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Page 1
A framework for conducting GWAS using repeated measures data with an application to childhood BMI.
Burrows K, Heiskala A, Bradfield JP, Balkhiyarova Z, Ning L, Boissel M, Chan YM, Froguel P, Bonnefond A, Hakonarson H, Alves AC, Lawlor DA, Kaakinen M, Järvelin MR, Grant SFA, Tilling K, Prokopenko I, Sebert S, Canouil M, Warrington NM. Burrows K, et al. Among authors: heiskala a. Nat Commun. 2024 Nov 20;15(1):10067. doi: 10.1038/s41467-024-53687-3. Nat Commun. 2024. PMID: 39567492 Free PMC article.
Maternal sex-hormone exposure and the risk of eating disorders in daughters.
Saure E, Sipilä PN, Surcel HM, Latvala A, Heiskala A, Miettunen J, Laasonen M, Lepistö-Paisley T, Raevuori A. Saure E, et al. Among authors: heiskala a. Psychiatry Res. 2024 Dec;342:116170. doi: 10.1016/j.psychres.2024.116170. Epub 2024 Sep 5. Psychiatry Res. 2024. PMID: 39260071 Free article.
Author Correction: Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes.
Bradfeld JP, Kember RL, Ulrich A, Balkhiyarova Z, Alyass A, Aris IM, Bell JA, Broadaway KA, Chen Z, Chai JF, Davies NM, Fernandez-Orth D, Bustamante M, Fore R, Ganguli A, Heiskala A, Hottenga JJ, Íñiguez C, Kobes S, Leinonen J, Lowry E, Lyytikainen LP, Mahajan A, Pitkänen N, Schnurr TM, Have CT, Strachan DP, Thiering E, Vogelezang S, Wade KH, Wang CA, Wong A, Holm LA, Chesi A, Choong C, Cruz M, Elliott P, Franks S, Frithiof-Bøjsøe C, Gauderman WJ, Glessner JT, Gilsanz V, Griesman K, Hanson RL, Kaakinen M, Kalkwarf H, Kelly A, Kindler J, Kähönen M, Lanca C, Lappe J, Lee NR, McCormack S, Mentch FD, Mitchell JA, Mononen N, Niinikoski H, Oken E, Pahkala K, Sim X, Teo YY, Baier LJ, van Beijsterveldt T, Adair LS, Boomsma DI, de Geus E, Guxens M, Eriksson JG, Felix JF, Gilliland FD; Penn Medicine Biobank; Hansen T, Hardy R, Hivert MF, Holm JC, Jaddoe VWV, Järvelin MR, Lehtimäki T, Mackey DA, Meyre D, Mohlke KL, Mykkänen J, Oberfeld S, Pennell CE, Perry JRB, Raitakari O, Rivadeneira F, Saw SM, Sebert S, Shepherd JA, Standl M, Sørensen TIA, Timpson NJ, Torrent M, Willemsen G, Hypponen E, Power C; Early Growth Genetics Consortium; McCarthy MI, Freathy RM, Widén E, Hakonarson H, Proko… See abstract for full author list ➔ Bradfeld JP, et al. Among authors: heiskala a. Genome Biol. 2024 May 21;25(1):129. doi: 10.1186/s13059-024-03276-w. Genome Biol. 2024. PMID: 38773652 Free PMC article. No abstract available.
A framework for conducting time-varying genome-wide association studies: An application to body mass index across childhood in six multiethnic cohorts.
Burrows K, Heiskala A, Bradfield JP, Balkhiyarova Z, Ning L, Boissel M, Chan YM, Froguel P, Bonnefond A, Hakonarson H, Alves AC, Lawlor DA, Kaakinen M, Järvelin MR, Grant SFA, Tilling K, Prokopenko I, Sebert S, Canouil M, Warrington NM. Burrows K, et al. Among authors: heiskala a. medRxiv [Preprint]. 2024 Mar 16:2024.03.13.24304263. doi: 10.1101/2024.03.13.24304263. medRxiv. 2024. PMID: 38559031 Free PMC article. Preprint.
Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes.
