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Page 1
Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair.
Kokic G, Yakoub G, van den Heuvel D, Wondergem AP, van der Meer PJ, van der Weegen Y, Chernev A, Fianu I, Fokkens TJ, Lorenz S, Urlaub H, Cramer P, Luijsterburg MS. Kokic G, et al. Among authors: van der weegen y. Nat Struct Mol Biol. 2024 Mar;31(3):536-547. doi: 10.1038/s41594-023-01207-0. Epub 2024 Feb 5. Nat Struct Mol Biol. 2024. PMID: 38316879 Free PMC article.
ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation.
van der Weegen Y, de Lint K, van den Heuvel D, Nakazawa Y, Mevissen TET, van Schie JJM, San Martin Alonso M, Boer DEC, González-Prieto R, Narayanan IV, Klaassen NHM, Wondergem AP, Roohollahi K, Dorsman JC, Hara Y, Vertegaal ACO, de Lange J, Walter JC, Noordermeer SM, Ljungman M, Ogi T, Wolthuis RMF, Luijsterburg MS. van der Weegen Y, et al. Nat Cell Biol. 2021 Jun;23(6):595-607. doi: 10.1038/s41556-021-00688-9. Epub 2021 Jun 9. Nat Cell Biol. 2021. PMID: 34108663 Free PMC article.
Transcription-Coupled DNA Repair: From Mechanism to Human Disorder.
van den Heuvel D, van der Weegen Y, Boer DEC, Ogi T, Luijsterburg MS. van den Heuvel D, et al. Among authors: van der weegen y. Trends Cell Biol. 2021 May;31(5):359-371. doi: 10.1016/j.tcb.2021.02.007. Epub 2021 Mar 5. Trends Cell Biol. 2021. PMID: 33685798 Review.
A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair.
van den Heuvel D, Spruijt CG, González-Prieto R, Kragten A, Paulsen MT, Zhou D, Wu H, Apelt K, van der Weegen Y, Yang K, Dijk M, Daxinger L, Marteijn JA, Vertegaal ACO, Ljungman M, Vermeulen M, Luijsterburg MS. van den Heuvel D, et al. Among authors: van der weegen y. Nat Commun. 2021 Feb 26;12(1):1342. doi: 10.1038/s41467-021-21520-w. Nat Commun. 2021. PMID: 33637760 Free PMC article.
Mono-ubiquitination of Rabphilin 3A by UBE3A serves a non-degradative function.
Avagliano Trezza R, Punt AM, Mientjes E, van den Berg M, Zampeta FI, de Graaf IJ, van der Weegen Y, Demmers JAA, Elgersma Y, Distel B. Avagliano Trezza R, et al. Among authors: van der weegen y. Sci Rep. 2021 Feb 4;11(1):3007. doi: 10.1038/s41598-021-82319-9. Sci Rep. 2021. PMID: 33542309 Free PMC article.
Transcription-coupled nucleotide excision repair is coordinated by ubiquitin and SUMO in response to ultraviolet irradiation.
Liebelt F, Schimmel J, Verlaan-de Vries M, Klemann E, van Royen ME, van der Weegen Y, Luijsterburg MS, Mullenders LH, Pines A, Vermeulen W, Vertegaal ACO. Liebelt F, et al. Among authors: van der weegen y. Nucleic Acids Res. 2020 Jan 10;48(1):231-248. doi: 10.1093/nar/gkz977. Nucleic Acids Res. 2020. PMID: 31722399 Free PMC article.
TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A.
Pines A, Dijk M, Makowski M, Meulenbroek EM, Vrouwe MG, van der Weegen Y, Baltissen M, French PJ, van Royen ME, Luijsterburg MS, Mullenders LH, Vermeulen M, Vermeulen W, Pannu NS, van Attikum H. Pines A, et al. Among authors: van der weegen y. Nat Commun. 2018 Mar 12;9(1):1040. doi: 10.1038/s41467-018-03484-6. Nat Commun. 2018. PMID: 29531219 Free PMC article.
A Comparative Study of SMN Protein and mRNA in Blood and Fibroblasts in Patients with Spinal Muscular Atrophy and Healthy Controls.
Wadman RI, Stam M, Jansen MD, van der Weegen Y, Wijngaarde CA, Harschnitz O, Sodaar P, Braun KP, Dooijes D, Lemmink HH, van den Berg LH, van der Pol WL. Wadman RI, et al. Among authors: van der weegen y. PLoS One. 2016 Nov 28;11(11):e0167087. doi: 10.1371/journal.pone.0167087. eCollection 2016. PLoS One. 2016. PMID: 27893852 Free PMC article. Clinical Trial.