Verhaegen Y - Search Results

1

Identification of novel human CC chemokine receptor 8 (CCR8) antagonists via the synthesis of naphthalene amide and sulfonamide isosteres.

Verhaegen Y, Liu L, Nguyen TT, Loy TV, Schols D, Voet ARD, Dehaen W, De Jonghe S. Verhaegen Y, et al. Bioorg Chem. 2024 Apr;145:107181. doi: 10.1016/j.bioorg.2024.107181. Epub 2024 Feb 8. Bioorg Chem. 2024. PMID: 38354503

2

Palladium-catalyzed cross-coupling reactions on a bromo-naphthalene scaffold in the search for novel human CC chemokine receptor 8 (CCR8) antagonists.

Verhaegen Y, Liu L, Nguyen TT, Van Loy T, Voet ARD, Schols D, Dehaen W, De Jonghe S. Verhaegen Y, et al. Bioorg Chem. 2021 Feb;107:104560. doi: 10.1016/j.bioorg.2020.104560. Epub 2020 Dec 16. Bioorg Chem. 2021. PMID: 33383325

3

Synthesis and structure-activity relationship study of phenoxybenzylpiperazine analogues as CCR8 agonists.

Li Q, Claes S, Verhaegen Y, Anthonissen S, Van Loy T, Schols D, Dehaen W, De Jonghe S. Li Q, et al. Among authors: verhaegen y. Bioorg Chem. 2023 Oct;139:106755. doi: 10.1016/j.bioorg.2023.106755. Epub 2023 Jul 28. Bioorg Chem. 2023. PMID: 37544272

4

Biological characterization of ligands targeting the human CC chemokine receptor 8 (CCR8) reveals the biased signaling properties of small molecule agonists.

Liu L, Doijen J, D'huys T, Verhaegen Y, Dehaen W, De Jonghe S, Schols D, Van Loy T. Liu L, et al. Among authors: verhaegen y. Biochem Pharmacol. 2021 Jun;188:114565. doi: 10.1016/j.bcp.2021.114565. Epub 2021 Apr 17. Biochem Pharmacol. 2021. PMID: 33872569 Free article.

5

Assembly of fully substituted triazolochromenes via a novel multicomponent reaction or mechanochemical synthesis.

Vroemans R, Verhaegen Y, Dieu MTT, Dehaen W. Vroemans R, et al. Among authors: verhaegen y. Beilstein J Org Chem. 2018 Oct 22;14:2689-2697. doi: 10.3762/bjoc.14.246. eCollection 2018. Beilstein J Org Chem. 2018. PMID: 30410630 Free PMC article.

6

Implementation of the CREED approach for environmental assessments.

Di Paolo C, Bramke I, Stauber J, Whalley C, Otter R, Verhaegen Y, Nowell LH, Ryan AC. Di Paolo C, et al. Among authors: verhaegen y. Integr Environ Assess Manag. 2024 Jul;20(4):1019-1034. doi: 10.1002/ieam.4909. Epub 2024 Mar 1. Integr Environ Assess Manag. 2024. PMID: 38426820

7

Petroleum refinery effluent contribution to chemical mixture toxic pressure in the environment.

Wang J, Smit MGD, Verhaegen Y, Nolte TM, Redman AD, Hendriks AJ, Hjort M. Wang J, et al. Among authors: verhaegen y. Chemosphere. 2023 Jan;311(Pt 2):137127. doi: 10.1016/j.chemosphere.2022.137127. Epub 2022 Nov 2. Chemosphere. 2023. PMID: 36334744 Free article.

8

Organotins in North Sea brown shrimp (Crangon crangon L.) after implementation of the TBT ban.

Verhaegen Y, Monteyne E, Neudecker T, Tulp I, Smagghe G, Cooreman K, Roose P, Parmentier K. Verhaegen Y, et al. Chemosphere. 2012 Mar;86(10):979-84. doi: 10.1016/j.chemosphere.2011.11.028. Epub 2011 Dec 10. Chemosphere. 2012. PMID: 22154339

9

The heterodimeric ecdysteroid receptor complex in the brown shrimp Crangon crangon: EcR and RXR isoform characteristics and sensitivity towards the marine pollutant tributyltin.

Verhaegen Y, Parmentier K, Swevers L, Renders E, Rougé P, De Coen W, Cooreman K, Smagghe G. Verhaegen Y, et al. Gen Comp Endocrinol. 2011 May 15;172(1):158-69. doi: 10.1016/j.ygcen.2011.02.019. Epub 2011 Feb 25. Gen Comp Endocrinol. 2011. PMID: 21354421

10

The brown shrimp (Crangon crangon L.) ecdysteroid receptor complex: cloning, structural modeling of the ligand-binding domain and functional expression in an EcR-deficient Drosophila cell line.

Verhaegen Y, Parmentier K, Swevers L, Rougé P, Soin T, De Coen W, Cooreman K, Smagghe G. Verhaegen Y, et al. Gen Comp Endocrinol. 2010 Sep 15;168(3):415-23. doi: 10.1016/j.ygcen.2010.05.007. Epub 2010 May 31. Gen Comp Endocrinol. 2010. PMID: 20515691

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