mol Genet. 2021 Oct 13;30(21):1907-1918. doi: 10.1093/hmg/ddab157. Hum Mol Genet. 2021. PMID: 34104971 Free PMC article.
Clinical presentation, treatment, and genetic and histopathological analysis of juvenile cataracts and secondary glaucoma in a rhesus macaque (Macaca mulatta).
Casanova MI, Chen R, Garzel LM, Olstad KJ, Kim S, Harris RA, Li Y, Raveendran M, Liang Q, Wang J, Yiu G, Stout JT, Roberts JA, Rogers J, Moshiri A, Thomasy SM. Casanova MI, et al. Among authors: chen r. J Med Primatol. 2022 Apr;51(2):119-123. doi: 10.1111/jmp.12560. Epub 2021 Dec 12. J Med Primatol. 2022. PMID: 34897697 Free PMC article.
A multi-omics atlas of the human retina at single-cell resolution.
Liang Q, Cheng X, Wang J, Owen L, Shakoor A, Lillvis JL, Zhang C, Farkas M, Kim IK, Li Y, DeAngelis M, Chen R. Liang Q, et al. Among authors: chen r. Cell Genom. 2023 Apr 11;3(6):100298. doi: 10.1016/j.xgen.2023.100298. eCollection 2023 Jun 14. Cell Genom. 2023. PMID: 37388908 Free PMC article.
Integrated multi-omics single cell atlas of the human retina.
Li J, Wang J, Ibarra IL, Cheng X, Luecken MD, Lu J, Monavarfeshani A, Yan W, Zheng Y, Zuo Z, Colborn SLZ, Cortez BS, Owen LA, Tran NM, Shekhar K, Sanes JR, Stout JT, Chen S, Li Y, DeAngelis MM, Theis FJ, Chen R. Li J, et al. Among authors: chen r, chen s. Res Sq [Preprint]. 2023 Nov 17:rs.3.rs-3471275. doi: 10.21203/rs.3.rs-3471275/v1. Res Sq. 2023. PMID: 38014002 Free PMC article. Preprint.
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