Wajant H - Search Results

1

Genetically engineered IgG1 and nanobody oligomers acquire strong intrinsic CD40 agonism.

Hesen N, Anany M, Freidel A, Baker M, Siegmund D, Zaitseva O, Wajant H, Lang I. Hesen N, et al. Among authors: wajant h. Bioengineered. 2024 Dec;15(1):2302246. doi: 10.1080/21655979.2024.2302246. Epub 2024 Jan 12. Bioengineered. 2024. PMID: 38214443 Free PMC article.

2

FcγRs and Their Relevance for the Activity of Anti-CD40 Antibodies.

Lang I, Zaitseva O, Wajant H. Lang I, et al. Among authors: wajant h. Int J Mol Sci. 2022 Oct 25;23(21):12869. doi: 10.3390/ijms232112869. Int J Mol Sci. 2022. PMID: 36361658 Free PMC article. Review.

3

Basic characterization of antibodies targeting receptors of the tumor necrosis factor receptor superfamily.

Zaitseva O, Anany M, Wajant H, Lang I. Zaitseva O, et al. Among authors: wajant h. Front Immunol. 2023 Mar 27;14:1115667. doi: 10.3389/fimmu.2023.1115667. eCollection 2023. Front Immunol. 2023. PMID: 37051245 Free PMC article.

4

Generic design principles for antibody-based tumour necrosis factor (TNF) receptor 2 (TNFR2) agonists with FcγR-independent agonism.

Anany MA, Haack S, Lang I, Dahlhoff J, Vargas JG, Steinfatt T, Päckert L, Weisenberger D, Zaitseva O, Medler J, Kucka K, Zhang T, Van Belle T, van Rompaey L, Beilhack A, Wajant H. Anany MA, et al. Among authors: wajant h. Theranostics. 2024 Jan 1;14(2):496-509. doi: 10.7150/thno.84404. eCollection 2024. Theranostics. 2024. PMID: 38169605 Free PMC article.

5

Signaling active CD95 receptor molecules trigger co-translocation of inactive CD95 molecules into lipid rafts.

Lang I, Fick A, Schäfer V, Giner T, Siegmund D, Wajant H. Lang I, et al. Among authors: wajant h. J Biol Chem. 2012 Jul 6;287(28):24026-42. doi: 10.1074/jbc.M111.328211. Epub 2012 May 29. J Biol Chem. 2012. PMID: 22645131 Free PMC article.

6

TWEAK inhibits TRAF2-mediated CD40 signaling by destabilization of CD40 signaling complexes.

Salzmann S, Lang I, Rosenthal A, Schäfer V, Weisenberger D, Carmona Arana JA, Trebing J, Siegmund D, Neumann M, Wajant H. Salzmann S, et al. Among authors: wajant h. J Immunol. 2013 Sep 1;191(5):2308-18. doi: 10.4049/jimmunol.1202899. Epub 2013 Aug 5. J Immunol. 2013. PMID: 23918987

7

Cell death-independent activities of the death receptors CD95, TRAILR1, and TRAILR2.

Siegmund D, Lang I, Wajant H. Siegmund D, et al. Among authors: wajant h. FEBS J. 2017 Apr;284(8):1131-1159. doi: 10.1111/febs.13968. Epub 2016 Dec 14. FEBS J. 2017. PMID: 27865080 Free article. Review.

8

TNFR1 and TNFR2 in the Control of the Life and Death Balance of Macrophages.

Wajant H, Siegmund D. Wajant H, et al. Front Cell Dev Biol. 2019 May 29;7:91. doi: 10.3389/fcell.2019.00091. eCollection 2019. Front Cell Dev Biol. 2019. PMID: 31192209 Free PMC article. Review.

9

Anti-Fn14 Antibody-Conjugated Nanoparticles Display Membrane TWEAK-Like Agonism.

Aido A, Zaitseva O, Wajant H, Buzgo M, Simaite A. Aido A, et al. Among authors: wajant h. Pharmaceutics. 2021 Jul 13;13(7):1072. doi: 10.3390/pharmaceutics13071072. Pharmaceutics. 2021. PMID: 34371763 Free PMC article.

10

TNF and TNF receptors as therapeutic targets for rheumatic diseases and beyond.

Siegmund D, Wajant H. Siegmund D, et al. Among authors: wajant h. Nat Rev Rheumatol. 2023 Sep;19(9):576-591. doi: 10.1038/s41584-023-01002-7. Epub 2023 Aug 4. Nat Rev Rheumatol. 2023. PMID: 37542139 Review.

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