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Bone marrow-derived mesenchymal stromal cells obstruct AML-targeting CD8+ clonal effector and CAR T-cell function while promoting a senescence-associated phenotype.
Towers R, Trombello L, Fusenig M, Tunger A, Baumann AL, Savoldelli R, Wehner R, Fasslrinner F, Arndt C, Dazzi F, Von Bonin M, Feldmann A, Bachmann MP, Wobus M, Schmitz M, Bornhäuser M. Towers R, et al. Among authors: fasslrinner f. Cancer Immunol Immunother. 2024 Jan 17;73(1):8. doi: 10.1007/s00262-023-03594-1. Cancer Immunol Immunother. 2024. PMID: 38231344 Free PMC article.
FLT3-directed UniCAR T-cell therapy of acute myeloid leukaemia.
Peschke JC, Bergmann R, Mehnert M, Gonzalez Soto KE, Loureiro LR, Mitwasi N, Kegler A, Altmann H, Wobus M, Máthé D, Szigeti K, Feldmann A, Bornhäuser M, Bachmann M, Fasslrinner F, Arndt C. Peschke JC, et al. Among authors: fasslrinner f. Br J Haematol. 2023 Sep;202(6):1137-1150. doi: 10.1111/bjh.18971. Epub 2023 Jul 17. Br J Haematol. 2023. PMID: 37460273
UniCAR T cell immunotherapy enables efficient elimination of radioresistant cancer cells.
Arndt C, Loureiro LR, Feldmann A, Jureczek J, Bergmann R, Máthé D, Hegedüs N, Berndt N, Koristka S, Mitwasi N, Fasslrinner F, Lamprecht C, Kegler A, Hoffmann A, Bartsch T, Köseer AS, Egan G, Schmitz M, Hořejší V, Krause M, Dubrovska A, Bachmann M. Arndt C, et al. Among authors: fasslrinner f. Oncoimmunology. 2020 Apr 5;9(1):1743036. doi: 10.1080/2162402X.2020.1743036. eCollection 2020. Oncoimmunology. 2020. PMID: 32426176 Free PMC article.
Targeting Acute Myeloid Leukemia Using the RevCAR Platform: A Programmable, Switchable and Combinatorial Strategy.
Kittel-Boselli E, Soto KEG, Loureiro LR, Hoffmann A, Bergmann R, Arndt C, Koristka S, Mitwasi N, Kegler A, Bartsch T, Berndt N, Altmann H, Fasslrinner F, Bornhäuser M, Bachmann MP, Feldmann A. Kittel-Boselli E, et al. Among authors: fasslrinner f. Cancers (Basel). 2021 Sep 24;13(19):4785. doi: 10.3390/cancers13194785. Cancers (Basel). 2021. PMID: 34638268 Free PMC article.
Radioimmunotherapy in Combination with Reduced-Intensity Conditioning for Allogeneic Hematopoietic Cell Transplantation in Patients with Advanced Multiple Myeloma.
Fasslrinner F, Stölzel F, Kramer M, Teipel R, Brogsitter C, Morgner A, Arndt C, Bachmann M, Hänel M, Röllig C, Kotzerke J, Schetelig J, Bornhäuser M. Fasslrinner F, et al. Biol Blood Marrow Transplant. 2020 Apr;26(4):691-697. doi: 10.1016/j.bbmt.2019.11.007. Epub 2019 Nov 12. Biol Blood Marrow Transplant. 2020. PMID: 31730919 Free article.
Development and Functional Characterization of a Versatile Radio-/Immunotheranostic Tool for Prostate Cancer Management.
Arndt C, Bergmann R, Striese F, Merkel K, Máthé D, Loureiro LR, Mitwasi N, Kegler A, Fasslrinner F, González Soto KE, Neuber C, Berndt N, Kovács N, Szöllősi D, Hegedűs N, Tóth G, Emmermann JP, Harikumar KB, Kovacs T, Bachmann M, Feldmann A. Arndt C, et al. Among authors: fasslrinner f. Cancers (Basel). 2022 Apr 14;14(8):1996. doi: 10.3390/cancers14081996. Cancers (Basel). 2022. PMID: 35454902 Free PMC article.
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