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Systemic administration of blood-derived exosomes induced by remote ischemic post-conditioning, by delivering a specific cluster of miRNAs, ameliorates ischemic damage and neurological function.
Cuomo O, Anzilotti S, Brancaccio P, Cepparulo P, Lombardi G, Viscardi V, Vinciguerra A, Annunziato L, Pignataro G. Cuomo O, et al. Among authors: cepparulo p. J Cereb Blood Flow Metab. 2024 Dec;44(12):1459-1471. doi: 10.1177/0271678X241270284. Epub 2024 Aug 11. J Cereb Blood Flow Metab. 2024. PMID: 39129187
Anti-miRNA103/107 encapsulated in transferrin-conjugated lipid nanoparticles crosses blood-brain barrier and reduces brain ischemic damage.
Cepparulo P, Cuomo O, Campani V, Vinciguerra A, Sisalli MJ, Nele V, Anzilotti S, Valsecchi V, Casamassa A, Brancaccio P, Scorziello A, De Rosa G, Annunziato L, Pignataro G. Cepparulo P, et al. Mol Ther Nucleic Acids. 2024 Feb 2;35(1):102131. doi: 10.1016/j.omtn.2024.102131. eCollection 2024 Mar 12. Mol Ther Nucleic Acids. 2024. PMID: 38379726 Free PMC article.
The Na+/Ca2+ Exchanger 3 Is Functionally Coupled With the NaV1.6 Voltage-Gated Channel and Promotes an Endoplasmic Reticulum Ca2+ Refilling in a Transgenic Model of Alzheimer's Disease.
Piccialli I, Ciccone R, Secondo A, Boscia F, Tedeschi V, de Rosa V, Cepparulo P, Annunziato L, Pannaccione A. Piccialli I, et al. Among authors: cepparulo p. Front Pharmacol. 2021 Dec 8;12:775271. doi: 10.3389/fphar.2021.775271. eCollection 2021. Front Pharmacol. 2021. PMID: 34955845 Free PMC article.
17 results