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474 results

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Molecular Pharmacology of Selective NaV1.6 and Dual NaV1.6/NaV1.2 Channel Inhibitors that Suppress Excitatory Neuronal Activity Ex Vivo.
Goodchild SJ, Shuart NG, Williams AD, Ye W, Parrish RR, Soriano M, Thouta S, Mezeyova J, Waldbrook M, Dean R, Focken T, Ghovanloo MR, Ruben PC, Scott F, Cohen CJ, Empfield J, Johnson JP. Goodchild SJ, et al. Among authors: soriano m. ACS Chem Neurosci. 2024 Mar 20;15(6):1169-1184. doi: 10.1021/acschemneuro.3c00757. Epub 2024 Feb 15. ACS Chem Neurosci. 2024. PMID: 38359277 Free PMC article.
Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective NaV1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy.
Focken T, Burford K, Grimwood ME, Zenova A, Andrez JC, Gong W, Wilson M, Taron M, Decker S, Lofstrand V, Chowdhury S, Shuart N, Lin S, Goodchild SJ, Young C, Soriano M, Tari PK, Waldbrook M, Nelkenbrecher K, Kwan R, Lindgren A, de Boer G, Lee S, Sojo L, DeVita RJ, Cohen CJ, Wesolowski SS, Johnson JP Jr, Dehnhardt CM, Empfield JR. Focken T, et al. Among authors: soriano m. J Med Chem. 2019 Nov 14;62(21):9618-9641. doi: 10.1021/acs.jmedchem.9b01032. Epub 2019 Oct 3. J Med Chem. 2019. PMID: 31525968
Neural networks with quantum states of light.
Labay-Mora A, García-Beni J, Giorgi GL, Soriano MC, Zambrini R. Labay-Mora A, et al. Among authors: soriano mc. Philos Trans A Math Phys Eng Sci. 2024 Dec 30;382(2287):20230346. doi: 10.1098/rsta.2023.0346. Epub 2024 Dec 24. Philos Trans A Math Phys Eng Sci. 2024. PMID: 39717979 Review.
Conservation of function without conservation of amino acid sequence in intrinsically disordered transcriptional activation domains.
LeBlanc C, Stefani J, Soriano M, Lam A, Zintel MA, Kotha SR, Chase E, Pimentel-Solorio G, Vunnum A, Flug K, Fultineer A, Hummel N, Staller MV. LeBlanc C, et al. Among authors: soriano m. bioRxiv [Preprint]. 2024 Dec 5:2024.12.03.626510. doi: 10.1101/2024.12.03.626510. bioRxiv. 2024. PMID: 39677729 Free PMC article. Preprint.
Correction: Vilazodone, a Novel SSRI Antidepressant with 5-HT1A Partial Agonist Properties: Diminished Potentiation of Chronic Oral Methylphenidate-Induced Dynorphin Expression in the Striatum in Adolescent Male Rats.
Hrabak M, Ahmed R, Soriano MG, Powell A, Thanos PK, Steiner H. Hrabak M, et al. Among authors: soriano mg. Mol Neurobiol. 2024 Nov 14. doi: 10.1007/s12035-024-04621-7. Online ahead of print. Mol Neurobiol. 2024. PMID: 39541073 No abstract available.
474 results