Huang D - Search Results

1

Design, Synthesis, and Biological Evaluation of 2-Substituted Aniline Pyrimidine Derivatives as Potent Dual Mer/c-Met Inhibitors.

Huang D, Chen Y, Yang J, Zhao B, Wang S, Chai T, Cui J, Zhou X, Shang Z. Huang D, et al. Molecules. 2024 Jan 18;29(2):475. doi: 10.3390/molecules29020475. Molecules. 2024. PMID: 38257391 Free PMC article.

2

Amino acid-PEGylated resveratrol and its influence on solubility and the controlled release behavior.

Zhang Y, Song H, Shang Z, Chen A, Huang D, Zhao H, Du H. Zhang Y, et al. Among authors: huang d. Biol Pharm Bull. 2014;37(5):785-93. doi: 10.1248/bpb.b13-00863. Epub 2014 Mar 5. Biol Pharm Bull. 2014. PMID: 24599033 Free article.

3

Structure-guided design and development of novel N-phenylpyrimidin-2-amine derivatives as potential c-Met inhibitors.

Huang D, Yang J, Zhang Q, Wang G, Zhang Z, Zhang Y, Li J. Huang D, et al. Eur J Med Chem. 2021 Nov 5;223:113648. doi: 10.1016/j.ejmech.2021.113648. Epub 2021 Jun 17. Eur J Med Chem. 2021. PMID: 34175535

4

Design, synthesis, and biological evaluation of 2,4-dimorpholinopyrimidine-5-carbonitrile derivatives as orally bioavailable PI3K inhibitors.

Huang D, Yang J, Zhang Q, Zhou X, Wang Y, Shang Z, Li J, Zhang B. Huang D, et al. Front Pharmacol. 2024 Oct 21;15:1467028. doi: 10.3389/fphar.2024.1467028. eCollection 2024. Front Pharmacol. 2024. PMID: 39498341 Free PMC article.

5

Synthesis and biological evaluation of novel 6,11-dihydro-5H-benzo[e]pyrimido- [5,4-b][1,4]diazepine derivatives as potential c-Met inhibitors.

Huang D, Huang L, Zhang Q, Li J. Huang D, et al. Among authors: huang l. Eur J Med Chem. 2017 Nov 10;140:212-228. doi: 10.1016/j.ejmech.2017.08.060. Epub 2017 Sep 14. Eur J Med Chem. 2017. PMID: 28938137

6

Development of Novel IP6K Inhibitors for the Treatment of Obesity and Obesity-Induced Metabolic Dysfunctions.

Zhou Y, Mukherjee S, Huang D, Chakraborty M, Gu C, Zong G, Stashko MA, Pearce KH, Shears SB, Chakraborty A, Wang H, Wang X. Zhou Y, et al. Among authors: huang d. J Med Chem. 2022 May 12;65(9):6869-6887. doi: 10.1021/acs.jmedchem.2c00220. Epub 2022 Apr 25. J Med Chem. 2022. PMID: 35467861 Free PMC article.

7

Application of a MYC degradation screen identifies sensitivity to CDK9 inhibitors in KRAS-mutant pancreatic cancer.

Blake DR, Vaseva AV, Hodge RG, Kline MP, Gilbert TSK, Tyagi V, Huang D, Whiten GC, Larson JE, Wang X, Pearce KH, Herring LE, Graves LM, Frye SV, Emanuele MJ, Cox AD, Der CJ. Blake DR, et al. Among authors: huang d. Sci Signal. 2019 Jul 16;12(590):eaav7259. doi: 10.1126/scisignal.aav7259. Sci Signal. 2019. PMID: 31311847 Free PMC article.

8

Sugemule-7 alleviates oxidative stress, neuroinflammation, and cell death, promoting synaptic plasticity recovery in mice with postpartum depression.

Fu Q, Qiu R, Liang J, Wu S, Huang D, Qin Y, Li Q, Shi X, Xiong X, Jiang Z, Chen Y, Cheng Y. Fu Q, et al. Among authors: huang d. Sci Rep. 2025 Jan 9;15(1):1426. doi: 10.1038/s41598-025-85276-9. Sci Rep. 2025. PMID: 39789071 Free PMC article.

9

Relation between anatomical features of patent foramen ovale and residual shunt based on transesophageal echocardiography.

Mi Z, Li C, He G, Huang D, Zhou X, Gao H, Yang D, Hu Y. Mi Z, et al. Among authors: huang d. Sci Rep. 2025 Jan 9;15(1):1497. doi: 10.1038/s41598-024-82122-2. Sci Rep. 2025. PMID: 39789058 Free PMC article.

10

Impact of p. Gingivalis-induced chronic apical periodontitis on systemic iron homeostasis via the hepatic IL-6/STAT3/Hepcidin signaling pathway.

Zhang J, Chen X, Huang D, Tan X. Zhang J, et al. Among authors: huang d. Int Immunopharmacol. 2025 Jan 7;147:114002. doi: 10.1016/j.intimp.2024.114002. Online ahead of print. Int Immunopharmacol. 2025. PMID: 39787762

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