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Page 1
Missense and Loss of Function Variants at GWAS Loci in Familial Alzheimer's Disease.
Gunasekaran TI, Reyes-Dumeyer D, Faber KM, Goate A, Boeve B, Cruchaga C, Pericak-Vance M, Haines JL, Rosenberg R, Tsuang D, Mejia DR, Medrano M, Lantigua RA, Sweet RA, Bennett DA, Wilson RS, Alba C, Dalgard C, Foroud T, Vardarajan BN, Mayeux R. Gunasekaran TI, et al. Among authors: goate a. medRxiv [Preprint]. 2024 Jul 9:2023.12.18.23300145. doi: 10.1101/2023.12.18.23300145. medRxiv. 2024. Update in: Alzheimers Dement. 2024 Nov;20(11):7580-7594. doi: 10.1002/alz.14221 PMID: 38196599 Free PMC article. Updated. Preprint.
Systematic proteomics in Autosomal dominant Alzheimer's disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways.
Shen Y, Ali M, Timsina J, Wang C, Do A, Western D, Liu M, Gorijala P, Budde J, Liu H, Gordon B, McDade E, Morris JC, Llibre-Guerra JJ, Bateman RJ, Joseph-Mathurin N, Perrin RJ, Maschi D, Wyss-Coray T, Pastor P, Goate A, Renton AE, Surace EI, Johnson ECB, Levey AI, Alvarez I, Levin J, Ringman JM, Allegri RF, Seyfried N, Day GS, Wu Q, Fernández MV; Dominantly Inherited Alzheimer Network; Ibanez L, Sung YJ, Cruchaga C. Shen Y, et al. Among authors: goate a. medRxiv [Preprint]. 2024 Jan 13:2024.01.12.24301242. doi: 10.1101/2024.01.12.24301242. medRxiv. 2024. PMID: 38260583 Free PMC article. Preprint.
Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease.
Preische O, Schultz SA, Apel A, Kuhle J, Kaeser SA, Barro C, Gräber S, Kuder-Buletta E, LaFougere C, Laske C, Vöglein J, Levin J, Masters CL, Martins R, Schofield PR, Rossor MN, Graff-Radford NR, Salloway S, Ghetti B, Ringman JM, Noble JM, Chhatwal J, Goate AM, Benzinger TLS, Morris JC, Bateman RJ, Wang G, Fagan AM, McDade EM, Gordon BA, Jucker M; Dominantly Inherited Alzheimer Network. Preische O, et al. Among authors: goate am. Nat Med. 2019 Feb;25(2):277-283. doi: 10.1038/s41591-018-0304-3. Epub 2019 Jan 21. Nat Med. 2019. PMID: 30664784 Free PMC article.
Spatial proteomic differences in chronic traumatic encephalopathy, Alzheimer's disease, and primary age-related tauopathy hippocampi.
Richardson TE, Orr ME, Orr TC, Rohde SK, Ehrenberg AJ, Thorn EL, Christie TD, Flores-Almazan V, Afzal R, De Sanctis C, Maldonado-Díaz C, Hiya S, Canbeldek L, Kulumani Mahadevan LS, Slocum C, Samanamud J, Clare K, Scibetta N, Yokoda RT, Koenigsberg D, Marx GA, Kauffman J, Goldstein A, Selmanovic E, Drummond E, Wisniewski T, White CL 3rd, Goate AM, Crary JF, Farrell K, Alosco ML, Mez J, McKee AC, Stein TD, Bieniek KF, Kautz TF, Daoud EV, Walker JM. Richardson TE, et al. Among authors: goate am. Alzheimers Dement. 2024 Dec 31. doi: 10.1002/alz.14487. Online ahead of print. Alzheimers Dement. 2024. PMID: 39737785
Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus.