Bradfield JP, Kember RL, Ulrich A, Balkhiyarova Z, Alyass A, Aris IM, Bell JA, Broadaway KA, Chen Z, Chai JF, Davies NM, Fernandez-Orth D, Bustamante M, Fore R, Ganguli A, Heiskala A, Hottenga JJ, Íñiguez C, Kobes S, Leinonen J, Lowry E, Lyytikainen LP, Mahajan A, Pitkänen N, Schnurr TM, Have CT, Strachan DP, Thiering E, Vogelezang S, Wade KH, Wang CA, Wong A, Holm LA, Chesi A, Choong C, Cruz M, Elliott P, Franks S, Frithioff-Bøjsøe C, Gauderman WJ, Glessner JT, Gilsanz V, Griesman K, Hanson RL, Kaakinen M, Kalkwarf H, Kelly A, Kindler J, Kähönen M, Lanca C, Lappe J, Lee NR, McCormack S, Mentch FD, Mitchell JA, Mononen N, Niinikoski H, Oken E, Pahkala K, Sim X, Teo YY, Baier LJ, van Beijsterveldt T, Adair LS, Boomsma DI, de Geus E, Guxens M, Eriksson JG, Felix JF, Gilliland FD, Biobank PM, Hansen T, Hardy R, Hivert MF, Holm JC, Jaddoe VWV, Järvelin MR, Lehtimäki T, Mackey DA, Meyre D, Mohlke KL, Mykkänen J, Oberfield S, Pennell CE, Perry JRB, Raitakari O, Rivadeneira F, Saw SM, Sebert S, Shepherd JA, Standl M, Sørensen TIA, Timpson NJ, Torrent M, Willemsen G, Hypponen E, Power C; Early Growth Genetics Consortium; McCarthy MI, Freathy RM, Widén E, Hakonarson H, Prokopenko I,… See abstract for full author list ➔ Bradfield JP, et al. Among authors: heiskala a. Genome Biol. 2024 Jan 16;25(1):22. doi: 10.1186/s13059-023-03136-z. Genome Biol. 2024. PMID: 38229171 Free PMC article.
Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes.
Pervjakova N, Moen GH, Borges MC, Ferreira T, Cook JP, Allard C, Beaumont RN, Canouil M, Hatem G, Heiskala A, Joensuu A, Karhunen V, Kwak SH, Lin FTJ, Liu J, Rifas-Shiman S, Tam CH, Tam WH, Thorleifsson G, Andrew T, Auvinen J, Bhowmik B, Bonnefond A, Delahaye F, Demirkan A, Froguel P, Haller-Kikkatalo K, Hardardottir H, Hummel S, Hussain A, Kajantie E, Keikkala E, Khamis A, Lahti J, Lekva T, Mustaniemi S, Sommer C, Tagoma A, Tzala E, Uibo R, Vääräsmäki M, Villa PM, Birkeland KI, Bouchard L, Duijn CM, Finer S, Groop L, Hämäläinen E, Hayes GM, Hitman GA, Jang HC, Järvelin MR, Jenum AK, Laivuori H, Ma RC, Melander O, Oken E, Park KS, Perron P, Prasad RB, Qvigstad E, Sebert S, Stefansson K, Steinthorsdottir V, Tuomi T, Hivert MF, Franks PW, McCarthy MI, Lindgren CM, Freathy RM, Lawlor DA, Morris AP, Mägi R. Pervjakova N, et al. Among authors: heiskala a. Hum Mol Genet. 2022 Sep 29;31(19):3377-3391. doi: 10.1093/hmg/ddac050. Hum Mol Genet. 2022. PMID: 35220425 Free PMC article.
LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic noncommunicable diseases.
Ronkainen J, Nedelec R, Atehortua A, Balkhiyarova Z, Cascarano A, Ngoc Dang V, Elhakeem A, van Enckevort E, Goncalves Soares A, Haakma S, Halonen M, Heil KF, Heiskala A, Hyde E, Jacquemin B, Keikkala E, Kerckhoffs J, Klåvus A, Kopinska JA, Lepeule J, Marazzi F, Motoc I, Näätänen M, Ribbenstedt A, Rundblad A, Savolainen O, Simonetti V, de Toro Eadie N, Tzala E, Ulrich A, Wright T, Zarei I, d'Amico E, Belotti F, Brunius C, Castleton C, Charles MA, Gaillard R, Hanhineva K, Hoek G, Holven KB, Jaddoe VWV, Kaakinen MA, Kajantie E, Kavousi M, Lakka T, Matthews J, Piano Mortari A, Vääräsmäki M, Voortman T, Webster C, Zins M, Atella V, Bulgheroni M, Chadeau-Hyam M, Conti G, Evans J, Felix JF, Heude B, Järvelin MR, Kolehmainen M, Landberg R, Lekadir K, Parusso S, Prokopenko I, de Rooij SR, Roseboom T, Swertz M, Timpson N, Ulven SM, Vermeulen R, Juola T, Sebert S. Ronkainen J, et al. Among authors: heiskala a. Environ Epidemiol. 2021 Dec 28;6(1):e184. doi: 10.1097/EE9.0000000000000184. eCollection 2022 Feb. Environ Epidemiol. 2021. PMID: 35169663 Free PMC article.
Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the pregnancy and childhood epigenetics consortium.
