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Genomics-driven derivatization of the bioactive fungal sesterterpenoid variecolin: Creation of an unnatural analogue with improved anticancer properties.
Yan D, Arakelyan J, Wan T, Raina R, Chan TK, Ahn D, Kushnarev V, Cheung TK, Chan HC, Choi I, Ho PY, Hu F, Kim Y, Lau HL, Law YL, Leung CS, Tong CY, Wong KK, Yim WL, Karnaukhov NS, Kong RYC, Babak MV, Matsuda Y. Yan D, et al. Among authors: kushnarev v. Acta Pharm Sin B. 2024 Jan;14(1):421-432. doi: 10.1016/j.apsb.2023.08.025. Epub 2023 Aug 30. Acta Pharm Sin B. 2024. PMID: 38261827 Free PMC article.
A novel case of glial transdifferentiation in renal medullary carcinoma brain metastasis.
Gubbiotti MA, McCutcheon IE, Rao P, Genovese G, Wang L, Tarasov A, Putintsev V, Berlinski A, Stupichev D, Kriukov K, Davitavyan S, Salem B, Sarachakov A, Lebedev D, Hensley M, Bagaev A, Paradiso F, Kushnarev V, Khegai G, Tannir NM, Msaouel P. Gubbiotti MA, et al. Among authors: kushnarev v. Acta Neuropathol Commun. 2025 Jan 20;13(1):12. doi: 10.1186/s40478-025-01929-w. Acta Neuropathol Commun. 2025. PMID: 39833894
Duvelisib with docetaxel for patients with anti-PD-1 refractory, recurrent or metastatic head and neck squamous cell carcinoma.
Hanna GJ, Oakley LB, Shi R, ONeill A, Shin KY, Scarfo N, Sehgal K, Dennis MJ, Quinn N, Jo VY, Wong K, Shvyrkova A, Kushnarev V, Shanthappa BU, Tkachuk A, Kryukov K, Sarachakov A, Svekolkin V, Lennerz J, Waters S, Haddad RI. Hanna GJ, et al. Among authors: kushnarev v. Clin Cancer Res. 2024 Dec 3. doi: 10.1158/1078-0432.CCR-24-2262. Online ahead of print. Clin Cancer Res. 2024. PMID: 39625478
Response-Adaptive Surgical Timing in neoadjuvant immunotherapy demonstrates enhanced pathologic treatment response in Head and Neck Squamous Cell Carcinoma.
Mastrolonardo EV, Nunes KL, Llerena P, Nikitina A, Sobol A, Scott ER, Tuluc M, Davitt CJH, Scher J, Tekumalla S, Mann D, Henao C, Jegede V, Gargano S, Harshyne LA, Alnemri A, Tyshevich A, Kushnarev V, Chasse M, Sookiasian D, Axelrod R, Zhan T, Leiby BE, Old M, Seim N, Mahoney MG, Martinez-Outschoorn U, Cognetti DM, Curry JM, Prendergast G, Argiris A, South AP, Linnenbach AJ, Johnson JM, Luginbuhl AJ. Mastrolonardo EV, et al. Among authors: kushnarev v. Clin Cancer Res. 2024 Nov 25. doi: 10.1158/1078-0432.CCR-24-0037. Online ahead of print. Clin Cancer Res. 2024. PMID: 39585339
Interfering with Metabolic Profile of Triple-Negative Breast Cancers Using Rationally Designed Metformin Prodrugs.
Babak MV, Chong KR, Rapta P, Zannikou M, Tang HM, Reichert L, Chang MR, Kushnarev V, Heffeter P, Meier-Menches SM, Lim ZC, Yap JY, Casini A, Balyasnikova IV, Ang WH. Babak MV, et al. Among authors: kushnarev v. Angew Chem Int Ed Engl. 2021 Jun 7;60(24):13405-13413. doi: 10.1002/anie.202102266. Epub 2021 May 6. Angew Chem Int Ed Engl. 2021. PMID: 33755286
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