Chen K - Search Results

1

Yeast EndoG prevents genome instability by degrading cytoplasmic DNA.

Yu Y, Wang X, Fox J, Yu R, Thakre P, McCauley B, Nikoloutsos N, Li Q, Hastings PJ, Dang W, Chen K, Ira G. Yu Y, et al. Among authors: chen k. Res Sq [Preprint]. 2024 Jan 5:rs.3.rs-3641411. doi: 10.21203/rs.3.rs-3641411/v1. Res Sq. 2024. Update in: Nat Commun. 2024 Sep 3;15(1):7653. doi: 10.1038/s41467-024-52147-2 PMID: 38260641 Free PMC article. Updated. Preprint.

2

Dna2 nuclease deficiency results in large and complex DNA insertions at chromosomal breaks.

Yu Y, Pham N, Xia B, Papusha A, Wang G, Yan Z, Peng G, Chen K, Ira G. Yu Y, et al. Among authors: chen k. Nature. 2018 Dec;564(7735):287-290. doi: 10.1038/s41586-018-0769-8. Epub 2018 Dec 5. Nature. 2018. PMID: 30518856 Free PMC article.

3

Yeast EndoG prevents genome instability by degrading extranuclear DNA species.

Yu Y, Wang X, Fox J, Yu R, Thakre P, McCauley B, Nikoloutsos N, Yu Y, Li Q, Hastings PJ, Dang W, Chen K, Ira G. Yu Y, et al. Among authors: chen k. Nat Commun. 2024 Sep 3;15(1):7653. doi: 10.1038/s41467-024-52147-2. Nat Commun. 2024. PMID: 39227600 Free PMC article.

4

Transcriptional inhibition after irradiation occurs preferentially at highly expressed genes in a manner dependent on cell cycle progression.

Chen Z, Wang X, Gao X, Arslanovic N, Chen K, Tyler JK. Chen Z, et al. Among authors: chen k. Elife. 2024 Oct 11;13:RP94001. doi: 10.7554/eLife.94001. Elife. 2024. PMID: 39392398 Free PMC article.

5

RPA and Rad27 limit templated and inverted insertions at DNA breaks.

Yu Y, Wang X, Fox J, Li Q, Yu Y, Hastings PJ, Chen K, Ira G. Yu Y, et al. Among authors: chen k. Nucleic Acids Res. 2025 Jan 7;53(1):gkae1159. doi: 10.1093/nar/gkae1159. Nucleic Acids Res. 2025. PMID: 39673516 Free PMC article.

6

The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends.

Chen X, Cui D, Papusha A, Zhang X, Chu CD, Tang J, Chen K, Pan X, Ira G. Chen X, et al. Among authors: chen k. Nature. 2012 Sep 27;489(7417):576-80. doi: 10.1038/nature11355. Epub 2012 Sep 9. Nature. 2012. PMID: 22960743 Free PMC article.

7

Low RNA stability signifies increased post-transcriptional regulation of cell identity genes.

Li Y, Yi Y, Lv J, Gao X, Yu Y, Babu SS, Bruno I, Zhao D, Xia B, Peng W, Zhu J, Chen H, Zhang L, Cao Q, Chen K. Li Y, et al. Among authors: chen k, chen h. Nucleic Acids Res. 2023 Jul 7;51(12):6020-6038. doi: 10.1093/nar/gkad300. Nucleic Acids Res. 2023. PMID: 37125636 Free PMC article.

8

Embryonic alcohol exposure in zebrafish predisposes adults to cardiomyopathy and diastolic dysfunction.

Weeks O, Gao X, Basu S, Galdieri J, Chen K, Burns CG, Burns CE. Weeks O, et al. Among authors: chen k. Cardiovasc Res. 2024 Nov 5;120(13):1607-1621. doi: 10.1093/cvr/cvae139. Cardiovasc Res. 2024. PMID: 38900908

9

TADsplimer reveals splits and mergers of topologically associating domains for epigenetic regulation of transcription.

Wang G, Meng Q, Xia B, Zhang S, Lv J, Zhao D, Li Y, Wang X, Zhang L, Cooke JP, Cao Q, Chen K. Wang G, et al. Among authors: chen k. Genome Biol. 2020 Apr 2;21(1):84. doi: 10.1186/s13059-020-01992-7. Genome Biol. 2020. PMID: 32241291 Free PMC article.

10

MACMIC Reveals A Dual Role of CTCF in Epigenetic Regulation of Cell Identity Genes.

Wang G, Xia B, Zhou M, Lv J, Zhao D, Li Y, Bu Y, Wang X, Cooke JP, Cao Q, Lee MG, Zhang L, Chen K. Wang G, et al. Among authors: chen k. Genomics Proteomics Bioinformatics. 2021 Feb;19(1):140-153. doi: 10.1016/j.gpb.2020.10.008. Epub 2021 Mar 5. Genomics Proteomics Bioinformatics. 2021. PMID: 33677108 Free PMC article.

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