Chapple DE - Search Results

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Synthesis and Preclinical Evaluation of Two Novel ⁶⁸Ga-Labeled Bispecific PSMA/FAP-Targeted Tracers with 2-Nal-Containing PSMA-Targeted Pharmacophore and Pyridine-Based FAP-Targeted Pharmacophore.

Verena A, Merkens H, Chen CC, Chapple DE, Wang L, Bendre S, Wong AAWL, Bénard F, Lin KS. Verena A, et al. Among authors: chapple de. Molecules. 2024 Feb 9;29(4):800. doi: 10.3390/molecules29040800. Molecules. 2024. PMID: 38398552 Free PMC article.

Unnatural amino acid substitutions to improve in vivo stability and tumor uptake of ⁶⁸Ga-labeled GRPR-targeted TacBOMB2 derivatives for cancer imaging with positron emission tomography.

Wang L, Kuo HT, Zhang Z, Zhang C, Chen CC, Chapple D, Wilson R, Colpo N, François Bénard, Lin KS. Wang L, et al. EJNMMI Radiopharm Chem. 2024 Feb 2;9(1):8. doi: 10.1186/s41181-024-00241-7. EJNMMI Radiopharm Chem. 2024. PMID: 38305955 Free PMC article.

Synthesis and Evaluation of the First ⁶⁸Ga-Labeled C-Terminal Hydroxamate-Derived Gastrin-Releasing Peptide Receptor-Targeted Tracers for Cancer Imaging with Positron Emission Tomography.

Wang L, Kuo HT, Chen CC, Chapple D, Colpo N, Ng P, Lau WS, Jozi S, Bénard F, Lin KS. Wang L, et al. Molecules. 2024 Jun 28;29(13):3102. doi: 10.3390/molecules29133102. Molecules. 2024. PMID: 38999054 Free PMC article.

Synthesis and Evaluation of ⁶⁸Ga- and ¹⁷⁷Lu-Labeled [Pro¹⁴]bombesin(8-14) Derivatives for Detection and Radioligand Therapy of Gastrin-Releasing Peptide Receptor-Expressing Cancer.

Wang L, Kuo HT, Chapple DE, Chen CC, Kurkowska S, Colpo N, Uribe C, Bénard F, Lin KS. Wang L, et al. Among authors: chapple de. Mol Pharm. 2024 Dec 2;21(12):6385-6397. doi: 10.1021/acs.molpharmaceut.4c00952. Epub 2024 Oct 26. Mol Pharm. 2024. PMID: 39460729

Controlling Reactivity and Selectivity in the Mizoroki-Heck Reaction: High Throughput Evaluation of 1,5-Diaza-3,7-diphosphacyclooctane Ligands.

Isbrandt ES, Chapple DE, Tu NTP, Dimakos V, Beardall AMM, Boyle PD, Rowley CN, Blacquiere JM, Newman SG. Isbrandt ES, et al. Among authors: chapple de. J Am Chem Soc. 2024 Feb 28;146(8):5650-5660. doi: 10.1021/jacs.3c14612. Epub 2024 Feb 15. J Am Chem Soc. 2024. PMID: 38359357

"Lignophines": lignin-based tertiary phosphines with metal-scavenging ability.

Hajirahimkhan S , Chapple DE , Gholami G , Blacquiere JM , Xu CC , Ragogna PJ . Hajirahimkhan S , et al. Among authors: chapple de. Chem Commun (Camb). 2020 Sep 14;56(71):10357-10360. doi: 10.1039/d0cc03636f. Epub 2020 Aug 6. Chem Commun (Camb). 2020. PMID: 32760984

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