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Page 1
A High Throughput Whole Blood Assay for Analysis of Multiple Antigen-Specific T Cell Responses in Human Mycobacterium tuberculosis Infection.
Whatney WE, Gandhi NR, Lindestam Arlehamn CS, Nizam A, Wu H, Quezada MJ, Campbell A, Allana S, Kabongo MM, Khayumbi J, Muchiri B, Ongalo J, Tonui J, Sasser LE, Fergus TJ, Ouma GS, Ouma SG, Beck AA, Mulligan MJ, Oladele A, Kaushal D, Cain KP, Waller L, Blumberg HM, Altman JD, Ernst JD, Rengarajan J, Day CL; TBRU-ASTRa Study Group. Whatney WE, et al. Among authors: sasser le. J Immunol. 2018 Apr 15;200(8):3008-3019. doi: 10.4049/jimmunol.1701737. Epub 2018 Mar 14. J Immunol. 2018. PMID: 29540577 Free PMC article.
Distinct Human NK Cell Phenotypes and Functional Responses to Mycobacterium tuberculosis in Adults From TB Endemic and Non-endemic Regions.
Harris LD, Khayumbi J, Ongalo J, Sasser LE, Tonui J, Campbell A, Odhiambo FH, Ouma SG, Alter G, Gandhi NR, Day CL. Harris LD, et al. Among authors: sasser le. Front Cell Infect Microbiol. 2020 Mar 24;10:120. doi: 10.3389/fcimb.2020.00120. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32266170 Free PMC article.
Activation-Induced Marker Expression Identifies Mycobacterium tuberculosis-Specific CD4 T Cells in a Cytokine-Independent Manner in HIV-Infected Individuals with Latent Tuberculosis.
Barham MS, Whatney WE, Khayumbi J, Ongalo J, Sasser LE, Campbell A, Franczek M, Kabongo MM, Ouma SG, Hayara FO, Gandhi NR, Day CL. Barham MS, et al. Among authors: sasser le. Immunohorizons. 2020 Oct 2;4(10):573-584. doi: 10.4049/immunohorizons.2000051. Immunohorizons. 2020. PMID: 33008839 Free PMC article.
Adults from Kisumu, Kenya have robust γδ T cell responses to Schistosoma mansoni, which are modulated by tuberculosis.
McLaughlin TA, Khayumbi J, Ongalo J, Matete D, Tonui J, Muchiri B, Sasser LE, Campbell A, Allana S, Ouma SG, Hayara FO, Gandhi NR, Day CL. McLaughlin TA, et al. Among authors: sasser le. PLoS Negl Trop Dis. 2020 Oct 12;14(10):e0008764. doi: 10.1371/journal.pntd.0008764. eCollection 2020 Oct. PLoS Negl Trop Dis. 2020. PMID: 33044959 Free PMC article.
The Impact of Diabetes and Prediabetes on Prevalence of Mycobacterium tuberculosis Infection Among Household Contacts of Active Tuberculosis Cases in Ethiopia.
Smith AGC, Kempker RR, Wassie L, Bobosha K, Nizam A, Gandhi NR, Auld SC, Magee MJ, Blumberg HM; Tuberculosis Research Unit: Role of Antigen Specific Responses in the Control of TB (TBRU-ASTRa) Study Group. Smith AGC, et al. Open Forum Infect Dis. 2022 Jun 30;9(7):ofac323. doi: 10.1093/ofid/ofac323. eCollection 2022 Jul. Open Forum Infect Dis. 2022. PMID: 36420425 Free PMC article.
Patterns and cofactors of polyfunctional mycobacteria-specific T cell response restoration following 6-month antiretroviral treatment in children living with HIV.
Day CL, Njuguna IN, Cranmer LM, Whatney WE, Pearson RA, Lindestam Arlehamn CS, Sette A, LaCourse SM, Escudero JN, Sasser LE, Mugo C, Okinyi HM, Maleche-Obimbo E, Wamalwa DC, John-Stewart GC. Day CL, et al. Among authors: sasser le. J Infect Dis. 2024 Dec 18:jiae630. doi: 10.1093/infdis/jiae630. Online ahead of print. J Infect Dis. 2024. PMID: 39693245
mRNA-encoded Cas13 can be used to treat dengue infections in mice.
Basu M, Zurla C, Auroni TT, Vanover D, Chaves LCS, Sadhwani H, Pathak H, Basu R, Beyersdorf JP, Amuda OO, Elsharkawy A, Mosur V, Arthur RA, Claussen H, Sasser LE, Wroe JA, Peck HE, Kumar M, Brinton MA, Santangelo PJ. Basu M, et al. Among authors: sasser le. Nat Microbiol. 2024 Aug;9(8):2160-2172. doi: 10.1038/s41564-024-01726-6. Epub 2024 Jun 5. Nat Microbiol. 2024. PMID: 38839984