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Combinations of the azaquinazoline anti-Wolbachia agent, AWZ1066S, with benzimidazole anthelmintics synergise to mediate sub-seven-day sterilising and curative efficacies in experimental models of filariasis.
Hegde S, Marriott AE, Pionnier N, Steven A, Bulman C, Gunderson E, Vogel I, Koschel M, Ehrens A, Lustigman S, Voronin D, Tricoche N, Hoerauf A, Hübner MP, Sakanari J, Aljayyoussi G, Gusovsky F, Dagley J, Hong DW, O'Neill P, Ward SA, Taylor MJ, Turner JD. Hegde S, et al. Among authors: lustigman s. Front Microbiol. 2024 Feb 1;15:1346068. doi: 10.3389/fmicb.2024.1346068. eCollection 2024. Front Microbiol. 2024. PMID: 38362501 Free PMC article.
Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry.
Lin Y, Jung H, Bulman CA, Ng J, Vinck R, O'Beirne C, Moser MS, Tricoche N, Peguero R, Li RW, Urban JF, Pape PL, Pagniez F, Moretto M, Weil T, Lustigman S, Cariou K, Mitreva M, Sakanari JA, Gasser G. Lin Y, et al. Among authors: lustigman s. bioRxiv [Preprint]. 2023 Jun 30:2023.06.28.546819. doi: 10.1101/2023.06.28.546819. bioRxiv. 2023. Update in: J Med Chem. 2023 Dec 14;66(23):15867-15882. doi: 10.1021/acs.jmedchem.3c01333 PMID: 37425761 Free PMC article. Updated. Preprint.
Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry.
Lin Y, Jung H, Bulman CA, Ng J, Vinck R, O'Beirne C, Zhong S, Moser MS, Tricoche N, Peguero R, Li RW, Urban JF Jr, Le Pape P, Pagniez F, Moretto M, Weil T, Lustigman S, Cariou K, Mitreva M, Sakanari JA, Gasser G. Lin Y, et al. Among authors: lustigman s. J Med Chem. 2023 Dec 14;66(23):15867-15882. doi: 10.1021/acs.jmedchem.3c01333. Epub 2023 Nov 27. J Med Chem. 2023. PMID: 38009931
Optimized strategy for real-time qPCR detection of Onchocerca volvulus DNA in pooled Simulium sp. blackfly vectors.
Doherty M, Grant JR, Pilotte N, Bennuru S, Fischer K, Fischer PU, Lustigman S, Nutman TB, Pfarr K, Hoerauf A, Unnasch TR, Hassan HK, Wanji S, Lammie PJ, Ottesen E, Mackenzie C, Williams SA. Doherty M, et al. Among authors: lustigman s. PLoS Negl Trop Dis. 2023 Dec 14;17(12):e0011815. doi: 10.1371/journal.pntd.0011815. eCollection 2023 Dec. PLoS Negl Trop Dis. 2023. PMID: 38096317 Free PMC article.
Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to Onchocerca volvulus in Mice and Non-Human Primates.
Ryan NM, Hess JA, Robertson EJ, Tricoche N, Turner C, Davis J, Petrovsky N, Ferguson M, Rinaldi WJ, Wong VM, Shimada A, Zhan B, Bottazzi ME, Makepeace BL, Gray SA, Carter D, Lustigman S, Abraham D. Ryan NM, et al. Among authors: lustigman s. Vaccines (Basel). 2023 Jul 6;11(7):1212. doi: 10.3390/vaccines11071212. Vaccines (Basel). 2023. PMID: 37515028 Free PMC article.
180 results