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Triap1 upregulation promotes escape from mitotic-slippage-induced G1 arrest.
Pavani M, Chiroli E, Cancrini C, Gross F, Bonaiuti P, Villa S, Giavazzi F, Matafora V, Bachi A, Fava LL, Lischetti T, Ciliberto A. Pavani M, et al. Among authors: bachi a. Cell Rep. 2023 Mar 28;42(3):112215. doi: 10.1016/j.celrep.2023.112215. Epub 2023 Mar 13. Cell Rep. 2023. PMID: 36917609 Free article.
Clonal cooperation through soluble metabolite exchange facilitates metastatic outgrowth by modulating Allee effect.
Hershey BJ, Barozzi S, Orsenigo F, Pompei S, Iannelli F, Kamrad S, Matafora V, Pisati F, Calabrese L, Fragale G, Salvadori G, Martini E, Totaro MG, Magni S, Guan R, Parazzoli D, Maiuri P, Bachi A, Patil KR, Cosentino Lagomarsino M, Havas KM. Hershey BJ, et al. Among authors: bachi a. Sci Adv. 2023 Sep 15;9(37):eadh4184. doi: 10.1126/sciadv.adh4184. Epub 2023 Sep 15. Sci Adv. 2023. PMID: 37713487 Free PMC article.
Cell stretching activates an ATM mechano-transduction pathway that remodels cytoskeleton and chromatin.
Bastianello G, Porcella G, Beznoussenko GV, Kidiyoor G, Ascione F, Li Q, Cattaneo A, Matafora V, Disanza A, Quarto M, Mironov AA, Oldani A, Barozzi S, Bachi A, Costanzo V, Scita G, Foiani M. Bastianello G, et al. Among authors: bachi a. Cell Rep. 2023 Dec 26;42(12):113555. doi: 10.1016/j.celrep.2023.113555. Epub 2023 Dec 11. Cell Rep. 2023. PMID: 38088930 Free article.
Acetyl-CoA carboxylase 1 controls a lipid droplet-peroxisome axis and is a vulnerability of endocrine-resistant ER+ breast cancer.
Bacci M, Lorito N, Smiriglia A, Subbiani A, Bonechi F, Comito G, Morriset L, El Botty R, Benelli M, López-Velazco JI, Caffarel MM, Urruticoechea A, Sflomos G, Malorni L, Corsini M, Ippolito L, Giannoni E, Meattini I, Matafora V, Havas K, Bachi A, Chiarugi P, Marangoni E, Morandi A. Bacci M, et al. Among authors: bachi a. Sci Transl Med. 2024 Feb 28;16(736):eadf9874. doi: 10.1126/scitranslmed.adf9874. Epub 2024 Feb 28. Sci Transl Med. 2024. PMID: 38416843
Early-onset cancers: Biological bases and clinical implications.
Mauri G, Patelli G, Sartore-Bianchi A, Abrignani S, Bodega B, Marsoni S, Costanzo V, Bachi A, Siena S, Bardelli A. Mauri G, et al. Among authors: bachi a. Cell Rep Med. 2024 Sep 17;5(9):101737. doi: 10.1016/j.xcrm.2024.101737. Epub 2024 Sep 10. Cell Rep Med. 2024. PMID: 39260369 Free PMC article. Review.
SEPN1-related myopathy depends on the oxidoreductase ERO1A and is druggable with the chemical chaperone TUDCA.
Germani S, Van Ho AT, Cherubini A, Varone E, Chernorudskiy A, Renna GM, Fumagalli S, Gobbi M, Lucchetti J, Bolis M, Guarrera L, Craparotta I, Rastelli G, Piccoli G, de Napoli C, Nogara L, Poggio E, Brini M, Cattaneo A, Bachi A, Simmen T, Calì T, Quijano-Roy S, Boncompagni S, Blaauw B, Ferreiro A, Zito E. Germani S, et al. Among authors: bachi a. Cell Rep Med. 2024 Mar 19;5(3):101439. doi: 10.1016/j.xcrm.2024.101439. Epub 2024 Feb 22. Cell Rep Med. 2024. PMID: 38402623 Free PMC article.
322 results