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Metabolic engineering for optimized CAR-T cell therapy.
McPhedran SJ, Carleton GA, Lum JJ. McPhedran SJ, et al. Among authors: lum jj. Nat Metab. 2024 Mar;6(3):396-408. doi: 10.1038/s42255-024-00976-2. Epub 2024 Feb 22. Nat Metab. 2024. PMID: 38388705 Review.
Ubiquitinating the way to T cell metabolism.
McPhedran S, Lum JJ. McPhedran S, et al. Among authors: lum jj. J Cell Biol. 2022 Jul 4;221(7):e202206006. doi: 10.1083/jcb.202206006. Epub 2022 Jun 13. J Cell Biol. 2022. PMID: 35695892 Free PMC article.
Assessing the Immune Regulatory Role of Metabolites In Vitro.
McPhedran S, Choe J, MacPherson S, Kowalchuk G, Chan V, Kilgour MK, Lum JJ. McPhedran S, et al. Among authors: lum jj. Methods Mol Biol. 2023;2614:109-120. doi: 10.1007/978-1-0716-2914-7_8. Methods Mol Biol. 2023. PMID: 36587122
Autophagy Regulation of Metabolism Is Required for CD8+ T Cell Anti-tumor Immunity.
DeVorkin L, Pavey N, Carleton G, Comber A, Ho C, Lim J, McNamara E, Huang H, Kim P, Zacharias LG, Mizushima N, Saitoh T, Akira S, Beckham W, Lorzadeh A, Moksa M, Cao Q, Murthy A, Hirst M, DeBerardinis RJ, Lum JJ. DeVorkin L, et al. Among authors: lum jj. Cell Rep. 2019 Apr 9;27(2):502-513.e5. doi: 10.1016/j.celrep.2019.03.037. Cell Rep. 2019. PMID: 30970253 Free article.
1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer.
Kilgour MK, MacPherson S, Zacharias LG, Ellis AE, Sheldon RD, Liu EY, Keyes S, Pauly B, Carleton G, Allard B, Smazynski J, Williams KS, Watson PH, Stagg J, Nelson BH, DeBerardinis RJ, Jones RG, Hamilton PT, Lum JJ. Kilgour MK, et al. Among authors: lum jj. Sci Adv. 2021 Jan 20;7(4):eabe1174. doi: 10.1126/sciadv.abe1174. Print 2021 Jan. Sci Adv. 2021. PMID: 33523930 Free PMC article.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R… See abstract for full author list ➔ Klionsky DJ, et al. Among authors: lum jj. Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8. Autophagy. 2021. PMID: 33634751 Free PMC article.
99 results