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48 results

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Page 1
Investigation of genetic determinants of cognitive change in later life.
Mahedy L, Anderson EL, Tilling K, Thornton ZA, Elmore AR, Szalma S, Simen A, Culp M, Zicha S, Harel BT, Davey Smith G, Smith EN, Paternoster L. Mahedy L, et al. Among authors: simen a. Transl Psychiatry. 2024 Jan 18;14(1):31. doi: 10.1038/s41398-023-02726-6. Transl Psychiatry. 2024. PMID: 38238328 Free PMC article.
Identifying individuals with non-Alzheimer's disease co-pathologies: A precision medicine approach to clinical trials in sporadic Alzheimer's disease.
Tosun D, Yardibi O, Benzinger TLS, Kukull WA, Masters CL, Perrin RJ, Weiner MW, Simen A, Schwarz AJ; Alzheimer's Disease Neuroimaging Initiative. Tosun D, et al. Among authors: simen a. Alzheimers Dement. 2024 Jan;20(1):421-436. doi: 10.1002/alz.13447. Epub 2023 Sep 4. Alzheimers Dement. 2024. PMID: 37667412 Free PMC article.
An Acetylcholine M1 Receptor-Positive Allosteric Modulator (TAK-071) in Parkinson Disease With Cognitive Impairment: A Phase 2 Randomized Clinical Trial.
Shanbhag NM, Padmanabhan JL, Zhang Z, Harel BT, Jia H, Kangarloo T, Yin W, Dowling AV, Laurenza A, Khudyakov P, Galinsky K, Latzman RD, Simuni T, Weintraub D, Horak FB, Lustig C, Maruff P, Simen AA. Shanbhag NM, et al. Among authors: simen aa. JAMA Neurol. 2025 Jan 6. doi: 10.1001/jamaneurol.2024.4519. Online ahead of print. JAMA Neurol. 2025. PMID: 39761063
Temporal progression of tau pathology and neuroinflammation in a rhesus monkey model of Alzheimer's disease.
Beckman D, Diniz GB, Ott S, Hobson B, Chaudhari AJ, Muller S, Chu Y, Takano A, Schwarz AJ, Yeh CL, McQuade P, Chakrabarty P, Kanaan NM, Quinton MS, Simen AA, Kordower JH, Morrison JH. Beckman D, et al. Among authors: simen aa. Alzheimers Dement. 2024 Aug;20(8):5198-5219. doi: 10.1002/alz.13868. Epub 2024 Jun 21. Alzheimers Dement. 2024. PMID: 39030748 Free PMC article.
Basic clinical features do not predict dopamine transporter binding in idiopathic REM behavior disorder.
Chahine LM, Iranzo A, Fernández-Arcos A, Simuni T, Seedorff N, Caspell-Garcia C, Amara AW, Comella C, Högl B, Hamilton J, Marek K, Mayer G, Mollenhauer B, Postuma R, Tolosa E, Trenkwalder C, Videnovic A, Oertel W; PPMI Sleep Working Group. Chahine LM, et al. NPJ Parkinsons Dis. 2019 Jan 29;5:2. doi: 10.1038/s41531-018-0073-1. eCollection 2019. NPJ Parkinsons Dis. 2019. PMID: 30701189 Free PMC article.
An 8-Week, Randomized, Phase 2, Double-Blind, Sequential Parallel-Group Comparison Study of Two Dose Levels of the GABAA Positive Allosteric Modulator PF-06372865 Compared With Placebo as an Adjunctive Treatment in Outpatients With Inadequate Response to Standard of Care for Generalized Anxiety Disorder.
Simen A, Whitlock M, Qiu R, Miceli J, Zumpano L, Du Metz M, Dua P, Binneman B. Simen A, et al. J Clin Psychopharmacol. 2019 Jan/Feb;39(1):20-27. doi: 10.1097/JCP.0000000000000997. J Clin Psychopharmacol. 2019. PMID: 30531477 Clinical Trial.
48 results