Keyes W - Search Results

1

Enhanced branched-chain amino acid metabolism improves age-related reproduction in C. elegans.

Lesnik C, Kaletsky R, Ashraf JM, Sohrabi S, Cota V, Sengupta T, Keyes W, Luo S, Murphy CT. Lesnik C, et al. Among authors: keyes w. Nat Metab. 2024 Apr;6(4):724-740. doi: 10.1038/s42255-024-00996-y. Epub 2024 Feb 28. Nat Metab. 2024. PMID: 38418585

2

Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity.

Templeman NM, Luo S, Kaletsky R, Shi C, Ashraf J, Keyes W, Murphy CT. Templeman NM, et al. Among authors: keyes w. Curr Biol. 2018 Mar 5;28(5):753-760.e4. doi: 10.1016/j.cub.2018.01.052. Epub 2018 Feb 22. Curr Biol. 2018. PMID: 29478855 Free PMC article.

3

An integrative tissue-network approach to identify and test human disease genes.

Yao V, Kaletsky R, Keyes W, Mor DE, Wong AK, Sohrabi S, Murphy CT, Troyanskaya OG. Yao V, et al. Among authors: keyes w. Nat Biotechnol. 2018 Oct 22:10.1038/nbt.4246. doi: 10.1038/nbt.4246. Online ahead of print. Nat Biotechnol. 2018. PMID: 30346941 Free PMC article.

4

CREB Non-autonomously Controls Reproductive Aging through Hedgehog/Patched Signaling.

Templeman NM, Cota V, Keyes W, Kaletsky R, Murphy CT. Templeman NM, et al. Among authors: keyes w. Dev Cell. 2020 Jul 6;54(1):92-105.e5. doi: 10.1016/j.devcel.2020.05.023. Epub 2020 Jun 15. Dev Cell. 2020. PMID: 32544391 Free PMC article.

5

Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria.

Mor DE, Sohrabi S, Kaletsky R, Keyes W, Tartici A, Kalia V, Miller GW, Murphy CT. Mor DE, et al. Among authors: keyes w. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26438-26447. doi: 10.1073/pnas.2009838117. Epub 2020 Oct 6. Proc Natl Acad Sci U S A. 2020. PMID: 33024014 Free PMC article.

6

High-throughput behavioral screen in C. elegans reveals Parkinson's disease drug candidates.

Sohrabi S, Mor DE, Kaletsky R, Keyes W, Murphy CT. Sohrabi S, et al. Among authors: keyes w. Commun Biol. 2021 Feb 15;4(1):203. doi: 10.1038/s42003-021-01731-z. Commun Biol. 2021. PMID: 33589689 Free PMC article.

7

Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs.

Lakhina V, Arey RN, Kaletsky R, Kauffman A, Stein G, Keyes W, Xu D, Murphy CT. Lakhina V, et al. Among authors: keyes w. Neuron. 2015 Jan 21;85(2):330-45. doi: 10.1016/j.neuron.2014.12.029. Neuron. 2015. PMID: 25611510 Free PMC article.

8

An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology.

Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch'ng Q. Fernandes de Abreu DA, et al. Among authors: keyes wd. PLoS Genet. 2014 Mar 27;10(3):e1004225. doi: 10.1371/journal.pgen.1004225. eCollection 2014 Mar. PLoS Genet. 2014. PMID: 24675767 Free PMC article.

9

Enhanced Branched-Chain Amino Acid Metabolism Improves Age-Related Reproduction in C. elegans.

Lesnik C, Kaletsky R, Ashraf JM, Sohrabi S, Cota V, Sengupta T, Keyes W, Luo S, Murphy CT. Lesnik C, et al. Among authors: keyes w. bioRxiv [Preprint]. 2024 Feb 9:2023.02.09.527915. doi: 10.1101/2023.02.09.527915. bioRxiv. 2024. Update in: Nat Metab. 2024 Apr;6(4):724-740. doi: 10.1038/s42255-024-00996-y PMID: 38370685 Free PMC article. Updated. Preprint.

10

Senescence diversity in muscle aging.

Durik M, Keyes WM. Durik M, et al. Among authors: keyes wm. Nat Aging. 2022 Jul;2(7):570-572. doi: 10.1038/s43587-022-00255-3. Nat Aging. 2022. PMID: 37117776 No abstract available.

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