Flagg T - Search Results

1

Monocyte NLRP3 inflammasome and interleukin-1β activation modulated by alpha-1 antitrypsin therapy in deficient individuals.

Gogoi D, Yu H, Casey M, Baird R, Yusuf A, Forde L, O' Brien ME, West JR, Flagg T, McElvaney NG, Eden E, Mueller C, Brantly ML, Geraghty P, Reeves EP. Gogoi D, et al. Among authors: flagg t. Thorax. 2024 Aug 19;79(9):822-833. doi: 10.1136/thorax-2023-221071. Thorax. 2024. PMID: 38418195 Free PMC article.

2

Novel SERPINA1 Alleles Identified through a Large Alpha-1 Antitrypsin Deficiency Screening Program and Review of Known Variants.

Wiesemann GS, Oshins RA, Flagg TO, Brantly ML. Wiesemann GS, et al. Among authors: flagg to. Chronic Obstr Pulm Dis. 2023 Jan 25;10(1):7-21. doi: 10.15326/jcopdf.2022.0321. Chronic Obstr Pulm Dis. 2023. PMID: 36367950 Free PMC article.

3

The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.

Khodayari N, Wang RL, Oshins R, Lu Y, Millett M, Aranyos AM, Mostofizadeh S, Scindia Y, Flagg TO, Brantly M. Khodayari N, et al. Among authors: flagg to. Int J Mol Sci. 2021 Dec 9;22(24):13255. doi: 10.3390/ijms222413255. Int J Mol Sci. 2021. PMID: 34948056 Free PMC article.

4

Correlation of alpha-1 antitrypsin levels and exosome associated neutrophil elastase endothelial injury in subjects with SARS-CoV2 infection.

Lascano J, Oshins R, Eagan C, Wadood Z, Qiang X, Flagg T, Scindia Y, Mehrad B, Brantly M, Khodayari N. Lascano J, et al. Among authors: flagg t. PLoS One. 2022 Sep 9;17(9):e0274427. doi: 10.1371/journal.pone.0274427. eCollection 2022. PLoS One. 2022. PMID: 36084115 Free PMC article.

5

Lung microhaemorrhage drives oxidative/inflammatory damage in α₁-antitrypsin deficiency.

Saltini C, Mohammad N, Xin Y, Alvarado R, Ghio AJ, Moneypenny CG, Riva A, Fu D, Flagg T, Saltini GFA, Arisi I, Fredenburg KM, Zhang Y, Lascano JE, Brantly M. Saltini C, et al. Among authors: flagg t. ERJ Open Res. 2023 Jun 12;9(3):00662-2022. doi: 10.1183/23120541.00662-2022. eCollection 2023 May. ERJ Open Res. 2023. PMID: 37313399 Free PMC article.

6

Nicotine induces multi-site phosphorylation of Bad in association with suppression of apoptosis.

Jin Z, Gao F, Flagg T, Deng X. Jin Z, et al. Among authors: flagg t. J Biol Chem. 2004 May 28;279(22):23837-44. doi: 10.1074/jbc.M402566200. Epub 2004 Mar 22. J Biol Chem. 2004. PMID: 15037618 Free article.

7

Bcl2 impedes DNA mismatch repair by directly regulating the hMSH2-hMSH6 heterodimeric complex.

Hou Y, Gao F, Wang Q, Zhao J, Flagg T, Zhang Y, Deng X. Hou Y, et al. Among authors: flagg t. J Biol Chem. 2007 Mar 23;282(12):9279-87. doi: 10.1074/jbc.M608523200. Epub 2007 Jan 26. J Biol Chem. 2007. PMID: 17259174 Free article.

8

Bcl2 suppresses DNA repair by enhancing c-Myc transcriptional activity.

Jin Z, May WS, Gao F, Flagg T, Deng X. Jin Z, et al. Among authors: flagg t. J Biol Chem. 2006 May 19;281(20):14446-56. doi: 10.1074/jbc.M511914200. Epub 2006 Mar 22. J Biol Chem. 2006. PMID: 16554306 Free article.

9

Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation.

Jin Z, Gao F, Flagg T, Deng X. Jin Z, et al. Among authors: flagg t. J Biol Chem. 2004 Sep 17;279(38):40209-19. doi: 10.1074/jbc.M404056200. Epub 2004 Jun 21. J Biol Chem. 2004. PMID: 15210690 Free article.

10

RNA Interference With Zilebesiran for Mild to Moderate Hypertension: The KARDIA-1 Randomized Clinical Trial.

Bakris GL, Saxena M, Gupta A, Chalhoub F, Lee J, Stiglitz D, Makarova N, Goyal N, Guo W, Zappe D, Desai AS; KARDIA-1 Study Group. Bakris GL, et al. JAMA. 2024 Mar 5;331(9):740-749. doi: 10.1001/jama.2024.0728. JAMA. 2024. PMID: 38363577 Free PMC article.

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