Matera A, Compagnion AC, Pedicone C, Kotah JM, Ivanov A, Monsorno K, Labouèbe G, Leggio L, Pereira-Iglesias M, Beule D, Mansuy-Aubert V, Williams TL, Iraci N, Sierra A, Marro SG, Goate AM, Eggen BJL, Kerr WG, Paolicelli RC. Matera A, et al. Among authors: goate am. Immunity. 2025 Jan 14;58(1):197-217.e13. doi: 10.1016/j.immuni.2024.11.003. Epub 2024 Dec 9. Immunity. 2025. PMID: 39657671 Free article.
Author Correction: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.
Karlsson Linnér R, Mallard TT, Barr PB, Sanchez-Roige S, Madole JW, Driver MN, Poore HE, de Vlaming R, Grotzinger AD, Tielbeek JJ, Johnson EC, Liu M, Rosenthal SB, Ideker T, Zhou H, Kember RL, Pasman JA, Verweij KJH, Liu DJ, Vrieze S; COGA Collaborators; Kranzler HR, Gelernter J, Harris KM, Tucker-Drob EM, Waldman ID, Palmer AA, Harden KP, Koellinger PD, Dick DM. Karlsson Linnér R, et al. Nat Neurosci. 2025 Jan;28(1):213. doi: 10.1038/s41593-024-01853-7. Nat Neurosci. 2025. PMID: 39643700 No abstract available.
X-chromosome-wide association study for Alzheimer's disease.
Le Borgne J, Gomez L, Heikkinen S, Amin N, Ahmad S, Choi SH, Bis J, Grenier-Boley B, Rodriguez OG, Kleineidam L, Young J, Tripathi KP, Wang L, Varma A, Campos-Martin R, van der Lee S, Damotte V, de Rojas I, Palmal S; EADB, GR@ACE, DEGESCO, EADI, GERAD, DemGene, FinnGen, ADGC, CHARGE; Lipton R, Reiman E, McKee A, De Jager P, Bush W, Small S, Levey A, Saykin A, Foroud T, Albert M, Hyman B, Petersen R, Younkin S, Sano M, Wisniewski T, Vassar R, Schneider J, Henderson V, Roberson E, DeCarli C, LaFerla F, Brewer J, Swerdlow R, Van Eldik L, Hamilton-Nelson K, Paulson H, Naj A, Lopez O, Chui H, Crane P, Grabowski T, Kukull W, Asthana S, Craft S, Strittmatter S, Cruchaga C, Leverenz J, Goate A, Kamboh MI, George-Hyslop PS, Valladares O, Kuzma A, Cantwell L, Riemenschneider M, Morris J, Slifer S, Dalmasso C, Castillo A, Küçükali F, Peters O, Schneider A, Dichgans M, Rujescu D, Scherbaum N, Deckert J, Riedel-Heller S, Hausner L, Molina-Porcel L, Düzel E, Grimmer T, Wiltfang J, Heilmann-Heimbach S, Moebus S, Tegos T, Scarmeas N, Dols-Icardo O, Moreno F, Pérez-Tur J, Bullido MJ, Pastor P, Sánchez-Valle R, Álvarez V, Boada M, García-González P, Puerta R, Mir P, Real LM, Piñol-Ripoll G, … See abstract for full author list ➔ Le Borgne J, et al. Among authors: goate a. Mol Psychiatry. 2024 Dec 4. doi: 10.1038/s41380-024-02838-5. Online ahead of print. Mol Psychiatry. 2024. PMID: 39633006
Childhood trauma is associated with developmental trajectories of EEG coherence, alcohol-related outcomes, and PTSD symptoms.
Neale ZE, Bountress K, Sheerin C, Saenz de Viteri S, Cusack S, Chorlian D, Barr PB, Kaplan I, Pandey G, Osipenko KA, McCutcheon V, Kuo SI, Cooke ME, Brislin SJ, Salvatore JE, Kamarajan C; COGA Investigators; Porjesz B, Amstadter AB, Meyers JL. Neale ZE, et al. Psychol Med. 2024 Dec 2;54(15):1-14. doi: 10.1017/S0033291724002599. Online ahead of print. Psychol Med. 2024. PMID: 39620481 Free PMC article.
738 results