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126 results

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Page 1
Metabolic heterogeneity in cancer.
Demicco M, Liu XZ, Leithner K, Fendt SM. Demicco M, et al. Among authors: fendt sm. Nat Metab. 2024 Jan;6(1):18-38. doi: 10.1038/s42255-023-00963-z. Epub 2024 Jan 24. Nat Metab. 2024. PMID: 38267631 Review.
More Metabolism!
Olzmann JA, Fendt SM, Shah YM, Vousden K, Chandel N, Horng T, Danial N, Tu B, Christofk H, Vander Heiden MG, Wellen K. Olzmann JA, et al. Among authors: fendt sm. Mol Cell. 2021 Sep 16;81(18):3659-3664. doi: 10.1016/j.molcel.2021.08.040. Mol Cell. 2021. PMID: 34547228 Free article.
Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism.
Fendt SM, Bell EL, Keibler MA, Davidson SM, Wirth GJ, Fiske B, Mayers JR, Schwab M, Bellinger G, Csibi A, Patnaik A, Blouin MJ, Cantley LC, Guarente L, Blenis J, Pollak MN, Olumi AF, Vander Heiden MG, Stephanopoulos G. Fendt SM, et al. Cancer Res. 2013 Jul 15;73(14):4429-38. doi: 10.1158/0008-5472.CAN-13-0080. Epub 2013 May 17. Cancer Res. 2013. PMID: 23687346 Free PMC article.
Metastasis.
Lyden D, Ghajar CM, Correia AL, Aguirre-Ghiso JA, Cai S, Rescigno M, Zhang P, Hu G, Fendt SM, Boire A, Weichselbaum RR, Katipally RR. Lyden D, et al. Among authors: fendt sm. Cancer Cell. 2022 Aug 8;40(8):787-791. doi: 10.1016/j.ccell.2022.07.010. Cancer Cell. 2022. PMID: 35944497 Free PMC article.
The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4.
Csibi A, Fendt SM, Li C, Poulogiannis G, Choo AY, Chapski DJ, Jeong SM, Dempsey JM, Parkhitko A, Morrison T, Henske EP, Haigis MC, Cantley LC, Stephanopoulos G, Yu J, Blenis J. Csibi A, et al. Among authors: fendt sm. Cell. 2021 Apr 15;184(8):2256. doi: 10.1016/j.cell.2021.03.059. Cell. 2021. PMID: 33861966 Free article. No abstract available.
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity.
Vriens K, Christen S, Parik S, Broekaert D, Yoshinaga K, Talebi A, Dehairs J, Escalona-Noguero C, Schmieder R, Cornfield T, Charlton C, Romero-Pérez L, Rossi M, Rinaldi G, Orth MF, Boon R, Kerstens A, Kwan SY, Faubert B, Méndez-Lucas A, Kopitz CC, Chen T, Fernandez-Garcia J, Duarte JAG, Schmitz AA, Steigemann P, Najimi M, Hägebarth A, Van Ginderachter JA, Sokal E, Gotoh N, Wong KK, Verfaillie C, Derua R, Munck S, Yuneva M, Beretta L, DeBerardinis RJ, Swinnen JV, Hodson L, Cassiman D, Verslype C, Christian S, Grünewald S, Grünewald TGP, Fendt SM. Vriens K, et al. Among authors: fendt sm. Nature. 2019 Feb;566(7744):403-406. doi: 10.1038/s41586-019-0904-1. Epub 2019 Feb 6. Nature. 2019. PMID: 30728499 Free PMC article.
Breast cancer cells rely on environmental pyruvate to shape the metastatic niche.
Elia I, Rossi M, Stegen S, Broekaert D, Doglioni G, van Gorsel M, Boon R, Escalona-Noguero C, Torrekens S, Verfaillie C, Verbeken E, Carmeliet G, Fendt SM. Elia I, et al. Among authors: fendt sm. Nature. 2019 Apr;568(7750):117-121. doi: 10.1038/s41586-019-0977-x. Epub 2019 Feb 27. Nature. 2019. PMID: 30814728 Free PMC article.
126 results