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Page 1
Atomistic mechanisms of the regulation of small-conductance Ca2+-activated K+ channel (SK2) by PIP2.
Woltz RL, Zheng Y, Choi W, Ngo K, Trinh P, Ren L, Thai PN, Harris BJ, Han Y, Rouen KC, Mateos DL, Jian Z, Chen-Izu Y, Dickson EJ, Yamoah EN, Yarov-Yarovoy V, Vorobyov I, Zhang XD, Chiamvimonvat N. Woltz RL, et al. Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2318900121. doi: 10.1073/pnas.2318900121. Epub 2024 Sep 17. Proc Natl Acad Sci U S A. 2024. PMID: 39288178 Free PMC article.
The Piezo channel is a mechano-sensitive complex component in the mammalian inner ear hair cell.
Lee JH, Perez-Flores MC, Park S, Kim HJ, Chen Y, Kang M, Kersigo J, Choi J, Thai PN, Woltz RL, Perez-Flores DC, Perkins G, Sihn CR, Trinh P, Zhang XD, Sirish P, Dong Y, Feng WW, Pessah IN, Dixon RE, Sokolowski B, Fritzsch B, Chiamvimonvat N, Yamoah EN. Lee JH, et al. Among authors: woltz rl. Nat Commun. 2024 Jan 16;15(1):526. doi: 10.1038/s41467-023-44230-x. Nat Commun. 2024. PMID: 38228630 Free PMC article.
Adenylyl cyclase isoform 1 contributes to sinoatrial node automaticity via functional microdomains.
Ren L, Thai PN, Gopireddy RR, Timofeyev V, Ledford HA, Woltz RL, Park S, Puglisi JL, Moreno CM, Santana LF, Conti AC, Kotlikoff MI, Xiang YK, Yarov-Yarovoy V, Zaccolo M, Zhang XD, Yamoah EN, Navedo MF, Chiamvimonvat N. Ren L, et al. Among authors: woltz rl. JCI Insight. 2022 Nov 22;7(22):e162602. doi: 10.1172/jci.insight.162602. JCI Insight. 2022. PMID: 36509290 Free PMC article.
Mechanisms of Calmodulin Regulation of Different Isoforms of Kv7.4 K+ Channels.
Sihn CR, Kim HJ, Woltz RL, Yarov-Yarovoy V, Yang PC, Xu J, Clancy CE, Zhang XD, Chiamvimonvat N, Yamoah EN. Sihn CR, et al. Among authors: woltz rl. J Biol Chem. 2016 Jan 29;291(5):2499-509. doi: 10.1074/jbc.M115.668236. Epub 2015 Oct 29. J Biol Chem. 2016. PMID: 26515070 Free PMC article.
Functional interaction with filamin A and intracellular Ca2+ enhance the surface membrane expression of a small-conductance Ca2+-activated K+ (SK2) channel.
Rafizadeh S, Zhang Z, Woltz RL, Kim HJ, Myers RE, Lu L, Tuteja D, Singapuri A, Bigdeli AA, Harchache SB, Knowlton AA, Yarov-Yarovoy V, Yamoah EN, Chiamvimonvat N. Rafizadeh S, et al. Among authors: woltz rl. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9989-94. doi: 10.1073/pnas.1323541111. Epub 2014 Jun 20. Proc Natl Acad Sci U S A. 2014. PMID: 24951510 Free PMC article.
Adenylyl cyclase subtype-specific compartmentalization: differential regulation of L-type Ca2+ current in ventricular myocytes.
Timofeyev V, Myers RE, Kim HJ, Woltz RL, Sirish P, Heiserman JP, Li N, Singapuri A, Tang T, Yarov-Yarovoy V, Yamoah EN, Hammond HK, Chiamvimonvat N. Timofeyev V, et al. Among authors: woltz rl. Circ Res. 2013 Jun 7;112(12):1567-76. doi: 10.1161/CIRCRESAHA.112.300370. Epub 2013 Apr 22. Circ Res. 2013. PMID: 23609114 Free PMC article.