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Page 1
A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer.
Foote JB, Mattox TE, Keeton AB, Chen X, Smith F, Berry KL, Holmes T, Wang J, Huang CH, Ward AB, Mitra AK, Ramirez-Alcantara V, Hardy C, Fleten KG, Flatmark K, Yoon KJ, Sarvesh S, Nagaraju GP, Bandi DSR, Maxuitenko YY, Valiyaveettil J, Carstens JL, Buchsbaum DJ, Yang J, Zhou G, Nurmemmedov E, Babic I, Gaponenko V, Abdelkarim H, Boyd MR, Gorman GS, Manne U, Bae S, El-Rayes BF, Piazza GA. Foote JB, et al. bioRxiv [Preprint]. 2024 Oct 7:2023.05.17.541233. doi: 10.1101/2023.05.17.541233. bioRxiv. 2024. Update in: Cancer Res. 2024 Dec 19. doi: 10.1158/0008-5472.CAN-24-0323 PMID: 38328254 Free PMC article. Updated. Preprint.
Pan-RAS inhibitors: Hitting multiple RAS isozymes with one stone.
Coley AB, Ward A, Keeton AB, Chen X, Maxuitenko Y, Prakash A, Li F, Foote JB, Buchsbaum DJ, Piazza GA. Coley AB, et al. Among authors: foote jb. Adv Cancer Res. 2022;153:131-168. doi: 10.1016/bs.acr.2021.07.009. Epub 2021 Aug 26. Adv Cancer Res. 2022. PMID: 35101229 Review.
A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer.
Foote JB, Mattox TE, Keeton AB, Chen X, Smith FT, Berry K, Holmes TW, Wang J, Huang CH, Ward A, Mitra AK, Ramirez-Alcantara V, Hardy C, Fleten KG, Flatmark K, Yoon KJ, Sarvesh S, Nagaraju GP, Bandi DSR, Maxuitenko YY, Valiyaveettil J, Carstens JL, Buchsbaum DJ, Yang J, Zhou G, Nurmemmedov E, Babic I, Gaponeko V, Abdelkarim H, Boyd MR, Gorman G, Manne U, Bae S, El-Rayes BF, Piazza GA. Foote JB, et al. Cancer Res. 2024 Dec 19. doi: 10.1158/0008-5472.CAN-24-0323. Online ahead of print. Cancer Res. 2024. PMID: 39700396
A mouse model of ZTTK syndrome reveals indispensable SON functions in organ development and hematopoiesis.
Vukadin L, Park B, Mohamed M, Li H, Elkholy A, Torrelli-Diljohn A, Kim JH, Jeong K, Murphy JM, Harvey CA, Dunlap S, Gehrs L, Lee H, Kim HG, Lee SN, Stanford D, Barrington RA, Foote JB, Sorace AG, Welner RS, Hildreth BE 3rd, Lim SS, Ahn EE. Vukadin L, et al. Among authors: foote jb. bioRxiv [Preprint]. 2023 Nov 19:2023.11.19.567732. doi: 10.1101/2023.11.19.567732. bioRxiv. 2023. Update in: JCI Insight. 2024 Mar 8;9(5):e175053. doi: 10.1172/jci.insight.175053 PMID: 38014320 Free PMC article. Updated. Preprint.
Pulmonary Fibrosis Ferret Model Demonstrates Sustained Fibrosis, Restrictive Physiology, and Aberrant Repair.
Peabody Lever JE, Li Q, Pavelkova N, Hussain SS, Bakshi S, Ren JQ, Jones LI, Kennemur J, Weupe M, Campos-Gomez J, Tang L, Lever JMP, Wang D, Stanford DD, Foote J, Harrod KS, Kim H, Phillips SE, Rowe SM. Peabody Lever JE, et al. bioRxiv [Preprint]. 2024 Jun 6:2024.06.04.597198. doi: 10.1101/2024.06.04.597198. bioRxiv. 2024. PMID: 38895273 Free PMC article. Preprint.
Mucociliary Transport Deficiency and Disease Progression in Syrian Hamsters with SARS-CoV-2 Infection.
Li Q, Vijaykumar K, Philips SE, Hussain SS, Huynh VN, Fernandez-Petty CM, Lever JEP, Foote JB, Ren J, Campos-Gómez J, Daya FA, Hubbs NW, Kim H, Onuoha E, Boitet ER, Fu L, Leung HM, Yu L, Detchemendy TW, Schaefers LT, Tipper JL, Edwards LJ, Leal SM Jr, Harrod KS, Tearney GJ, Rowe SM. Li Q, et al. Among authors: foote jb. bioRxiv [Preprint]. 2022 Jan 18:2022.01.16.476016. doi: 10.1101/2022.01.16.476016. bioRxiv. 2022. Update in: JCI Insight. 2023 Jan 10;8(1):e163962. doi: 10.1172/jci.insight.163962 PMID: 35075457 Free PMC article. Updated. Preprint.
Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine.
Nagaraju GP, Saddala MS, Foote JB, Khaliq AM, Masood A, Golivi Y, Bandi DSR, Sarvesh S, Reddy SP, Switchenko J, Carstens JL, Akce M, Herting C, Alese OB, Yoon KJ, Manne U, Bhasin MK, Lesinski GB, Sukhatme VP, El-Rayes BF. Nagaraju GP, et al. Among authors: foote jb. Cell Rep Med. 2024 Dec 17:101881. doi: 10.1016/j.xcrm.2024.101881. Online ahead of print. Cell Rep Med. 2024. PMID: 39730001 Free article.
ADT-1004: A First-in-Class, Orally Bioavailable Selective pan-RAS Inhibitor for Pancreatic Ductal Adenocarcinoma.
Reddy Bandi DS, Nagaraju GP, Sarvesh S, Carstens JL, Foote JB, Graff EC, Fang YD, Keeton AB, Chen X, Berry KL, Bae S, Akce M, Gorman G, Yoon KJ, Manne U, Boyd MR, Buchsbaum DJ, Azmi AS, Maxuitenko YY, Piazza GA, El-Rayes BF. Reddy Bandi DS, et al. Among authors: foote jb. bioRxiv [Preprint]. 2024 Oct 8:2024.10.04.616725. doi: 10.1101/2024.10.04.616725. bioRxiv. 2024. PMID: 39416034 Free PMC article. Preprint.
58 results