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Page 1
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior.
Solidoro R, Miciaccia M, Bonaccorso C, Fortuna CG, Armenise D, Centonze A, Ferorelli S, Vitale P, Rodrigues P, Guimarães R, de Oliveira A, da Paz M, Rangel L, Sathler PC, Altomare A, Perrone MG, Scilimati A. Solidoro R, et al. Among authors: sathler pc. Eur J Med Chem. 2024 Feb 15;266:116135. doi: 10.1016/j.ejmech.2024.116135. Epub 2024 Jan 10. Eur J Med Chem. 2024. PMID: 38219659
Enzymatic synthesis of ascorbyl oleate and evaluation of biological activities.
Costa KAD, Catarina AS, Leal ICR, Sathler PC, de Oliveira D, de Oliveira AASC, Cansian RL, Dallago RM, Zeni J, Paroul N. Costa KAD, et al. Among authors: sathler pc. Food Res Int. 2022 Nov;161:111851. doi: 10.1016/j.foodres.2022.111851. Epub 2022 Aug 27. Food Res Int. 2022. PMID: 36192978
Development of rivaroxaban microemulsion-based hydrogel for transdermal treatment and prevention of venous thromboembolism.
Araújo CDCB, Simon A, Honório TDS, da Silva SVC, Valle IMM, da Silva LCRP, Rodrigues CR, de Sousa VP, Cabral LM, Sathler PC, do Carmo FA. Araújo CDCB, et al. Among authors: sathler pc. Colloids Surf B Biointerfaces. 2021 Oct;206:111978. doi: 10.1016/j.colsurfb.2021.111978. Epub 2021 Jul 16. Colloids Surf B Biointerfaces. 2021. PMID: 34293580
Novel rivaroxaban-loaded poly(lactic-co-glycolic acid)/poloxamer nanoparticles: preparation, physicochemical characterization, in vitro evaluation of time-dependent anticoagulant activity and toxicological profile.
Machado ME, de Souza Furtado P, da Costa Bernardes Araújo C, Simon A, de Moraes MC, Rodrigues Pereira da Silva LC, do Carmo FA, Cabral LM, Sathler PC. Machado ME, et al. Among authors: sathler pc. Nanotechnology. 2021 Mar 26;32(13):135101. doi: 10.1088/1361-6528/abd0b5. Nanotechnology. 2021. PMID: 33276347
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid.
Perrone MG, Miciaccia M, Vitale P, Ferorelli S, Araújo CDCB, de Almeida GS, Souza Domingos TF, da Silva LCRP, de Pádula M, Cabral LM, Sathler PC, Bonaccorso C, Fortuna CG, Scilimati A. Perrone MG, et al. Among authors: sathler pc. Eur J Med Chem. 2021 Jan 1;209:112919. doi: 10.1016/j.ejmech.2020.112919. Epub 2020 Oct 9. Eur J Med Chem. 2021. PMID: 33129592
Hemostatic abnormalities in COVID-19: A guided review.
Sathler PC. Sathler PC. An Acad Bras Cienc. 2020;92(4):e20200834. doi: 10.1590/0001-3765202020200834. Epub 2020 Aug 24. An Acad Bras Cienc. 2020. PMID: 32844987 Free article. Review.
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability.
Pati ML, Vitale P, Ferorelli S, Iaselli M, Miciaccia M, Boccarelli A, Di Mauro GD, Fortuna CG, Souza Domingos TF, Rodrigues Pereira da Silva LC, de Pádula M, Cabral LM, Sathler PC, Vacca A, Scilimati A, Perrone MG. Pati ML, et al. Among authors: sathler pc. Eur J Med Chem. 2019 Feb 15;164:59-76. doi: 10.1016/j.ejmech.2018.12.029. Epub 2018 Dec 15. Eur J Med Chem. 2019. PMID: 30590258
30 results