Brown J - Search Results

1

Dietary tryptophan and genetic susceptibility expand gut microbiota that promote systemic autoimmune activation.

Ma L, Ge Y, Brown J, Choi SC, Elshikha A, Kanda N, Terrell M, Six N, Garcia A, Mohamadzadeh M, Silverman G, Morel L. Ma L, et al. Among authors: brown j. bioRxiv [Preprint]. 2024 Jan 19:2024.01.16.575942. doi: 10.1101/2024.01.16.575942. bioRxiv. 2024. PMID: 38293097 Free PMC article. Preprint.

2

TLR7/TLR8 activation and susceptibility genes synergize to breach gut barrier in a mouse model of lupus.

Ma L, Terrell M, Brown J, Castellanos Garcia A, Elshikha A, Morel L. Ma L, et al. Among authors: brown j. Front Immunol. 2023 Jul 6;14:1187145. doi: 10.3389/fimmu.2023.1187145. eCollection 2023. Front Immunol. 2023. PMID: 37483626 Free PMC article.

3

Gut microbiota dysbiosis and altered tryptophan catabolism contribute to autoimmunity in lupus-susceptible mice.

Choi SC, Brown J, Gong M, Ge Y, Zadeh M, Li W, Croker BP, Michailidis G, Garrett TJ, Mohamadzadeh M, Morel L. Choi SC, et al. Among authors: brown j. Sci Transl Med. 2020 Jul 8;12(551):eaax2220. doi: 10.1126/scitranslmed.aax2220. Sci Transl Med. 2020. PMID: 32641487 Free PMC article.

4

Microbiota-mediated skewing of tryptophan catabolism modulates CD4⁺ T cells in lupus-prone mice.

Brown J, Abboud G, Ma L, Choi SC, Kanda N, Zeumer-Spataro L, Lee J, Peng W, Cagmat J, Faludi T, Mohamadzadeh M, Garrett T, Mandik-Nayak L, Chervonsky A, Perl A, Morel L. Brown J, et al. iScience. 2022 Apr 12;25(5):104241. doi: 10.1016/j.isci.2022.104241. eCollection 2022 May 20. iScience. 2022. PMID: 35494242 Free PMC article.

5

Pharmacologic inhibition of glycolysis prevents the development of lupus by altering the gut microbiome in mice.

Elshikha AS, Ge Y, Brown J, Kanda N, Zadeh M, Abboud G, Choi SC, Silverman G, Garrett TJ, Clapp WL, Mohamadzadeh M, Morel L. Elshikha AS, et al. Among authors: brown j. iScience. 2023 Jun 14;26(7):107122. doi: 10.1016/j.isci.2023.107122. eCollection 2023 Jul 21. iScience. 2023. PMID: 37416482 Free PMC article.

6

Intestinal Dysbiosis and Tryptophan Metabolism in Autoimmunity.

Brown J, Robusto B, Morel L. Brown J, et al. Front Immunol. 2020 Aug 4;11:1741. doi: 10.3389/fimmu.2020.01741. eCollection 2020. Front Immunol. 2020. PMID: 32849620 Free PMC article. Review.

7

Lupus susceptibility gene Esrrg modulates regulatory T cells through mitochondrial metabolism.

Li W, Gong M, Park YP, Elshikha AS, Choi SC, Brown J, Kanda N, Yeh WI, Peters L, Titov AA, Teng X, Brusko TM, Morel L. Li W, et al. Among authors: brown j. JCI Insight. 2021 Jul 22;6(14):e143540. doi: 10.1172/jci.insight.143540. JCI Insight. 2021. PMID: 34156979 Free PMC article.

8

T cells expressing the lupus susceptibility allele Pbx1d enhance autoimmunity and atherosclerosis in dyslipidemic mice.

Li W, Elshikha AS, Cornaby C, Teng X, Abboud G, Brown J, Zou X, Zeumer-Spataro L, Robusto B, Choi SC, Fredenburg K, Major A, Morel L. Li W, et al. Among authors: brown j. JCI Insight. 2020 Jun 4;5(11):e138274. doi: 10.1172/jci.insight.138274. JCI Insight. 2020. PMID: 32493841 Free PMC article.

9

Redox Homeostasis Involvement in the Pharmacological Effects of Metformin in Systemic Lupus Erythematosus.

Teng X, Brown J, Morel L. Teng X, et al. Among authors: brown j. Antioxid Redox Signal. 2022 Mar;36(7-9):462-479. doi: 10.1089/ars.2021.0070. Epub 2022 Jan 4. Antioxid Redox Signal. 2022. PMID: 34619975 Free PMC article. Review.

10

Metabolic determinants of lupus pathogenesis.

Teng X, Brown J, Choi SC, Li W, Morel L. Teng X, et al. Among authors: brown j. Immunol Rev. 2020 May;295(1):167-186. doi: 10.1111/imr.12847. Epub 2020 Mar 12. Immunol Rev. 2020. PMID: 32162304 Free PMC article. Review.

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