Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

7 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
The Discovery and Preclinical Profile of ALG-000184, a Prodrug of the Potent Hepatitis B Virus Capsid Assembly Modulator ALG-001075.
Vendeville S, Amblard F, Bassit L, Beigelman LN, Blatt LM, Chen X, Chou L, Kum DB, Chanda S, Deval J, Geng X, Gupta K, Jekle A, Hu H, Hu X, Kang H, Liu C, Liu J, McGowan DC, Misner DL, Raboisson P, Sanchez AA, Serebryany V, Stoycheva AD, Symons JA, Tan H, Vanrusselt H, Williams C, Welch M, Zhang L, Zhang Q, Zhang Y, Schinazi RF, Smith DB, Debing Y. Vendeville S, et al. Among authors: vanrusselt h. J Med Chem. 2024 Dec 12;67(23):21126-21142. doi: 10.1021/acs.jmedchem.4c01814. Epub 2024 Nov 22. J Med Chem. 2024. PMID: 39575679
CAM-A-dependent HBV core aggregation induces apoptosis through ANXA1.
Taverniti V, Meiss-Heydmann L, Gadenne C, Vanrusselt H, Kum DB, Giannone F, Pessaux P, Schuster C, Baumert TF, Debing Y, Verrier ER. Taverniti V, et al. Among authors: vanrusselt h. JHEP Rep. 2024 Jun 10;6(10):101134. doi: 10.1016/j.jhepr.2024.101134. eCollection 2024 Oct. JHEP Rep. 2024. PMID: 39386256 Free PMC article.
An in vivo duck hepatitis B virus model recapitulates key aspects of nucleic acid polymer treatment outcomes in chronic hepatitis B patients.
Debing Y, Vanrusselt H, Degrauwe L, Silva de Oliveira DA, Kariuki CK, Ebwanga EJ, Bashir S, Merckx W, Thatikonda SK, Rajwanshi V, Gohil V, Hong J, Kum DB, Acosta Sanchez A, Chanda S, Blatt LM, Jekle A, Symons JA, Smith DB, Raboisson P, Lin TI, Beigelman L, Paeshuyse J. Debing Y, et al. Among authors: vanrusselt h. Antiviral Res. 2024 Apr;224:105835. doi: 10.1016/j.antiviral.2024.105835. Epub 2024 Feb 23. Antiviral Res. 2024. PMID: 38401714
Class A capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation.
Kum DB, Vanrusselt H, Acosta Sanchez A, Taverniti V, Verrier ER, Baumert TF, Liu C, Deval J, Corthout N, Munck S, Beigelman L, Blatt LM, Symons JA, Raboisson P, Jekle A, Vendeville S, Debing Y. Kum DB, et al. Among authors: vanrusselt h. Hepatology. 2023 Oct 1;78(4):1252-1265. doi: 10.1097/HEP.0000000000000428. Epub 2023 Apr 28. Hepatology. 2023. PMID: 37102495
CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia.
Lodder C, Scheyltjens I, Stancu IC, Botella Lucena P, Gutiérrez de Ravé M, Vanherle S, Vanmierlo T, Cremers N, Vanrusselt H, Brône B, Hanseeuw B, Octave JN, Bottelbergs A, Movahedi K, Dewachter I. Lodder C, et al. Among authors: vanrusselt h. Acta Neuropathol Commun. 2021 Jun 8;9(1):108. doi: 10.1186/s40478-021-01204-8. Acta Neuropathol Commun. 2021. PMID: 34103079 Free PMC article.
Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo.
Stancu IC, Cremers N, Vanrusselt H, Couturier J, Vanoosthuyse A, Kessels S, Lodder C, Brône B, Huaux F, Octave JN, Terwel D, Dewachter I. Stancu IC, et al. Among authors: vanrusselt h. Acta Neuropathol. 2019 Apr;137(4):599-617. doi: 10.1007/s00401-018-01957-y. Epub 2019 Feb 5. Acta Neuropathol. 2019. PMID: 30721409 Free PMC article.