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Page 1
Inhibition of ULK1/2 and KRAS G12C controls tumor growth in preclinical models of lung cancer.
Ghazi PC, O'Toole KT, Srinivas Boggaram S, Scherzer MT, Silvis MR, Zhang Y, Bogdan M, Smith BD, Lozano G, Flynn DL, Snyder EL, Kinsey CG, McMahon M. Ghazi PC, et al. Among authors: silvis mr. bioRxiv [Preprint]. 2024 Jun 17:2024.02.06.579200. doi: 10.1101/2024.02.06.579200. bioRxiv. 2024. Update in: Elife. 2024 Aug 30;13:RP96992. doi: 10.7554/eLife.96992 PMID: 38370808 Free PMC article. Updated. Preprint.
Scalable approaches for generating, validating and incorporating data from high-throughput functional assays to improve clinical variant classification.
Padigepati SR, Stafford DA, Tan CA, Silvis MR, Jamieson K, Keyser A, Nunez PAC, Nicoludis JM, Manders T, Fresard L, Kobayashi Y, Araya CL, Aradhya S, Johnson B, Nykamp K, Reuter JA. Padigepati SR, et al. Among authors: silvis mr. Hum Genet. 2024 Aug;143(8):995-1004. doi: 10.1007/s00439-024-02691-0. Epub 2024 Aug 1. Hum Genet. 2024. PMID: 39085601 Free PMC article.
Lipopolysaccharide integrity primes bacterial sensitivity to a cell wall-degrading intermicrobial toxin.
Trotta KL, Hayes BM, Schneider JP, Wang J, Todor H, Grimes PR, Zhao Z, Hatleberg WL, Silvis MR, Kim R, Koo BM, Basler M, Chou S. Trotta KL, et al. Among authors: silvis mr. bioRxiv [Preprint]. 2023 May 2:2023.01.20.524922. doi: 10.1101/2023.01.20.524922. bioRxiv. 2023. Update in: PLoS Pathog. 2023 Jun 26;19(6):e1011454. doi: 10.1371/journal.ppat.1011454 PMID: 36747731 Free PMC article. Updated. Preprint.
Ceragenins and Antimicrobial Peptides Kill Bacteria through Distinct Mechanisms.
Mitchell G, Silvis MR, Talkington KC, Budzik JM, Dodd CE, Paluba JM, Oki EA, Trotta KL, Licht DJ, Jimenez-Morales D, Chou S, Savage PB, Gross CA, Marletta MA, Cox JS. Mitchell G, et al. Among authors: silvis mr. mBio. 2022 Feb 22;13(1):e0272621. doi: 10.1128/mbio.02726-21. Epub 2022 Jan 25. mBio. 2022. PMID: 35073755 Free PMC article.
Bacterial CRISPR screens for gene function.
Todor H, Silvis MR, Osadnik H, Gross CA. Todor H, et al. Among authors: silvis mr. Curr Opin Microbiol. 2021 Feb;59:102-109. doi: 10.1016/j.mib.2020.11.005. Epub 2020 Dec 4. Curr Opin Microbiol. 2021. PMID: 33285498 Free PMC article. Review.
31 results