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306 results

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Page 1
Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation.
Venkatasubramanian M, Schwartz L, Ramachandra N, Bennett J, Subramanian KR, Chen X, Gordon-Mitchell S, Fromowitz A, Pradhan K, Shechter D, Sahu S, Heiser D, Scherle P, Chetal K, Kulkarni A, Myers KC, Weirauch MT, Grimes HL, Starczynowski DT, Verma A, Salomonis N. Venkatasubramanian M, et al. Among authors: pradhan k. bioRxiv [Preprint]. 2024 Feb 8:2024.02.04.578798. doi: 10.1101/2024.02.04.578798. bioRxiv. 2024. PMID: 38370617 Free PMC article. Preprint.
Ribosomal protein control of hematopoietic stem cell transformation through direct, non-canonical regulation of metabolism.
Harris B, Singh DK, Verma M, Fahl SP, Rhodes M, Sprinkle SR, Wang M, Zhang Y, Perrigoue J, Kessel R, Peri S, West J, Giricz O, Boultwood J, Pellagatti A, Ramesh KH, Montagna C, Pradhan K, Tyner JW, Kennedy BK, Holinstat M, Steidl U, Sykes S, Verma A, Wiest DL. Harris B, et al. Among authors: pradhan k. bioRxiv [Preprint]. 2023 Jun 1:2023.05.31.543132. doi: 10.1101/2023.05.31.543132. bioRxiv. 2023. PMID: 37398007 Free PMC article. Preprint.
A STAT3 Degrader Demonstrates Pre-clinical Efficacy in Venetoclax resistant Acute Myeloid Leukemia.
Chakraborty S, Morganti C, Pena BR, Zhang H, Verma D, Zaldana K, Gitego N, Ma F, Aluri S, Pradhan K, Gordon S, Mantzaris I, Goldfinger M, Feldman E, Gritsman K, Shi Y, Hubner S, Qiu YH, Brown BD, Skwarska A, Verma A, Konopleva M, Tabe Y, Gavathiotis E, Colla S, Gollob J, Dey J, Kornblau SM, Koralov SB, Ito K, Shastri A. Chakraborty S, et al. Among authors: pradhan k. bioRxiv [Preprint]. 2024 Aug 7:2024.08.05.599788. doi: 10.1101/2024.08.05.599788. bioRxiv. 2024. PMID: 39211137 Free PMC article. Preprint.
Glutaminase inhibition in combination with azacytidine in myelodysplastic syndromes: Clinical efficacy and correlative analyses.
Konopleva M, DiNardo C, Bhagat T, Baran N, Lodi A, Saxena K, Cai T, Su X, Skwarska A, Guerra V, Kuruvilla V, Konoplev S, Gordon-Mitchell S, Pradhan K, Aluri S, Collins M, Sweeney S, Busquet J, Rathore A, Deng Q, Green M, Grant S, Demo S, Choudhary G, Sahu S, Agarwal B, Spodek M, Thiruthuvanathan V, Will B, Steidl U, Tippett G, Burger J, Borthakur G, Jabbour E, Pemmaraju N, Kadia T, Komblau S, Daver N, Naqvi K, Short N, Garcia-Manero G, Tiziani S, Verma A. Konopleva M, et al. Among authors: pradhan k. Res Sq [Preprint]. 2023 Feb 23:rs.3.rs-2518774. doi: 10.21203/rs.3.rs-2518774/v1. Res Sq. 2023. Update in: Nat Cancer. 2024 Oct;5(10):1515-1533. doi: 10.1038/s43018-024-00811-3. PMID: 36865338 Free PMC article. Updated. Preprint.
Immunotherapy-resistant acute lymphoblastic leukemia cells exhibit reduced CD19 and CD22 expression and BTK pathway dependency.
Aminov S, Giricz O, Melnekoff DT, Sica RA, Polishchuk V, Papazoglu C, Yates B, Wang HW, Sahu S, Wang Y, Gordon-Mitchell S, Leshchenko VV, Schinke C, Pradhan K, Aluri S, Sohn M, Barta SK, Agarwal B, Goldfinger M, Mantzaris I, Shastri A, Matsui W, Steidl U, Brody JD, Shah NN, Parekh S, Verma A. Aminov S, et al. Among authors: pradhan k. J Clin Invest. 2024 Feb 20;134(8):e175199. doi: 10.1172/JCI175199. J Clin Invest. 2024. PMID: 38376944 Free PMC article.
Socio-demographic determinants of myelofibrosis outcomes in an underserved center and the SEER national database.
Yan J, Hammami MB, Wei JX, Shah N, Goldfinger M, Mantzaris I, Kornblum N, Gritsman K, Sica A, Cooper D, Feldman E, Konopleva M, Pradhan K, Thakur R, Vegivinti C, Qasim A, Verma A, Goel S. Yan J, et al. Among authors: pradhan k. Ann Hematol. 2024 Sep;103(9):3543-3551. doi: 10.1007/s00277-024-05894-7. Epub 2024 Jul 24. Ann Hematol. 2024. PMID: 39046510 Free PMC article.
306 results