Ronkainen J, Heiskala A, Vehmeijer FOL, Lowry E, Caramaschi D, Estrada Gutierrez G, Heiss JA, Hummel N, Keikkala E, Kvist T, Kupsco A, Melton PE, Pesce G, Soomro MH, Vives-Usano M, Baiz N, Binder E, Czamara D, Guxens M, Mustaniemi S, London SJ, Rauschert S, Vääräsmäki M, Vrijheid M, Ziegler AG, Annesi-Maesano I, Bustamante M, Huang RC, Hummel S, Just AC, Kajantie E, Lahti J, Lawlor D, Räikkönen K, Järvelin MR, Felix JF, Sebert S. Ronkainen J, et al. Among authors: heiskala a. Epigenetics. 2022 Jan;17(1):19-31. doi: 10.1080/15592294.2020.1864171. Epub 2021 Jan 11. Epigenetics. 2022. PMID: 33331245 Free PMC article.
DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies.
Vehmeijer FOL, Küpers LK, Sharp GC, Salas LA, Lent S, Jima DD, Tindula G, Reese S, Qi C, Gruzieva O, Page C, Rezwan FI, Melton PE, Nohr E, Escaramís G, Rzehak P, Heiskala A, Gong T, Tuominen ST, Gao L, Ross JP, Starling AP, Holloway JW, Yousefi P, Aasvang GM, Beilin LJ, Bergström A, Binder E, Chatzi L, Corpeleijn E, Czamara D, Eskenazi B, Ewart S, Ferre N, Grote V, Gruszfeld D, Håberg SE, Hoyo C, Huen K, Karlsson R, Kull I, Langhendries JP, Lepeule J, Magnus MC, Maguire RL, Molloy PL, Monnereau C, Mori TA, Oken E, Räikkönen K, Rifas-Shiman S, Ruiz-Arenas C, Sebert S, Ullemar V, Verduci E, Vonk JM, Xu CJ, Yang IV, Zhang H, Zhang W, Karmaus W, Dabelea D, Muhlhausler BS, Breton CV, Lahti J, Almqvist C, Jarvelin MR, Koletzko B, Vrijheid M, Sørensen TIA, Huang RC, Arshad SH, Nystad W, Melén E, Koppelman GH, London SJ, Holland N, Bustamante M, Murphy SK, Hivert MF, Baccarelli A, Relton CL, Snieder H, Jaddoe VWV, Felix JF. Vehmeijer FOL, et al. Among authors: heiskala a. Genome Med. 2020 Nov 25;12(1):105. doi: 10.1186/s13073-020-00810-w. Genome Med. 2020. PMID: 33239103 Free PMC article.
Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits.
Vogelezang S, Bradfield JP, Ahluwalia TS, Curtin JA, Lakka TA, Grarup N, Scholz M, van der Most PJ, Monnereau C, Stergiakouli E, Heiskala A, Horikoshi M, Fedko IO, Vilor-Tejedor N, Cousminer DL, Standl M, Wang CA, Viikari J, Geller F, Íñiguez C, Pitkänen N, Chesi A, Bacelis J, Yengo L, Torrent M, Ntalla I, Helgeland Ø, Selzam S, Vonk JM, Zafarmand MH, Heude B, Farooqi IS, Alyass A, Beaumont RN, Have CT, Rzehak P, Bilbao JR, Schnurr TM, Barroso I, Bønnelykke K, Beilin LJ, Carstensen L, Charles MA, Chawes B, Clément K, Closa-Monasterolo R, Custovic A, Eriksson JG, Escribano J, Groen-Blokhuis M, Grote V, Gruszfeld D, Hakonarson H, Hansen T, Hattersley AT, Hollensted M, Hottenga JJ, Hyppönen E, Johansson S, Joro R, Kähönen M, Karhunen V, Kiess W, Knight BA, Koletzko B, Kühnapfel A, Landgraf K, Langhendries JP, Lehtimäki T, Leinonen JT, Li A, Lindi V, Lowry E, Bustamante M, Medina-Gomez C, Melbye M, Michaelsen KF, Morgen CS, Mori TA, Nielsen TRH, Niinikoski H, Oldehinkel AJ, Pahkala K, Panoutsopoulou K, Pedersen O, Pennell CE, Power C, Reijneveld SA, Rivadeneira F, Simpson A, Sly PD, Stokholm J, Teo KK, Thiering E, Timpson NJ, Uitterlinden AG, van Beijsterveldt CEM, van Schaik B… See abstract for full author list ➔ Vogelezang S, et al. Among authors: heiskala a. PLoS Genet. 2020 Oct 12;16(10):e1008718. doi: 10.1371/journal.pgen.1008718. eCollection 2020 Oct. PLoS Genet. 2020. PMID: 33045005 Free PMC article.
18 results