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Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships.
Asquith CRM, East MP, Laitinen T, Alamillo-Ferrer C, Hartikainen E, Wells CI, Axtman AD, Drewry DH, Tizzard GJ, Poso A, Willson TM, Johnson GL. Asquith CRM, et al. Among authors: tizzard gj. bioRxiv [Preprint]. 2023 Dec 28:2023.12.28.573261. doi: 10.1101/2023.12.28.573261. bioRxiv. 2023. Update in: Eur J Med Chem. 2024 May 5;271:116357. doi: 10.1016/j.ejmech.2024.116357. PMID: 38234837 Free PMC article. Updated. Preprint.
Comparison of the structural motifs and packing arrangements of six novel derivatives and one polymorph of 2-(1-phenyl-1H-1,2,3-triazol-4-yl)pyridine.
Tawfiq KM, Miller GJ, Al-Jeboori MJ, Fennell PS, Coles SJ, Tizzard GJ, Wilson C, Potgieter H. Tawfiq KM, et al. Among authors: tizzard gj. Acta Crystallogr B Struct Sci Cryst Eng Mater. 2014 Apr;70(Pt 2):379-89. doi: 10.1107/S2052520614001152. Epub 2014 Mar 28. Acta Crystallogr B Struct Sci Cryst Eng Mater. 2014. PMID: 24675607
Combining Sanford Arylations on Benzodiazepines with the Nuisance Effect.
Khan R, Boonseng S, Kemmitt PD, Felix R, Coles SJ, Tizzard GJ, Williams G, Simmonds O, Harvey JL, Atack J, Cox H, Spencer J. Khan R, et al. Among authors: tizzard gj. Adv Synth Catal. 2017 Sep 18;359(18):3261-3269. doi: 10.1002/adsc.201700626. Epub 2017 Aug 2. Adv Synth Catal. 2017. PMID: 30100832 Free PMC article.
Methyl 4-acet-oxy-2-methyl-2H-1,2-benzothia-zine-3-carboxyl-ate 1,1-dioxide.
Ahmad M, Siddiqui HL, Ahmad S, Irfan Ashiq M, Tizzard GJ. Ahmad M, et al. Among authors: tizzard gj. Acta Crystallogr Sect E Struct Rep Online. 2008 Feb 15;64(Pt 3):o594. doi: 10.1107/S1600536808004029. Acta Crystallogr Sect E Struct Rep Online. 2008. PMID: 21201932 Free PMC article.
95 results