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Identification of druggable host dependency factors shared by multiple SARS-CoV-2 variants of concern.
Frasson I, Diamante L, Zangrossi M, Carbognin E, Pietà AD, Penna A, Rosato A, Verin R, Torrigiani F, Salata C, Dizanzo MP, Vaccaro L, Cacchiarelli D, Richter SN, Montagner M, Martello G. Frasson I, et al. Among authors: vaccaro l. J Mol Cell Biol. 2024 Aug 26;16(3):mjae004. doi: 10.1093/jmcb/mjae004. J Mol Cell Biol. 2024. PMID: 38305139 Free PMC article.
Automatic identification of small molecules that promote cell conversion and reprogramming.
Napolitano F, Rapakoulia T, Annunziata P, Hasegawa A, Cardon M, Napolitano S, Vaccaro L, Iuliano A, Wanderlingh LG, Kasukawa T, Medina DL, Cacchiarelli D, Gao X, di Bernardo D, Arner E. Napolitano F, et al. Among authors: vaccaro l. Stem Cell Reports. 2021 May 11;16(5):1381-1390. doi: 10.1016/j.stemcr.2021.03.028. Epub 2021 Apr 22. Stem Cell Reports. 2021. PMID: 33891873 Free PMC article.
Heterozygous variants disrupting the interaction of ERF with activated ERK1/2 cause microcephaly, developmental delay, and skeletal anomalies.
Micale L, Vourlia A, Fusco C, Pracella R, Karagiannis DC, Nardella G, Vaccaro L, Leone MP, Gramazio A, Dentici ML, Aiello C, Novelli A, Xenou L, Sui Y, Eichler EE, Cacchiarelli D, Mavrothalassitis G, Castori M. Micale L, et al. Among authors: vaccaro l. Eur J Hum Genet. 2024 Dec 12. doi: 10.1038/s41431-024-01721-9. Online ahead of print. Eur J Hum Genet. 2024. PMID: 39668184
Integrated exome and transcriptome analysis prioritizes MAP4K4 de novo frameshift variants in autism spectrum disorder as a novel disease-gene association.
Cesana M, Vaccaro L, Larsen MJ, Kibæk M, Micale L, Riccardo S, Annunziata P, Colantuono C, Di Filippo L, De Brasi D, Castori M, Fagerberg C, Acquaviva F, Cacchiarelli D. Cesana M, et al. Among authors: vaccaro l. Hum Genet. 2023 Mar;142(3):343-350. doi: 10.1007/s00439-022-02497-y. Epub 2022 Dec 5. Hum Genet. 2023. PMID: 36469137 Free PMC article.
Cellular population dynamics shape the route to human pluripotency.
Panariello F, Gagliano O, Luni C, Grimaldi A, Angiolillo S, Qin W, Manfredi A, Annunziata P, Slovin S, Vaccaro L, Riccardo S, Bouche V, Dionisi M, Salvi M, Martewicz S, Hu M, Cui M, Stuart H, Laterza C, Baruzzo G, Schiebinger G, Di Camillo B, Cacchiarelli D, Elvassore N. Panariello F, et al. Among authors: vaccaro l. Nat Commun. 2023 May 17;14(1):2829. doi: 10.1038/s41467-023-37270-w. Nat Commun. 2023. PMID: 37198156 Free PMC article.
Excitatory Cortical Neurons from CDKL5 Deficiency Disorder Patient-Derived Organoids Show Early Hyperexcitability Not Identified in Neurogenin2 Induced Neurons.
Glass MR, Whye D, Anderson NC, Wood D, Makhortova NR, Polanco T, Kim KH, Donovan KE, Vaccaro L, Jain A, Cacchiarelli D, Sun L, Olson H, Buttermore ED, Sahin M. Glass MR, et al. Among authors: vaccaro l. bioRxiv [Preprint]. 2024 Nov 11:2024.11.11.622878. doi: 10.1101/2024.11.11.622878. bioRxiv. 2024. PMID: 39605742 Free PMC article. Preprint.
161 results