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Page 1
The FOXP3+ Pro-Inflammatory T Cell: A Potential Therapeutic Target in Crohn's Disease.
Kosinsky RL, Gonzalez MM, Saul D, Barros LL, Sagstetter MR, Fedyshyn Y, Nair A, Sun Z, Hamdan FH, Gibbons HR, Perez Pachon ME, Druliner BR, Johnsen SA, Faubion WA. Kosinsky RL, et al. Among authors: sagstetter mr. Gastroenterology. 2024 Apr;166(4):631-644.e17. doi: 10.1053/j.gastro.2024.01.007. Epub 2024 Jan 9. Gastroenterology. 2024. PMID: 38211712
The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD).
Sarmento OF, Svingen PA, Xiong Y, Sun Z, Bamidele AO, Mathison AJ, Smyrk TC, Nair AA, Gonzalez MM, Sagstetter MR, Baheti S, McGovern DP, Friton JJ, Papadakis KA, Gautam G, Xavier RJ, Urrutia RA, Faubion WA. Sarmento OF, et al. Among authors: sagstetter mr. J Biol Chem. 2017 Jan 13;292(2):706-722. doi: 10.1074/jbc.M116.749663. Epub 2016 Dec 1. J Biol Chem. 2017. PMID: 27909059 Free PMC article.
Disruption of FOXP3-EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal Inflammation.
Bamidele AO, Svingen PA, Sagstetter MR, Sarmento OF, Gonzalez M, Braga Neto MB, Kugathasan S, Lomberk G, Urrutia RA, Faubion WA Jr. Bamidele AO, et al. Among authors: sagstetter mr. Cell Mol Gastroenterol Hepatol. 2018 Sep 14;7(1):55-71. doi: 10.1016/j.jcmgh.2018.08.009. eCollection 2019. Cell Mol Gastroenterol Hepatol. 2018. PMID: 30510991 Free PMC article.
BMI1 maintains the Treg epigenomic landscape to prevent inflammatory bowel disease.
Gonzalez MM, Bamidele AO, Svingen PA, Sagstetter MR, Smyrk TC, Gaballa JM, Hamdan FH, Kosinsky RL, Gibbons HR, Sun Z, Ye Z, Nair A, Ramos GP, Braga Neto MB, Wixom AQ, Mathison AJ, Johnsen SA, Urrutia R, Faubion WA Jr. Gonzalez MM, et al. Among authors: sagstetter mr. J Clin Invest. 2021 Jun 15;131(12):e140755. doi: 10.1172/JCI140755. J Clin Invest. 2021. PMID: 34128475 Free PMC article.
G9a Modulates Lipid Metabolism in CD4 T Cells to Regulate Intestinal Inflammation.
Ramos GP, Bamidele AO, Klatt EE, Sagstetter MR, Kurdi AT, Hamdan FH, Kosinsky RL, Gaballa JM, Nair A, Sun Z, Dasari S, Lanza IR, Rozeveld CN, Schott MB, Urrutia G, Westphal MS, Clarkson BD, Howe CL, Marietta EV, Luckey DH, Murray JA, Gonzalez M, Braga Neto MB, Gibbons HR, Smyrk TC, Johnsen S, Lomberk G, Faubion WA. Ramos GP, et al. Among authors: sagstetter mr. Gastroenterology. 2023 Feb;164(2):256-271.e10. doi: 10.1053/j.gastro.2022.10.011. Epub 2022 Oct 20. Gastroenterology. 2023. PMID: 36272457 Free PMC article.
Interleukin 21 Drives a Hypermetabolic State and CD4+ T-Cell-Associated Pathogenicity in Chronic Intestinal Inflammation.
Bamidele AO, Mishra SK, Piovezani Ramos G, Hirsova P, Klatt EE, Abdelrahman LM, Sagstetter MR, Davidson HM, Fehrenbach PJ, Valenzuela-Pérez L, Kim Lee HS, Zhang S, Aguirre Lopez A, Kurdi AT, Westphal MS, Gonzalez MM, Gaballa JM, Kosinsky RL, Lee HE, Smyrk TC, Bantug G, Gades NM, Faubion WA Jr. Bamidele AO, et al. Among authors: sagstetter mr. Gastroenterology. 2024 May;166(5):826-841.e19. doi: 10.1053/j.gastro.2024.01.026. Epub 2024 Jan 23. Gastroenterology. 2024. PMID: 38266738
12 results