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671 results

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Page 1
Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity.
Yao S, Harder A, Darki F, Chang YW, Li A, Nikouei K, Volpe G, Lundström JN, Zeng J, Wray N, Lu Y, Sullivan PF, Leffler JH. Yao S, et al. Among authors: sullivan pf. medRxiv [Preprint]. 2024 Jan 20:2024.01.18.24301478. doi: 10.1101/2024.01.18.24301478. medRxiv. 2024. Update in: Nat Commun. 2025 Jan 4;16(1):395. doi: 10.1038/s41467-024-55611-1 PMID: 38410450 Free PMC article. Updated. Preprint.
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.
Bryois J, Skene NG, Hansen TF, Kogelman LJA, Watson HJ, Liu Z; Eating Disorders Working Group of the Psychiatric Genomics Consortium; International Headache Genetics Consortium; 23andMe Research Team; Brueggeman L, Breen G, Bulik CM, Arenas E, Hjerling-Leffler J, Sullivan PF. Bryois J, et al. Among authors: sullivan pf. Nat Genet. 2020 May;52(5):482-493. doi: 10.1038/s41588-020-0610-9. Epub 2020 Apr 27. Nat Genet. 2020. PMID: 32341526 Free PMC article.
Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders.
Byrne EM, Zhu Z, Qi T, Skene NG, Bryois J, Pardinas AF, Stahl E, Smoller JW, Rietschel M; Bipolar Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Owen MJ, Walters JTR, O'Donovan MC, McGrath JG, Hjerling-Leffler J, Sullivan PF, Goddard ME, Visscher PM, Yang J, Wray NR. Byrne EM, et al. Among authors: sullivan pf. Mol Psychiatry. 2021 Jun;26(6):2070-2081. doi: 10.1038/s41380-020-0705-9. Epub 2020 May 12. Mol Psychiatry. 2021. PMID: 32398722 Free PMC article.
Genetic heterogeneity and subtypes of major depression.
Nguyen TD, Harder A, Xiong Y, Kowalec K, Hägg S, Cai N, Kuja-Halkola R, Dalman C, Sullivan PF, Lu Y. Nguyen TD, et al. Among authors: sullivan pf. Mol Psychiatry. 2022 Mar;27(3):1667-1675. doi: 10.1038/s41380-021-01413-6. Epub 2022 Jan 8. Mol Psychiatry. 2022. PMID: 34997191 Free PMC article.
Leveraging base-pair mammalian constraint to understand genetic variation and human disease.
Sullivan PF, Meadows JRS, Gazal S, Phan BN, Li X, Genereux DP, Dong MX, Bianchi M, Andrews G, Sakthikumar S, Nordin J, Roy A, Christmas MJ, Marinescu VD, Wang C, Wallerman O, Xue J, Yao S, Sun Q, Szatkiewicz J, Wen J, Huckins LM, Lawler A, Keough KC, Zheng Z, Zeng J, Wray NR, Li Y, Johnson J, Chen J; Zoonomia Consortium§; Paten B, Reilly SK, Hughes GM, Weng Z, Pollard KS, Pfenning AR, Forsberg-Nilsson K, Karlsson EK, Lindblad-Toh K. Sullivan PF, et al. Science. 2023 Apr 28;380(6643):eabn2937. doi: 10.1126/science.abn2937. Epub 2023 Apr 28. Science. 2023. PMID: 37104612 Free PMC article.
Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease.
Bergstedt J, Pasman JA, Ma Z, Harder A, Yao S, Parker N, Treur JL, Smit DJA, Frei O, Shadrin AA, Meijsen JJ, Shen Q, Hägg S, Tornvall P, Buil A, Werge T, Hjerling-Leffler J, Als TD, Børglum AD, Lewis CM, McIntosh AM, Valdimarsdóttir UA, Andreassen OA, Sullivan PF, Lu Y, Fang F. Bergstedt J, et al. Among authors: sullivan pf. Nat Cardiovasc Res. 2024;3(6):754-769. doi: 10.1038/s44161-024-00488-y. Epub 2024 Jun 17. Nat Cardiovasc Res. 2024. PMID: 38898929 Free PMC article.
Polygenic Risk Scores and Twin Concordance for Schizophrenia and Bipolar Disorder.
Song J, Pasman JA, Johansson V, Kuja-Halkola R, Harder A, Karlsson R, Lu Y, Kowalec K, Pedersen NL, Cannon TD, Hultman CM, Sullivan PF. Song J, et al. Among authors: sullivan pf. JAMA Psychiatry. 2024 Dec 1;81(12):1246-1252. doi: 10.1001/jamapsychiatry.2024.2406. JAMA Psychiatry. 2024. PMID: 39196586
Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease.
Bergstedt J, Pasman JA, Ma Z, Harder A, Yao S, Parker N, Treur JL, Smit DJA, Frei O, Shadrin AA, Meijsen JJ, Shen Q, Hägg S, Tornvall P, Buil A, Werge T, Hjerling-Leffler J, Als TD, Børglum AD, Lewis CM, McIntosh AM, Valdimarsdóttir UA, Andreassen OA, Sullivan PF, Lu Y, Fang F. Bergstedt J, et al. Among authors: sullivan pf. Nat Cardiovasc Res. 2024 Jun;3(6):754-769. doi: 10.1038/s44161-024-00488-y. Epub 2024 Jun 17. Nat Cardiovasc Res. 2024. PMID: 39215135
671 results