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ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97.
Pozner A, Li L, Verma SP, Wang S, Barrott JJ, Nelson ML, Yu JSE, Negri GL, Colborne S, Hughes CS, Zhu JF, Lambert SL, Carroll LS, Smith-Fry K, Stewart MG, Kannan S, Jensen B, John CM, Sikdar S, Liu H, Dang NH, Bourdage J, Li J, Vahrenkamp JM, Mortenson KL, Groundland JS, Wustrack R, Senger DL, Zemp FJ, Mahoney DJ, Gertz J, Zhang X, Lazar AJ, Hirst M, Morin GB, Nielsen TO, Shen PS, Jones KB. Pozner A, et al. Among authors: gertz j. Nat Commun. 2024 Feb 7;15(1):1165. doi: 10.1038/s41467-024-45280-5. Nat Commun. 2024. PMID: 38326311 Free PMC article.
Cis-regulatory control of transcriptional timing and noise in response to estrogen.
Ginley-Hidinger M, Abewe H, Osborne K, Richey A, Kitchen N, Mortenson KL, Wissink EM, Lis J, Zhang X, Gertz J. Ginley-Hidinger M, et al. Among authors: gertz j. bioRxiv [Preprint]. 2024 Feb 14:2023.03.14.532457. doi: 10.1101/2023.03.14.532457. bioRxiv. 2024. Update in: Cell Genom. 2024 May 8;4(5):100542. doi: 10.1016/j.xgen.2024.100542 PMID: 36993565 Free PMC article. Updated. Preprint.
ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97.
Pozner A, Verma SP, Li L, Wang S, Barrott JJ, Nelson ML, Yu JSE, Negri GL, Colborne S, Hughes CS, Zhu JF, Lambert SL, Carroll LS, Smith-Fry K, Stewart MG, Kannan S, Jensen B, Mortenson KL, John C, Sikdar S, Liu H, Dang NH, Bourdage J, Li J, Vahrenkamp JM, Groundland JS, Wustrack R, Senger DL, Zemp FJ, Mahoney DJ, Gertz J, Zhang X, Lazar AJ, Hirst M, Morin GB, Nielsen TO, Shen PS, Jones KB. Pozner A, et al. Among authors: gertz j. bioRxiv [Preprint]. 2023 Oct 2:2023.09.29.560242. doi: 10.1101/2023.09.29.560242. bioRxiv. 2023. Update in: Nat Commun. 2024 Feb 7;15(1):1165. doi: 10.1038/s41467-024-45280-5 PMID: 37873234 Free PMC article. Updated. Preprint.
3D genomic analysis reveals novel enhancer-hijacking caused by complex structural alterations that drive oncogene overexpression.
Mortenson KL, Dawes C, Wilson ER, Patchen NE, Johnson HE, Gertz J, Bailey SD, Liu Y, Varley KE, Zhang X. Mortenson KL, et al. Among authors: gertz j. bioRxiv [Preprint]. 2024 Jun 21:2024.01.23.576965. doi: 10.1101/2024.01.23.576965. bioRxiv. 2024. Update in: Nat Commun. 2024 Jul 20;15(1):6130. doi: 10.1038/s41467-024-50387-w PMID: 38328209 Free PMC article. Updated. Preprint.
Cis-regulatory control of transcriptional timing and noise in response to estrogen.
Ginley-Hidinger M, Abewe H, Osborne K, Richey A, Kitchen N, Mortenson KL, Wissink EM, Lis J, Zhang X, Gertz J. Ginley-Hidinger M, et al. Among authors: gertz j. Cell Genom. 2024 May 8;4(5):100542. doi: 10.1016/j.xgen.2024.100542. Epub 2024 Apr 24. Cell Genom. 2024. PMID: 38663407 Free PMC article.
The EstroGene2.0 database for endocrine therapy response and resistance in breast cancer.
Li Z, Chen F, Chen L, Liu J, Tseng D, Hadi F, Omarjee S, Kishore K, Kent J, Kirkpatrick J, D'Santos C, Lawson M, Gertz J, Sikora MJ, McDonnell DP, Carroll JS, Polyak K, Oesterreich S, Lee AV. Li Z, et al. Among authors: gertz j. NPJ Breast Cancer. 2024 Dec 19;10(1):106. doi: 10.1038/s41523-024-00709-4. NPJ Breast Cancer. 2024. PMID: 39702552 Free PMC article.
EstroGene2.0: A multi-omic database of response to estrogens, ER-modulators, and resistance to endocrine therapies in breast cancer.
Li Z, Chen F, Chen L, Liu J, Tseng D, Hadi F, Omarjee S, Kishore K, Kent J, Kirkpatrick J, D'Santos C, Lawson M, Gertz J, Sikora MJ, McDonnell DP, Carroll JS, Polyak K, Oesterreich S, Lee AV. Li Z, et al. Among authors: gertz j. bioRxiv [Preprint]. 2024 Jul 2:2024.06.28.601163. doi: 10.1101/2024.06.28.601163. bioRxiv. 2024. PMID: 39005294 Free PMC article. Preprint.
107 results