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Page 1
Multiple redox switches of the SARS-CoV-2 main protease in vitro provide opportunities for drug design.
Funk LM, Poschmann G, Rabe von Pappenheim F, Chari A, Stegmann KM, Dickmanns A, Wensien M, Eulig N, Paknia E, Heyne G, Penka E, Pearson AR, Berndt C, Fritz T, Bazzi S, Uranga J, Mata RA, Dobbelstein M, Hilgenfeld R, Curth U, Tittmann K. Funk LM, et al. Among authors: curth u. Nat Commun. 2024 Jan 9;15(1):411. doi: 10.1038/s41467-023-44621-0. Nat Commun. 2024. PMID: 38195625 Free PMC article.
A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Wensien M, von Pappenheim FR, Funk LM, Kloskowski P, Curth U, Diederichsen U, Uranga J, Ye J, Fang P, Pan KT, Urlaub H, Mata RA, Sautner V, Tittmann K. Wensien M, et al. Among authors: curth u. Nature. 2021 May;593(7859):460-464. doi: 10.1038/s41586-021-03513-3. Epub 2021 May 5. Nature. 2021. PMID: 33953398
Survivin does not influence the anti-apoptotic action of XIAP on caspase-9.
Zumbrägel FK, Machtens DA, Curth U, Lüder CGK, Reubold TF, Eschenburg S. Zumbrägel FK, et al. Among authors: curth u. Biochem Biophys Res Commun. 2017 Jan 22;482(4):530-535. doi: 10.1016/j.bbrc.2016.11.094. Epub 2016 Nov 16. Biochem Biophys Res Commun. 2017. PMID: 27865841
Crystal structure of the dynamin tetramer.
Reubold TF, Faelber K, Plattner N, Posor Y, Ketel K, Curth U, Schlegel J, Anand R, Manstein DJ, Noé F, Haucke V, Daumke O, Eschenburg S. Reubold TF, et al. Among authors: curth u. Nature. 2015 Sep 17;525(7569):404-8. doi: 10.1038/nature14880. Epub 2015 Aug 24. Nature. 2015. PMID: 26302298
48 results