Courade JP - Search Results

1

Distinct tau and alpha-synuclein molecular signatures in Alzheimer's disease with and without Lewy bodies and Parkinson's disease with dementia.

van der Gaag BL, Deshayes NAC, Breve JJP, Bol JGJM, Jonker AJ, Hoozemans JJM, Courade JP, van de Berg WDJ. van der Gaag BL, et al. Among authors: courade jp. Acta Neuropathol. 2024 Jan 10;147(1):14. doi: 10.1007/s00401-023-02657-y. Acta Neuropathol. 2024. PMID: 38198008 Free PMC article.

2

Analysis of clinical failure of anti-tau and anti-synuclein antibodies in neurodegeneration using a quantitative systems pharmacology model.

Geerts H, Bergeler S, Walker M, van der Graaf PH, Courade JP. Geerts H, et al. Among authors: courade jp. Sci Rep. 2023 Sep 1;13(1):14342. doi: 10.1038/s41598-023-41382-0. Sci Rep. 2023. PMID: 37658103 Free PMC article.

3

Discovery of UCB9386: A Potent, Selective, and Brain-Penetrant Nuak1 Inhibitor Suitable for In Vivo Pharmacological Studies.

Poullennec KG, Jnoff E, Abendroth J, Bhuma N, Calmiano M, Calmus L, Cardenas A, Courade JP, Delatour C, Hall A, de Haro T, Delker SL, Demaude T, Gaikwad N, Ghavate D, Gholap AR, Kierkowicz M, Le Mestre R, Van Hijfte N, Verheijden S, Vernerova K, De Wever V, Waghmode N. Poullennec KG, et al. Among authors: courade jp. J Med Chem. 2024 Dec 12;67(23):20879-20910. doi: 10.1021/acs.jmedchem.4c01237. Epub 2024 Nov 26. J Med Chem. 2024. PMID: 39588908

4

A call for better understanding of target engagement in Tau antibody development.

Bespalov A, Courade JP, Khiroug L, Terstappen GC, Wang Y. Bespalov A, et al. Among authors: courade jp. Drug Discov Today. 2022 Nov;27(11):103338. doi: 10.1016/j.drudis.2022.103338. Epub 2022 Aug 13. Drug Discov Today. 2022. PMID: 35973661

5

From the prion-like propagation hypothesis to therapeutic strategies of anti-tau immunotherapy.

Colin M, Dujardin S, Schraen-Maschke S, Meno-Tetang G, Duyckaerts C, Courade JP, Buée L. Colin M, et al. Among authors: courade jp. Acta Neuropathol. 2020 Jan;139(1):3-25. doi: 10.1007/s00401-019-02087-9. Epub 2019 Nov 4. Acta Neuropathol. 2020. PMID: 31686182 Free PMC article. Review.

6

Prevention of tau seeding and propagation by immunotherapy with a central tau epitope antibody.

Albert M, Mairet-Coello G, Danis C, Lieger S, Caillierez R, Carrier S, Skrobala E, Landrieu I, Michel A, Schmitt M, Citron M, Downey P, Courade JP, Buée L, Colin M. Albert M, et al. Among authors: courade jp. Brain. 2019 Jun 1;142(6):1736-1750. doi: 10.1093/brain/awz100. Brain. 2019. PMID: 31038156 Free PMC article.

7

Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau.

Courade JP, Angers R, Mairet-Coello G, Pacico N, Tyson K, Lightwood D, Munro R, McMillan D, Griffin R, Baker T, Starkie D, Nan R, Westwood M, Mushikiwabo ML, Jung S, Odede G, Sweeney B, Popplewell A, Burgess G, Downey P, Citron M. Courade JP, et al. Acta Neuropathol. 2018 Nov;136(5):729-745. doi: 10.1007/s00401-018-1911-2. Epub 2018 Sep 20. Acta Neuropathol. 2018. PMID: 30238240 Free PMC article.

8

The tau positron-emission tomography tracer AV-1451 binds with similar affinities to tau fibrils and monoamine oxidases.

Vermeiren C, Motte P, Viot D, Mairet-Coello G, Courade JP, Citron M, Mercier J, Hannestad J, Gillard M. Vermeiren C, et al. Among authors: courade jp. Mov Disord. 2018 Feb;33(2):273-281. doi: 10.1002/mds.27271. Epub 2017 Dec 26. Mov Disord. 2018. PMID: 29278274

9

Alternative to LRRK2-IN-1 for Pharmacological Studies of Parkinson's Disease.

Koshibu K, van Asperen J, Gerets H, Garcia-Ladona J, Lorthioir O, Courade JP. Koshibu K, et al. Among authors: courade jp. Pharmacology. 2015;96(5-6):240-7. doi: 10.1159/000439136. Epub 2015 Sep 18. Pharmacology. 2015. PMID: 26382237

10

Alterations in Spinal Cord Metabolism during Treatment of Neuropathic Pain.

Johnson CH, Patti GJ, Courade JP, Shriver LP, Hoang LT, Manchester M, Siuzdak G. Johnson CH, et al. Among authors: courade jp. J Neuroimmune Pharmacol. 2015 Sep;10(3):396-401. doi: 10.1007/s11481-015-9624-y. Epub 2015 Aug 2. J Neuroimmune Pharmacol. 2015. PMID: 26232265 Free PMC article.

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