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Novel Fragment Inhibitors of PYCR1 from Docking-Guided X-ray Crystallography.
J Chem Inf Model. 2024 Mar 11;64(5):1704-1718. doi: 10.1021/acs.jcim.3c01879. Epub 2024 Feb 27.
J Chem Inf Model. 2024.
PMID: 38411104
Expression and kinetic characterization of PYCR3.
Meeks KR, Tanner JJ.
Meeks KR, et al.
Arch Biochem Biophys. 2023 Jan 1;733:109468. doi: 10.1016/j.abb.2022.109468. Epub 2022 Nov 19.
Arch Biochem Biophys. 2023.
PMID: 36414121
Free PMC article.
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Functional Impact of a Cancer-Related Variant in Human Δ1-Pyrroline-5-Carboxylate Reductase 1.
Daudu OI, Meeks KR, Zhang L, Seravalli J, Tanner JJ, Becker DF.
Daudu OI, et al. Among authors: meeks kr.
ACS Omega. 2023 Jan 10;8(3):3509-3519. doi: 10.1021/acsomega.2c07788. eCollection 2023 Jan 24.
ACS Omega. 2023.
PMID: 36713721
Free PMC article.
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Screening a knowledge-based library of low molecular weight compounds against the proline biosynthetic enzyme 1-pyrroline-5-carboxylate 1 (PYCR1).
Meeks KR, Bogner AN, Tanner JJ.
Meeks KR, et al.
Protein Sci. 2024 Jul;33(7):e5072. doi: 10.1002/pro.5072.
Protein Sci. 2024.
PMID: 39133178
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