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C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line.
Zoch A, Konieczny G, Auchynnikava T, Stallmeyer B, Rotte N, Heep M, Berrens RV, Schito M, Kabayama Y, Schöpp T, Kliesch S, Houston B, Nagirnaja L, O'Bryan MK, Aston KI, Conrad DF, Rappsilber J, Allshire RC, Cook AG, Tüttelmann F, O'Carroll D. Zoch A, et al. Among authors: cook ag. Mol Cell. 2024 Mar 21;84(6):1021-1035.e11. doi: 10.1016/j.molcel.2024.01.014. Epub 2024 Feb 14. Mol Cell. 2024. PMID: 38359823 Free article.
SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation.
Zoch A, Auchynnikava T, Berrens RV, Kabayama Y, Schöpp T, Heep M, Vasiliauskaitė L, Pérez-Rico YA, Cook AG, Shkumatava A, Rappsilber J, Allshire RC, O'Carroll D. Zoch A, et al. Among authors: cook ag. Nature. 2020 Aug;584(7822):635-639. doi: 10.1038/s41586-020-2557-5. Epub 2020 Jul 16. Nature. 2020. PMID: 32674113 Free PMC article.
Two-factor authentication underpins the precision of the piRNA pathway.
Dias Mirandela M, Zoch A, Leismann J, Webb S, Berrens RV, Valsakumar D, Kabayama Y, Auchynnikava T, Schito M, Chowdhury T, MacLeod D, Xiang X, Zou J, Rappsilber J, Allshire RC, Voigt P, Cook AG, Barau J, O'Carroll D. Dias Mirandela M, et al. Among authors: cook ag. Nature. 2024 Oct;634(8035):979-985. doi: 10.1038/s41586-024-07963-3. Epub 2024 Sep 18. Nature. 2024. PMID: 39294378 Free PMC article.
SALL4 controls cell fate in response to DNA base composition.
Pantier R, Chhatbar K, Quante T, Skourti-Stathaki K, Cholewa-Waclaw J, Alston G, Alexander-Howden B, Lee HY, Cook AG, Spruijt CG, Vermeulen M, Selfridge J, Bird A. Pantier R, et al. Among authors: cook ag. Mol Cell. 2021 Feb 18;81(4):845-858.e8. doi: 10.1016/j.molcel.2020.11.046. Epub 2021 Jan 5. Mol Cell. 2021. PMID: 33406384 Free PMC article.
64 results