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Page 1
Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis.
Horisberger A, Griffith A, Keegan J, Arazi A, Pulford J, Murzin E, Howard K, Hancock B, Fava A, Sasaki T, Ghosh T, Inamo J, Beuschel R, Cao Y, Preisinger K, Gutierrez-Arcelus M, Eisenhaure TM, Guthridge J, Hoover PJ, Dall'Era M, Wofsy D, Kamen DL, Kalunian KC, Furie R, Belmont M, Izmirly P, Clancy R, Hildeman D, Woodle ES, Apruzzese W, McMahon MA, Grossman J, Barnas JL, Payan-Schober F, Ishimori M, Weisman M, Kretzler M, Berthier CC, Hodgin JB, Demeke DS, Putterman C; Accelerating Medicines Partnership: RA/SLE Network; Brenner MB, Anolik JH, Raychaudhuri S, Hacohen N, James JA, Davidson A, Petri MA, Buyon JP, Diamond B, Zhang F, Lederer JA, Rao DA. Horisberger A, et al. Among authors: howard k. bioRxiv [Preprint]. 2024 Mar 9:2024.01.14.575609. doi: 10.1101/2024.01.14.575609. bioRxiv. 2024. PMID: 38293222 Free PMC article. Preprint.
Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis.
Inamo J, Keegan J, Griffith A, Ghosh T, Horisberger A, Howard K, Pulford J, Murzin E, Hancock B, Jonsson AH, Seifert J, Feser ML, Norris JM, Cao Y, Apruzzese W, Louis Bridges S, Bykerk V, Goodman S, Donlin L, Firestein GS, Perlman H, Bathon JM, Hughes LB, Tabechian D, Filer A, Pitzalis C, Anolik JH, Moreland L, Guthridge JM, James JA, Brenner MB, Raychaudhuri S, Sparks JA; Accelerating Medicines Partnership RA/SLE Network; Michael Holers V, Deane KD, Lederer JA, Rao DA, Zhang F. Inamo J, et al. Among authors: howard k. bioRxiv [Preprint]. 2023 Jul 4:2023.07.03.547507. doi: 10.1101/2023.07.03.547507. bioRxiv. 2023. PMID: 37461737 Free PMC article. Preprint.
High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership.
Carlucci PM, Li J, Fava A, Deonaraine KK, Wofsy D, James JA, Putterman C, Diamond B, Davidson A, Fine DM, Monroy-Trujillo J, Atta MG, DeJager W, Guthridge JM, Haag K, Rao DA, Brenner MB, Lederer JA, Apruzzese W, Belmont HM, Izmirly PM, Zaminski D, Wu M, Connery S, Payan-Schober F, Furie R, Dall'Era M, Cho K, Kamen D, Kalunian K, Anolik J, Barnas J, Ishimori M, Weisman MH; Accelerating Medicines Partnership (AMP) RA/SLE Network; Buyon JP, Petri M. Carlucci PM, et al. Rheumatology (Oxford). 2022 Nov 2;61(11):4335-4343. doi: 10.1093/rheumatology/keac067. Rheumatology (Oxford). 2022. PMID: 35212719 Free PMC article.
Mechanisms Driving Neutrophil-Induced T-cell Immunoparalysis in Ovarian Cancer.
Emmons TR, Giridharan T, Singel KL, Khan ANH, Ricciuti J, Howard K, Silva-Del Toro SL, Debreceni IL, Aarts CEM, Brouwer MC, Suzuki S, Kuijpers TW, Jongerius I, Allen LH, Ferreira VP, Schubart A, Sellner H, Eder J, Holland SM, Ram S, Lederer JA, Eng KH, Moysich KB, Odunsi K, Yaffe MB, Zsiros E, Segal BH. Emmons TR, et al. Among authors: howard k. Cancer Immunol Res. 2021 Jul;9(7):790-810. doi: 10.1158/2326-6066.CIR-20-0922. Epub 2021 May 14. Cancer Immunol Res. 2021. PMID: 33990375 Free PMC article.
Targeted Next-Generation Sequencing of Cell-Free DNA to Detect MYC-Immunoglobulin Translocation and Epstein-Barr Virus DNA in Plasma of Burkitt Lymphoma Patients in East Africa.
Chamba C, Jennings D, Shungu R, Christopher H, Josephat E, Howard K, Dreau H, Burns A, Mawalla W, Mapendo P, Mnango L, Legason I, Elias E, Achola C, Cutts A, Balandya E, Schuh A; AI-REAL Consortium. Chamba C, et al. Among authors: howard k. JCO Glob Oncol. 2025 Jan;11:e2400210. doi: 10.1200/GO.24.00210. Epub 2025 Jan 9. JCO Glob Oncol. 2025. PMID: 39787450
Multimodal cell-free DNA whole-genome TAPS is sensitive and reveals specific cancer signals.
Vavoulis DV, Cutts A, Thota N, Brown J, Sugar R, Rueda A, Ardalan A, Howard K, Matos Santo F, Sannasiddappa T, Miller B, Ash S, Liu Y, Song CX, Nicholson BD, Dreau H, Tregidgo C, Schuh A. Vavoulis DV, et al. Among authors: howard k. Nat Commun. 2025 Jan 8;16(1):430. doi: 10.1038/s41467-024-55428-y. Nat Commun. 2025. PMID: 39779727 Free PMC article.
1,248 results