Tanner JJ - Search Results

1

Novel Fragment Inhibitors of PYCR1 from Docking-Guided X-ray Crystallography.

Meeks KR, Ji J, Protopopov MV, Tarkhanova OO, Moroz YS, Tanner JJ. Meeks KR, et al. Among authors: tanner jj. J Chem Inf Model. 2024 Mar 11;64(5):1704-1718. doi: 10.1021/acs.jcim.3c01879. Epub 2024 Feb 27. J Chem Inf Model. 2024. PMID: 38411104

2

Expression and kinetic characterization of PYCR3.

Meeks KR, Tanner JJ. Meeks KR, et al. Among authors: tanner jj. Arch Biochem Biophys. 2023 Jan 1;733:109468. doi: 10.1016/j.abb.2022.109468. Epub 2022 Nov 19. Arch Biochem Biophys. 2023. PMID: 36414121 Free PMC article.

3

Structure-based engineering of minimal proline dehydrogenase domains for inhibitor discovery.

Bogner AN, Ji J, Tanner JJ. Bogner AN, et al. Among authors: tanner jj. Protein Eng Des Sel. 2022 Feb 17;35:gzac016. doi: 10.1093/protein/gzac016. Protein Eng Des Sel. 2022. PMID: 36448708 Free PMC article.

4

Functional Impact of a Cancer-Related Variant in Human Δ¹-Pyrroline-5-Carboxylate Reductase 1.

Daudu OI, Meeks KR, Zhang L, Seravalli J, Tanner JJ, Becker DF. Daudu OI, et al. Among authors: tanner jj. ACS Omega. 2023 Jan 10;8(3):3509-3519. doi: 10.1021/acsomega.2c07788. eCollection 2023 Jan 24. ACS Omega. 2023. PMID: 36713721 Free PMC article.

5

Screening a knowledge-based library of low molecular weight compounds against the proline biosynthetic enzyme 1-pyrroline-5-carboxylate 1 (PYCR1).

Meeks KR, Bogner AN, Tanner JJ. Meeks KR, et al. Among authors: tanner jj. Protein Sci. 2024 Jul;33(7):e5072. doi: 10.1002/pro.5072. Protein Sci. 2024. PMID: 39133178

6

Noncovalent Inhibition and Covalent Inactivation of Proline Dehydrogenase by Analogs of N-Propargylglycine.

Tanner JJ, Ji J, Bogner AN, Scott GK, Patel SM, Seravalli J, Gates KS, Benz CC, Becker DF. Tanner JJ, et al. Biochemistry. 2024 Nov 5;63(21):2855-2867. doi: 10.1021/acs.biochem.4c00429. Epub 2024 Oct 22. Biochemistry. 2024. PMID: 39437336

7

Identification of the NAD(P)H binding site of eukaryotic UDP-galactopyranose mutase.

Dhatwalia R, Singh H, Solano LM, Oppenheimer M, Robinson RM, Ellerbrock JF, Sobrado P, Tanner JJ. Dhatwalia R, et al. Among authors: tanner jj. J Am Chem Soc. 2012 Oct 31;134(43):18132-8. doi: 10.1021/ja308188z. Epub 2012 Oct 19. J Am Chem Soc. 2012. PMID: 23036087 Free PMC article.

8

In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1.

Christensen EM, Bogner AN, Vandekeere A, Tam GS, Patel SM, Becker DF, Fendt SM, Tanner JJ. Christensen EM, et al. Among authors: tanner jj. J Biol Chem. 2020 Dec 25;295(52):18316-18327. doi: 10.1074/jbc.RA120.016106. Epub 2020 Oct 27. J Biol Chem. 2020. PMID: 33109600 Free PMC article.

9

Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles.

Campbell AC, Prater AR, Bogner AN, Quinn TP, Gates KS, Becker DF, Tanner JJ. Campbell AC, et al. Among authors: tanner jj. ACS Chem Biol. 2021 Nov 19;16(11):2268-2279. doi: 10.1021/acschembio.1c00427. Epub 2021 Sep 20. ACS Chem Biol. 2021. PMID: 34542291 Free PMC article.

10

Structures of the Escherichia coli PutA proline dehydrogenase domain in complex with competitive inhibitors.

Zhang M, White TA, Schuermann JP, Baban BA, Becker DF, Tanner JJ. Zhang M, et al. Among authors: tanner jj. Biochemistry. 2004 Oct 5;43(39):12539-48. doi: 10.1021/bi048737e. Biochemistry. 2004. PMID: 15449943 Free PMC article.

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