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Targeted inhibition of SCFSKP2 confers anti-tumor activities resulting in a survival benefit in osteosarcoma.
Wang J, Ferrena A, Zhang R, Singh S, Viscarret V, Al-Harden W, Aldahamsheh O, Borjihan H, Singla A, Yaguare S, Tingling J, Zi X, Lo Y, Gorlick R, Schwartz EL, Zhao H, Yang R, Geller DS, Zheng D, Hoang BH. Wang J, et al. Among authors: schwartz el. Oncogene. 2024 Mar;43(13):962-975. doi: 10.1038/s41388-024-02942-4. Epub 2024 Feb 14. Oncogene. 2024. PMID: 38355807 Free PMC article.
Skp2 depletion reduces tumor-initiating properties and promotes apoptosis in synovial sarcoma.
Wang J, Sato K, O'Donnell E, Singla A, Yaguare S, Aldahamsheh O, Batko B, Borjihan H, Tingling J, Zhang J, Weiser DA, Loeb DM, Gorlick R, Schwartz EL, Yang R, Zi X, Zhao H, Geller DS, Hoang BH. Wang J, et al. Among authors: schwartz el. Transl Oncol. 2020 Oct;13(10):100809. doi: 10.1016/j.tranon.2020.100809. Epub 2020 Jul 2. Transl Oncol. 2020. PMID: 32623326 Free PMC article.
The interaction of SKP2 with p27 enhances the progression and stemness of osteosarcoma.
Wang J, Aldahamsheh O, Ferrena A, Borjihan H, Singla A, Yaguare S, Singh S, Viscarret V, Tingling J, Zi X, Lo Y, Gorlick R, Zheng D, Schwartz EL, Zhao H, Yang R, Geller DS, Hoang BH. Wang J, et al. Among authors: schwartz el. Ann N Y Acad Sci. 2021 Apr;1490(1):90-104. doi: 10.1111/nyas.14578. Epub 2021 Feb 16. Ann N Y Acad Sci. 2021. PMID: 33594717 Free PMC article.
SKP2 Knockout in Rb1/p53-Deficient Mouse Models of Osteosarcoma Induces Immune Infiltration and Drives a Transcriptional Program with a Favorable Prognosis.
Ferrena A, Wang J, Zhang R, Karadal-Ferrena B, Al-Hardan W, Singh S, Borjihan H, Schwartz EL, Zhao H, Oktay MH, Yang R, Geller DS, Hoang BH, Zheng D. Ferrena A, et al. Among authors: schwartz el. Mol Cancer Ther. 2024 Feb 1;23(2):223-234. doi: 10.1158/1535-7163.MCT-23-0173. Mol Cancer Ther. 2024. PMID: 37871911 Free PMC article.
140 results