Zhang WC - Search Results

1

Discovery of a nitroaromatic nannocystin with potent in vivo anticancer activity against colorectal cancer by targeting AKT1.

Zhang H, Xie F, Yuan XY, Dai XT, Tian YF, Sun MM, Yu SQ, Cai JY, Sun B, Zhang WC, Shan CL. Zhang H, et al. Among authors: zhang wc. Acta Pharmacol Sin. 2024 May;45(5):1044-1059. doi: 10.1038/s41401-024-01231-w. Epub 2024 Feb 7. Acta Pharmacol Sin. 2024. PMID: 38326625

2

Total Synthesis of Nannocystin A.

Yang Z, Xu X, Yang CH, Tian Y, Chen X, Lian L, Pan W, Su X, Zhang W, Chen Y. Yang Z, et al. Org Lett. 2016 Nov 4;18(21):5768-5770. doi: 10.1021/acs.orglett.6b02729. Epub 2016 Oct 13. Org Lett. 2016. PMID: 27736074

3

Synthesis and biological evaluation of nannocystin analogues toward understanding the binding role of the (2R,3S)-Epoxide in nannocystin A.

Tian Y, Xu X, Ding Y, Hao X, Bai Y, Tang Y, Zhang X, Li Q, Yang Z, Zhang W, Chen Y. Tian Y, et al. Eur J Med Chem. 2018 Apr 25;150:626-632. doi: 10.1016/j.ejmech.2018.03.012. Epub 2018 Mar 20. Eur J Med Chem. 2018. PMID: 29554614

4

Site-directed late-stage diversification of macrocyclic nannocystins facilitating anticancer SAR and mode of action studies.

Zhang H, Tian Y, Yuan X, Xie F, Yu S, Cai J, Sun B, Shan C, Zhang W. Zhang H, et al. RSC Med Chem. 2022 Dec 22;14(2):299-312. doi: 10.1039/d2md00393g. eCollection 2023 Feb 22. RSC Med Chem. 2022. PMID: 36846368 Free PMC article.

5

Anticancer Small-Molecule Agents Targeting Eukaryotic Elongation Factor 1A: State of the Art.

Zhang H, Cai J, Yu S, Sun B, Zhang W. Zhang H, et al. Int J Mol Sci. 2023 Mar 8;24(6):5184. doi: 10.3390/ijms24065184. Int J Mol Sci. 2023. PMID: 36982256 Free PMC article. Review.

6

Heck Macrocyclization in Forging Non-Natural Large Rings including Macrocyclic Drugs.

Cai J, Sun B, Yu S, Zhang H, Zhang W. Cai J, et al. Int J Mol Sci. 2023 May 4;24(9):8252. doi: 10.3390/ijms24098252. Int J Mol Sci. 2023. PMID: 37175956 Free PMC article. Review.

7

The eEF1A protein in cancer: Clinical significance, oncogenic mechanisms, and targeted therapeutic strategies.

Zhang W, Wang J, Shan C. Zhang W, et al. Pharmacol Res. 2024 Jun;204:107195. doi: 10.1016/j.phrs.2024.107195. Epub 2024 Apr 25. Pharmacol Res. 2024. PMID: 38677532 Free article. Review.

8

From Target-Oriented to Motif-Oriented: A Case Study on Nannocystin Total Synthesis.

Zhang W. Zhang W. Molecules. 2020 Nov 15;25(22):5327. doi: 10.3390/molecules25225327. Molecules. 2020. PMID: 33203102 Free PMC article. Review.

9

Heck macrocyclization in natural product total synthesis.

Zhang W. Zhang W. Nat Prod Rep. 2021 Jun 23;38(6):1109-1135. doi: 10.1039/d0np00087f. Nat Prod Rep. 2021. PMID: 33662070 Review.

10

Cyclic Depsipeptide BE-43547A₂ : Synthesis and Activity against Pancreatic Cancer Stem Cells.

Sun Y, Ding Y, Li D, Zhou R, Su X, Yang J, Guo X, Chong C, Wang J, Zhang W, Bai C, Wang L, Chen Y. Sun Y, et al. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14627-14631. doi: 10.1002/anie.201709744. Epub 2017 Oct 24. Angew Chem Int Ed Engl. 2017. PMID: 28984401

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