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Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation.
Venkatasubramanian M, Schwartz L, Ramachandra N, Bennett J, Subramanian KR, Chen X, Gordon-Mitchell S, Fromowitz A, Pradhan K, Shechter D, Sahu S, Heiser D, Scherle P, Chetal K, Kulkarni A, Myers KC, Weirauch MT, Grimes HL, Starczynowski DT, Verma A, Salomonis N. Venkatasubramanian M, et al. Among authors: weirauch mt. bioRxiv [Preprint]. 2024 Feb 8:2024.02.04.578798. doi: 10.1101/2024.02.04.578798. bioRxiv. 2024. PMID: 38370617 Free PMC article. Preprint.
Reconstructing the sequence specificities of RNA-binding proteins across eukaryotes.
Sasse A, Ray D, Laverty KU, Tam CL, Albu M, Zheng H, Lyudovyk O, Dalal T, Nie K, Magis C, Notredame C, Weirauch MT, Hughes TR, Morris Q. Sasse A, et al. Among authors: weirauch mt. bioRxiv [Preprint]. 2024 Oct 18:2024.10.15.618476. doi: 10.1101/2024.10.15.618476. bioRxiv. 2024. PMID: 39464061 Free PMC article. Preprint.
Role of Forkhead box F1 in the Pathobiology of Pulmonary Arterial Hypertension.
Gomez-Arroyo J, Houweling AC, Bogaard HJ, Aman J, Kitzmiller JA, Porollo A, Dooijes D, Meijboom LJ, Hale P, Pauciulo MW, Hong J, Zhu N, Welch C, Shen Y, Zacharias WJ, McCormack FX, Aldred MA, Weirauch MT, Graf S, Rhodes C, Chung WK, Whitsett JA, Martin LJ, Kalinichenko VV, Nichols WC. Gomez-Arroyo J, et al. Among authors: weirauch mt. bioRxiv [Preprint]. 2024 Sep 22:2024.09.18.611448. doi: 10.1101/2024.09.18.611448. bioRxiv. 2024. PMID: 39345371 Free PMC article. Preprint.
Inter-cellular mRNA Transfer Alters Human Pluripotent Stem Cell State.
Yoneyama Y, Zhang RR, Kimura M, Cai Y, Adam M, Parameswaran S, Masaki H, Mizuno N, Bhadury J, Maezawa S, Ochiai H, Nakauchi H, Potter SS, Weirauch MT, Takebe T. Yoneyama Y, et al. Among authors: weirauch mt. bioRxiv [Preprint]. 2024 Jun 27:2024.06.27.600209. doi: 10.1101/2024.06.27.600209. bioRxiv. 2024. PMID: 38979277 Free PMC article. Preprint.
Human cytomegalovirus infection coopts chromatin organization to diminish TEAD1 transcription factor activity.
Sayeed K, Parameswaran S, Beucler MJ, Edsall LE, VonHandorf A, Crowther A, Donmez O, Hass M, Richards S, Forney C, Wright J, Leong MML, Murray-Nerger LA, Gewurz BE, Kaufman KM, Harley JB, Zhao B, Miller WE, Kottyan LC, Weirauch MT. Sayeed K, et al. Among authors: weirauch mt. bioRxiv [Preprint]. 2024 May 22:2024.04.12.588762. doi: 10.1101/2024.04.12.588762. bioRxiv. 2024. PMID: 38645179 Free PMC article. Preprint.
Macrophage memories of early-life injury drive neonatal nociceptive priming.
Dourson AJ, Fadaka AO, Warshak AM, Paranjpe A, Weinhaus B, Queme LF, Hofmann MC, Evans HM, Donmez OA, Forney C, Weirauch MT, Kottyan LC, Lucas D, Deepe GS Jr, Jankowski MP. Dourson AJ, et al. Among authors: weirauch mt. Cell Rep. 2024 May 28;43(5):114129. doi: 10.1016/j.celrep.2024.114129. Epub 2024 Apr 18. Cell Rep. 2024. PMID: 38640063 Free PMC article.
Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort.
Virolainen SJ, Satish L, Biagini JM, Chaib H, Chang WC, Dexheimer PJ, Dixon MR, Dunn K, Fletcher D, Forney C, Granitto M, Hestand MS, Hurd M, Kauffman K, Lawson L, Martin LJ, Peña LD, Phelan KJ, Shook M, Weirauch MT, Khurana Hershey GK, Kottyan LC. Virolainen SJ, et al. Among authors: weirauch mt. JCI Insight. 2024 Apr 2;9(9):e178258. doi: 10.1172/jci.insight.178258. JCI Insight. 2024. PMID: 38564302 Free PMC article.
180 results