Sortwell CE - Search Results

1

Neuroinflammatory gene expression profiles of reactive glia in the substantia nigra suggest a multidimensional immune response to alpha synuclein inclusions.

Stoll AC, Kemp CJ, Patterson JR, Howe JW, Steece-Collier K, Luk KC, Sortwell CE, Benskey MJ. Stoll AC, et al. Among authors: sortwell ce. Neurobiol Dis. 2024 Feb;191:106411. doi: 10.1016/j.nbd.2024.106411. Epub 2024 Jan 14. Neurobiol Dis. 2024. PMID: 38228253 Free PMC article.

2

Microglial depletion does not impact alpha-synuclein aggregation or nigrostriatal degeneration in the rat preformed fibril model.

Stoll AC, Kemp CJ, Patterson JR, Kubik M, Kuhn N, Benskey M, Duffy MF, Luk K, Sortwell CE. Stoll AC, et al. Among authors: sortwell ce. Res Sq [Preprint]. 2023 May 4:rs.3.rs-2890683. doi: 10.21203/rs.3.rs-2890683/v1. Res Sq. 2023. PMID: 37205534 Free PMC article. Preprint.

3

Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils.

Patterson JR, Kochmanski J, Stoll AC, Kubik M, Kemp CJ, Duffy MF, Thompson K, Howe JW, Cole-Strauss A, Kuhn NC, Miller KM, Nelson S, Onyekpe CU, Beck JS, Counts SE, Bernstein AI, Steece-Collier K, Luk KC, Sortwell CE. Patterson JR, et al. Among authors: sortwell ce. NPJ Parkinsons Dis. 2024 Jan 3;10(1):7. doi: 10.1038/s41531-023-00620-y. NPJ Parkinsons Dis. 2024. PMID: 38172128 Free PMC article.

4

Deficits in basal and evoked striatal dopamine release following alpha-synuclein preformed fibril injection: An in vivo microdialysis study.

Centner A, Del Priore I, Chambers N, Cohen SR, Terry ML, Coyle M, Glinski J, Stoll AC, Patterson JR, Kemp CJ, Miller KM, Kubik M, Kuhn N, Luk KC, Sortwell CE, Bishop C. Centner A, et al. Among authors: sortwell ce. Eur J Neurosci. 2024 Apr;59(7):1585-1603. doi: 10.1111/ejn.16275. Epub 2024 Feb 14. Eur J Neurosci. 2024. PMID: 38356120

5

Alpha-synuclein inclusion responsive microglia are resistant to CSF1R inhibition.

Stoll AC, Kemp CJ, Patterson JR, Kubik M, Kuhn N, Benskey M, Duffy MF, Luk KC, Sortwell CE. Stoll AC, et al. Among authors: sortwell ce. J Neuroinflammation. 2024 Apr 25;21(1):108. doi: 10.1186/s12974-024-03108-5. J Neuroinflammation. 2024. PMID: 38664840 Free PMC article.

6

AAV9-Mediated Intrastriatal Delivery of GNAO1 Reduces Hyperlocomotion in Gnao1 Heterozygous R209H Mutant Mice.

Roy AJ, Leipprandt JR, Patterson JR, Stoll AC, Kemp CJ, Oula ZD, Mola T, Batista AR, Sortwell CE, Sena-Esteves M, Neubig RR. Roy AJ, et al. Among authors: sortwell ce. J Pharmacol Exp Ther. 2024 Jul 18;390(2):250-259. doi: 10.1124/jpet.124.002117. J Pharmacol Exp Ther. 2024. PMID: 38866563

7

Advancing age and the rs6265 BDNF SNP are permissive to graft-induced dyskinesias in parkinsonian rats.

Mercado NM, Szarowicz C, Stancati JA, Sortwell CE, Boezwinkle SA, Collier TJ, Caulfield ME, Steece-Collier K. Mercado NM, et al. Among authors: sortwell ce. NPJ Parkinsons Dis. 2024 Aug 23;10(1):163. doi: 10.1038/s41531-024-00771-6. NPJ Parkinsons Dis. 2024. PMID: 39179609 Free PMC article.

8

Quinpirole inhibits levodopa-induced dyskinesias at structural and behavioral levels: Efficacy negated by co-administration of isradipine.

Collier TJ, Begg L, Stancati JA, Mercado NM, Sellnow RC, Sandoval IM, Sortwell CE, Steece-Collier K. Collier TJ, et al. Among authors: sortwell ce. Exp Neurol. 2023 Nov;369:114522. doi: 10.1016/j.expneurol.2023.114522. Epub 2023 Aug 26. Exp Neurol. 2023. PMID: 37640098 Free PMC article.

9

Developmental exposure to the Parkinson's disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected mice.

Boyd SL, Kuhn NC, Patterson JR, Stoll AC, Zimmerman SA, Kolanowski MR, Neubecker JJ, Luk KC, Ramsson ES, Sortwell CE, Bernstein AI. Boyd SL, et al. Among authors: sortwell ce. Toxicol Sci. 2023 Oct 30;196(1):99-111. doi: 10.1093/toxsci/kfad086. Toxicol Sci. 2023. PMID: 37607008 Free PMC article.

10

Downregulation of striatal Ca_V1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age.

Caulfield ME, Vander Werp MJ, Stancati JA, Collier TJ, Sortwell CE, Sandoval IM, Manfredsson FP, Steece-Collier K. Caulfield ME, et al. Among authors: sortwell ce. Neurobiol Dis. 2023 Jun 1;181:106111. doi: 10.1016/j.nbd.2023.106111. Epub 2023 Mar 29. Neurobiol Dis. 2023. PMID: 37001610 Free PMC article.

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