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Page 1
Patient-centric Comparability Assessment of Biopharmaceuticals.
Blümel M, Cordoba-Rodriguez R, Carroll JA, Beardsley RL, Maggio F, Wylie D, Tsang V, Ehrick R, Francq BG, Pohl T, Taktak S, Spasoff A, Morrison A, Albarghouthi M. Blümel M, et al. Among authors: pohl t. J Pharm Sci. 2024 Jun;113(6):1415-1425. doi: 10.1016/j.xphs.2024.02.010. Epub 2024 Feb 17. J Pharm Sci. 2024. PMID: 38373591 Review.
An Intra-Company Analysis of Inherent Particles in Biologicals Shapes the Protein Particle Mitigation Strategy Across Development Stages.
Morar-Mitrica S, Pohl T, Theisen D, Boll B, Bechtold-Peters K, Schipflinger R, Beyer B, Zierow S, Kammüller M, Pribil A, Schmelzer B, Boehm S, Goetti M, Serno T. Morar-Mitrica S, et al. Among authors: pohl t. J Pharm Sci. 2023 May;112(5):1476-1484. doi: 10.1016/j.xphs.2023.01.023. Epub 2023 Jan 31. J Pharm Sci. 2023. PMID: 36731778
AIntibody: an experimentally validated in silico antibody discovery design challenge.
Erasmus MF, Spector L, Ferrara F, DiNiro R, Pohl TJ, Perea-Schmittle K, Wang W, Tessier PM, Richardson C, Turner L, Kumar S, Bedinger D, Sormanni P, Fernández-Quintero ML, Ward AB, Loeffler JR, Swanson OM, Deane CM, Raybould MIJ, Evers A, Sellmann C, Bachas S, Ruffolo J, Nastri HG, Ramesh K, Sørensen J, Croasdale-Wood R, Hijano O, Leal-Lopes C, Shahsavarian M, Qiu Y, Marcatili P, Vernet E, Akbar R, Friedensohn S, Wagner R, Kurella VB, Malhotra S, Kumar S, Kidger P, Almagro JC, Furfine E, Stanton M, Graff CP, Villalba SD, Tomszak F, Teixeira AAR, Hopkins E, Dovner M, D'Angelo S, Bradbury ARM. Erasmus MF, et al. Among authors: pohl tj. Nat Biotechnol. 2024 Nov;42(11):1637-1642. doi: 10.1038/s41587-024-02469-9. Nat Biotechnol. 2024. PMID: 39496931 No abstract available.
A new type of submarine chimneys built of halite.
Siebert C, Ionescu D, Mallast U, Merchel S, Merkel B, Möller P, Pavetich S, Pohl T, Rödiger T, Yechieli Y. Siebert C, et al. Among authors: pohl t. Sci Total Environ. 2024 Dec 10;955:176752. doi: 10.1016/j.scitotenv.2024.176752. Epub 2024 Oct 15. Sci Total Environ. 2024. PMID: 39419230 Free article.
A next-generation Fab library platform directly yielding drug-like antibodies with high affinity, diversity, and developability.
Ferrara F, Fanni A, Teixeira AAR, Molina E, Leal-Lopes C, DeAguero A, D'Angelo S, Erasmus MF, Spector L, Rodriguez Carnero LA, Li J, Pohl TJ, Suslov N, Desrumeaux K, McMahon C, Kathuria S, Bradbury ARM. Ferrara F, et al. Among authors: pohl tj. MAbs. 2024 Jan-Dec;16(1):2394230. doi: 10.1080/19420862.2024.2394230. Epub 2024 Aug 27. MAbs. 2024. PMID: 39192463 Free PMC article.
Touch sensation requires the mechanically gated ion channel ELKIN1.
Chakrabarti S, Klich JD, Khallaf MA, Hulme AJ, Sánchez-Carranza O, Baran ZM, Rossi A, Huang AT, Pohl T, Fleischer R, Fürst C, Hammes A, Bégay V, Hörnberg H, Finol-Urdaneta RK, Poole K, Dottori M, Lewin GR. Chakrabarti S, et al. Among authors: pohl t. Science. 2024 Mar;383(6686):992-998. doi: 10.1126/science.adl0495. Epub 2024 Feb 29. Science. 2024. PMID: 38422143
Compliance and regulatory considerations for the implementation of the multi-attribute-method by mass spectrometry in a quality control laboratory.
Gervais A, Dirksen EHC, Pohl T, Bechtold-Peters K, Burkitt W, D'Alessio V, Greven S, Lennard A, Li X, Lössner C, Niu B, Reusch D, O'Riordan T, Shearer JW, Spencer D, Xu W, Yi L. Gervais A, et al. Among authors: pohl t. Eur J Pharm Biopharm. 2023 Oct;191:57-67. doi: 10.1016/j.ejpb.2023.08.008. Epub 2023 Aug 13. Eur J Pharm Biopharm. 2023. PMID: 37582411 Free article.
239 results